Results 191 to 200 of about 3,144,476 (264)

Endothelin-1 Mediates Oxaliplatin Resistance via Activation of YAP Signaling in Colorectal Cancer. [PDF]

Oncol Res
Yang R, Yuan D, Liang C, Zhu S, Huang J, Zhang Y, He W, Li Q, Zhang H.   +8 more
europepmc   +1 more source

State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge

MedComm, Volume 7, Issue 2, February 2026.
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding, Zai Luo, Liao Zhang, Shaopeng Zhang, Renchao Zhang, Zhengjun Qiu, Chen Huang   +6 more
wiley   +1 more source

Fusobacterium nucleatum enhances oxaliplatin resistance in colon cancer by increasing PVT1 expression. [PDF]

J Transl Med
Gao K, Zhang J, Liu C, Yang Y, Wang J, Zhang J, Ma H, Wang F, Zhao L, Wang G.   +9 more
europepmc   +1 more source

Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang, Ruo‐Lan Shi, You‐Xia Huang, Li‐Ni Liu, Jia‐Sheng Tao, Xian‐Hui Li, Xiao‐Da Li   +6 more
wiley   +1 more source

Calycosin Targets the CYP1B1‐AKT/SP1‐GPX4 Axis to Modulate Ferroptosis in Colorectal Carcinogenesis

Phytotherapy Research, Volume 40, Issue 2, Page 721-736, February 2026.
Mechanism of Calycosin in Regulating Ferroptosis in Colorectal Cancer via Binding to CYP1B1. ABSTRACT Calycosin, a natural flavonoid small‐molecule compound derived from traditional Chinese medicine, has demonstrated remarkable pharmacological activity in the field of cancer therapy.
Lihan Bie, Xin Lei, Di Wu, Yang Zhang, Chengshan He, Luyao Liu, Jiawei Zhou, Xin Zhou, Yingying Lu, Zheng Xu   +9 more
wiley   +1 more source

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer. [PDF]

Int J Mol Med
Lai C, Jia X, Chen Y, Chen K, Wang F, Zhang Q, Xiang X, Chen ZS, Xu L, Dai S.   +9 more
europepmc   +1 more source

MicroRNA Profiling of Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells [PDF]

Oncomedicine, 2017
Bustamin Kosmo, Kee Wah Lee, Muhammad Sufyan bin Masroni, Sharne Leong, Wei Ern Ong, Hong Lyn Wong, Yi Yun Chang, Evelyn SC Koay, Sai Mun Leong, Karen Tan   +9 more
openaire   +1 more source

RCC1 Domain‐Containing Protein 1 Promotes Colon Cancer Malignant Progression by Activating Autophagy‐Dependent WNT5A Secretion in Cancer‐Associated Fibroblasts

Journal of the Royal Society of New Zealand, Volume 56, Issue 1, February 2026.
RCCD1 is upregulated in colon cancer and cancer‐associated fibroblasts (CAFs). In CAFs, RCCD1 overexpression activates AMPK/mTOR/ULK1 signaling, enhancing autophagy. This stimulates autophagic secretion of WNT5A. WNT5A then activates the nonclassical Wnt/CaMKII/ERK pathway in tumor cells, promoting epithelial‐mesenchymal transition (EMT), proliferation,
Chao Liu, Sheng Xu, Yuanyuan Liu, Yuntian Tang   +3 more
wiley   +1 more source

Targeting the ARL4C/RAP1/PI3K-Akt-mTOR signaling loop promotes ARL4C ubiquitination and reverses oxaliplatin resistance in colorectal cancer. [PDF]

Theranostics
Wang Y, Chang Z, Sun Z, Wang L, Li J, Li G, Wang Y, Zhang J, Ai L, Zhang Z, Dong J, Liu M.   +11 more
europepmc   +1 more source

Cancer Stem Cell Gene Profile as Predictor of Relapse in High Risk Stage II and Stage III, Radically Resected Colon Cancer Patients [PDF]

, 2013
Bearzi Italo, Bianconi Maristella, Bittoni Alessandro, Cascinu Stefano, Cecchini Luca, Del Prete Michela, Faloppi Luca, Giampieri Riccardo, Guerrieri Mario, Lezoche Giovanni, Loretelli Cristian, Mandolesi Alessandra, Piva Francesco, Scartozzi Mario   +13 more
core   +1 more source