Results 231 to 240 of about 47,533 (300)

Exosomal Non‐Coding RNAs in Gastrointestinal Cancer Drug Resistance: A Systematic Review of Emerging Mechanisms and Clinical Implications

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Gastrointestinal (GI) tumours are one of the most prevalent cancers globally. Even with normal GI function, individuals may develop neoplasms, highlighting the need to better understand the underlying causes of tumorigenesis. The emergence of tumour drug resistance represents the main reason for the failure of drug treatment; thus, it is ...
Mohsen Sharif‐zak, Zahra Sadeghloo, Fateme Binayi, Stefania Nobili, Sara Ashtari, Amir Sadeghi, Nayeralsadat Fatemi   +6 more
wiley   +1 more source

Cigarette smoke extract promotes metastasis and oxaliplatin resistance in colon adenocarcinoma through GDF15/ERBB2/AKT pathway. [PDF]

Eur J Med Res
Jiang W, Wang Y, Wang WJ, Zhou BC, Hu XS, Xu AM.   +5 more
europepmc   +1 more source

RABL6A Promotes Oxaliplatin Resistance in Tumor Cells and Is a New Marker of Survival for Resected Pancreatic Ductal Adenocarcinoma Patients [PDF]

, 2013
Viviane P. Muniz, Ryan W. Askeland, Xuefeng Zhang, Stephen M. Reed, Van S. Tompkins, Jussara Hagen, Bradley D. McDowell, Anna M. Button, Bruce A. Smith, Jamie A. Weydert, James J. Mezhir, Dawn E. Quelle   +11 more
openalex   +1 more source

Inhibitory Activity of Conferone on FAK Activity and Glutamine Metabolism in Human Colorectal Cancer

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Colorectal cancer (CRC) is a major global cause of death, with metastases and chemotherapy resistance contributing to poor outcomes. To identify natural compounds with anticancer potential against CRC and elucidate their action mechanisms, the cytotoxicity of 37 natural compounds was evaluated against the HCT116, leading to the identification ...
Hien Thi My Ong, Eda Ates, Jaeyong Jung, Jeong Soo Sung, Jae‐Chul Pyun, Min‐Jung Kang   +5 more
wiley   +1 more source

An integrative analysis of transcriptome, methylome and single-cell RNA sequencing data identifies UBE2H as a marker of oxaliplatin resistance in colorectal cancer. [PDF]

Cancer Cell Int
Fang J, Zhu Q, Hong B, Li X, Wang H.
europepmc   +1 more source

Tubocapsenolide A Overcomes Oxaliplatin Resistance in Colorectal Cancer by Targeting the PLK1-CEP55-ESCRT Axis to Suppress Nuclear Budding and Mitochondrial-derived Vesicles Extrusion

Yueying Yang, Yang Liu, Lu Wang, Jing Liang, Li Zhang, Zhiruo Zhang, Rui Zhu, Wen Xu, Shaohua Xu, Dejuan Sun, Ke Xiang, Yali Wang, Zhimin Fan, Zheng Wang, Wenyi Wei, Hua Li, Lixia Chen   +16 more
openalex   +1 more source

Targeting the NAD+/SIRT1 axis: A metabolic strategy to overcome oxaliplatin resistance in colorectal cancer. [PDF]

World J Gastroenterol
Hussain MS, Jakhmola V, Goyal K, Rekha A, Sultana A, Ali H, Gupta G.   +6 more
europepmc   +1 more source

DIRAS1 Drives Oxaliplatin Resistance in Colorectal Cancer via PHB1-Mediated Mitochondrial Homeostasis. [PDF]

Biology (Basel)
Long M, Ouyang Q, Wen J, Zeng X, Xu Z, Zhong S, Huang C, Luo JL.   +7 more
europepmc   +1 more source

DEPP1: A prognostic biomarker linked to stroma‑rich and immunosuppressive microenvironment, promoting oxaliplatin resistance in gastric cancer. [PDF]

Oncol Rep
Qiu X, Pan T, Kuang T, Shen Y, Zheng Y, Geng H, Ni B, Xia X, Zhu C, Zhang Z, Cao H, Tu L.   +11 more
europepmc   +1 more source

Alectinib and SALL4-Targeted Fatty Acid Oxidation: A Strategy to Combat Oxaliplatin Resistance in Gastric Cancer. [PDF]

Turk J Gastroenterol
Xiao Y, Fang K, Liao J, Zhou H, Zhu W, Liu Z, Ouyang H, Liu K.   +7 more
europepmc   +1 more source