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Unconventional oxazole formation from isocyanides
Chemical Communications, 2009The coupling of an acyl chloride with an isocyanide affords 2,5-disubstituted oxazoles under mild basic conditions instead of 4,5-disubstituted derivatives when using Schöllkopf conditions (butyllithium); this reaction constitutes a remarkable example of a base-induced chemoselective process in isocyanide chemistry.
El Kaim, Laurent +3 more
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Synthesis of 2,4,5‐Trisubstituted Oxazoles.
ChemInform, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
Guo-lin Zhang +2 more
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2009
Oxazoles from the condensation of equimolar amounts of aldehyde cyanohydrins and aromatic aldehydes in dry ether in the presence of dry hydrochloric acid.
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Oxazoles from the condensation of equimolar amounts of aldehyde cyanohydrins and aromatic aldehydes in dry ether in the presence of dry hydrochloric acid.
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