Results 91 to 100 of about 9,081 (170)
Palladium-catalyzed formation of oxazolidinones from biscarbamates: a mechanistic study
Oxazolidinones can be synthesized starting from cyclic biscarbamates via a palladium-catalyzed reaction. To test the proposed mechanism of this reaction, first, bicyclonorcarene endoperoxides derived from cyano and carbomethoxy cycloheptatrienes were ...
Benan Kilbas, Metin Balci
doaj +1 more source
As antibiotic resistance escalates into a global health crisis, novel therapeutic approaches against infectious diseases are in urgent need. Pseudomonas aeruginosa, an adaptable opportunistic pathogen, poses substantial challenges in treating a range of ...
Yi Wu +6 more
doaj +1 more source
Enantioselective Oxidative Coupling of the Titanium Enolate of 3-Phenylacetyl-2-oxazolidinone
Enantioselective oxidative coupling of titanium and ytterbium enolates of 1 bound to chiral diol, e.g., TADDOL 6, and bisoxazoline ligands with ferrocenium cation as oxidant affords dimers 2 with moderate to good ...
Phu Q. Nguyen (3064260) +1 more
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Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
The oxazolidinone antibacterials target the 50S subunit of prokaryotic ribosomes. To gain insight into their mechanism of action, the crystal structure of the canonical oxazolidinone, linezolid, has been determined bound to the Haloarcula marismortui 50S
Deping Wang (1992346) +6 more
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Relative stability of the key enamine, oxazolidinone, and imine intermediates in some proline-catalyzed asymmetric reactions [PDF]
Many proline-catalyzed asymmetric addition reactions with ketones as substrates were assumed to involve a key intermediate, an enamine, produced by the condensation of proline and ketone.
Hu, Yi-Fan, 胡一帆, Lu, Xin, 吕鑫
core
Synthesis of Spiro-Oxazolidinone Derivatives from Diacetone-D-Glucose
A practical synthesis of sugar-based spiro-oxazolidinones is ...
Lugiņina, Jevgeņija +5 more
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Activity of LCB01-0371, a Novel Oxazolidinone, against Mycobacterium abscessus
Mycobacterium abscessus is a highly pathogenic drug-resistant rapidly growing mycobacterium. In this study, we evaluated the in vitro , intracellular, and in vivo activities of LCB01-0371, a ...
Guehye Kim +10 more
core +1 more source
Cytoxazone: A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces ...
Hideaki Kakeya (502730) +5 more
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A new Lewis acid-catalyzed atom transfer radical cyclization reaction of unsaturated α-bromo oxazolidinone imides is reported. In the presence of Lewis acids such as Mg(ClO4)2 and Yb(OTf)3, a series of trans cyclic products was obtained in high yield (up
Yang, D +4 more
core +1 more source
For the first time, anodic methoxylation of 2-oxazolidinone was investigated on boron doped diamond (BDD) in CH3OH\H2SO4 medium. Voltammetric studies reveal that the 2-oxazolidinone gets oxidised at a potential of 1.5 V vs.
Selvamani, V. +4 more
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