Results 81 to 90 of about 9,081 (170)
, 2022 The appearance of transferable oxazolidinone resistance genes poses a major challenge to public health and environmental safety. These genes not only lead pathogenic bacteria to become resistant to linezolid but also reduce sensitivity to florfenicol ...
Qin Wang (109812) +6 more
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An Efficient Approach to the Synthesis of Novel Oxazolidinones as Potential Antimicrobial Agents
Journal of Chemistry, 2013 Oxazolidinone, either mononuclear or condensed with other heterocyclics, has established its importance in medicinal chemistry. A variety of biological activities have been reported by oxazolidinone derivatives.
Kavita Devi +4 more
doaj +1 more source
, 2010 Comparison of the oxazolidinone and enamine pathways in enantioselective aldol reactions by using density functional and ab initio transition states reveals that the oxazolidinone route does not provide the correct stereochemical outcome (see picture ...
Sharma, Akhilesh K., Sunoj, Raghavan B.
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Current Problems of Infections Caused by MRSA and Ways to Address Them
Антибиотики и Химиотерапия, 2020 The increase in the growth rate of MRSA as an etiologic factor has been recorded worldwide in recent years. The main problem of antibiotic resistance in Staphylococcus aureus is its resistance to beta-lactam antibiotics.
S. K. Zyryanov +2 more
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, 2016 A series of asymmetric free-radical-mediated intermolecular conjugate additions using a fluorous oxazolidinone chiral auxiliary has been completed.
Mukund P. Sibi (1633159) +3 more
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3-[2-(2-Amino-1H-benzo[d]imidazol-1-yl)ethyl]-1,3-oxazolidin-2-one
IUCrData, 2016 In the title compound, C12H14N4O2, the benzimidazole ring is almost planar (r.m.s. deviation = 0.03 Å), with the fused ring system slightly folded at the shared atoms, with a dihedral angle of 3.4 (1)°.
Abdellatif Bouayyadi +5 more
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Drug Design, Development and TherapyYanfei Lu,1,2 Fang Cai1,2 1Center for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, People’s ...
Lu Y, Cai F
doaj
Scientia Pharmaceutica, 2018 Bacterial resistance towards the existing class of antibacterial drugs continues to increase, posing a significant threat to the clinical usefulness of these drugs.
Oludotun Adebayo Phillips +2 more
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Synthetic Pathway for Carbohydrate-Based Spiro-Oxazolidinone Derivatives
Carbohydrate-heterocycle conjugates with spirocyclic junction have raised a particular interest in the last two decades. We report here a scalable synthesis of two diastereoisomeric series of oxazolidinone-carbohydrate conjugates with spiro-junction and ...
Rolava, Evija +3 more
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Construction of N-aryl oxazolidinone group from (R)-Glycidyl tosylate
, 2010 Oxazolidin-2-one은 유기 합성이나 의약화학 분야에서 매우 다양하게 활용되고 있는 작용기(functional group)이다. 특히 최근에는 항생제에 내성을 가지는 그람 양성균(Gram-positive bacteria)에 대응할 수 있는 약물로서, 종전의 항생제들과는 다른 작용 기전을 가지고 있는 oxazolidinone계열 항생제에 관한 연구가 활발히 이루어지고 있다.
김초롬
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