Results 61 to 70 of about 6,197 (174)

Palladium-catalyzed formation of oxazolidinones from biscarbamates: a mechanistic study

Beilstein Journal of Organic Chemistry, 2011
Oxazolidinones can be synthesized starting from cyclic biscarbamates via a palladium-catalyzed reaction. To test the proposed mechanism of this reaction, first, bicyclonorcarene endoperoxides derived from cyano and carbomethoxy cycloheptatrienes were ...
Benan Kilbas, Metin Balci
doaj   +1 more source

(R,R/S,S)-9-Benzyl-3-methyl-7-phenyl-1,6-dioxa-3,9-diazaspiro[4.4]nonane-2,8-dione

IUCrData, 2019
The title compound, C19H18N2O4, a rare example of a spirocyclic orthoamide, was synthesized by a double cyclization of a N-Boc protected sarcosine derivative.
Craig M. Forsyth, Zohreh Nazarian
doaj   +1 more source

One-pot synthesis of oxazolidinones and five-membered cyclic carbonates from epoxides and chlorosulfonyl isocyanate: theoretical evidence for an asynchronous concerted pathway

Beilstein Journal of Organic Chemistry, 2020
The one-pot reaction of chlorosulfonyl isocyanate (CSI) with epoxides having phenyl, benzyl and fused cyclic alkyl groups in different solvents under mild reaction conditions without additives and catalysts was studied.
Esra Demir, Ozlem Sari, Yasin Çetinkaya, Ufuk Atmaca, Safiye Sağ Erdem, Murat Çelik   +5 more
doaj   +1 more source

Multifaceted quorum-sensing inhibiting activity of 3-(Benzo[d][1,3]dioxol-4-yl)oxazolidin-2-one mitigates Pseudomonas aeruginosa virulence

Virulence
As antibiotic resistance escalates into a global health crisis, novel therapeutic approaches against infectious diseases are in urgent need. Pseudomonas aeruginosa, an adaptable opportunistic pathogen, poses substantial challenges in treating a range of ...
Yi Wu, Fulong Wen, Shiyi Gou, Qiman Ran, Yiwen Chu, Wenbo Ma, Kelei Zhao   +6 more
doaj   +1 more source

In-peptide synthesis of di-oxazolidinone and dehydroamino acid–oxazolidinone motifs as β-turn inducers

Organic & Biomolecular Chemistry, 2013
Small and easy-to-do mimetics of β-turns are of great interest to interfere with protein-protein recognition events mediated by β-turn recognition motifs. We propose a straightforward procedure for constraining the conformation of tetrapeptides lacking a pre-formed scaffold.
DE MARCO, ROSSELLA, GRECO, ARIANNA, RUPIANI, SEBASTIANO, TOLOMELLI, ALESSANDRA, TOMASINI, CLAUDIA, PIERACCINI, SILVIA, GENTILUCCI, LUCA   +6 more
openaire   +3 more sources

Oxazolidinones

EMC - Maladies infectieuses, 2010
James C.M. Brust, Franklin D Lowy
  +4 more sources

Methodological Considerations in the Evaluation of Ciprofol’s Effect on Postoperative Delirium in Elderly Patients [Letter]

Drug Design, Development and Therapy
Yanfei Lu,1,2 Fang Cai1,2 1Center for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, People’s ...
Lu Y, Cai F
doaj  

In vitro Susceptibility of Nontuberculous Mycobacteria to Tedizolid

Infection and Drug Resistance, 2022
Huiyun Zhang,1 Wenya Hua,1 Siran Lin,1 Yu Zhang,1 Xinchang Chen,1 Shiyong Wang,1 Jiazhen Chen,1 Wenhong Zhang1– 3 1Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center
Zhang H, Hua W, Lin S, Zhang Y, Chen X, Wang S, Chen J, Zhang W   +7 more
doaj  

Structure-Antibacterial Activity Relationships of N-Substituted-(d-/l-Alaninyl) 1H-1,2,3-Triazolylmethyl Oxazolidinones

Scientia Pharmaceutica, 2018
Bacterial resistance towards the existing class of antibacterial drugs continues to increase, posing a significant threat to the clinical usefulness of these drugs.
Oludotun Adebayo Phillips, Edet Ekpenyong Udo, Roselyn Jennifer D’silva   +2 more
doaj   +1 more source

An Efficient Approach to the Synthesis of Novel Oxazolidinones as Potential Antimicrobial Agents

Journal of Chemistry, 2013
Oxazolidinone, either mononuclear or condensed with other heterocyclics, has established its importance in medicinal chemistry. A variety of biological activities have been reported by oxazolidinone derivatives.
Kavita Devi, Yumna Asmat, Sonika Jain, Swapnil Sharma, Jaya Dwivedi   +4 more
doaj   +1 more source