Results 41 to 50 of about 6,197 (174)

The Effectiveness of Linezolid and Teicoplanin for Managing Infections After Burn Injuries: A Retrospective Study

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Gram‐positive infections in burn patients present significant treatment challenges. This study compared the efficacy and safety of linezolid vs. teicoplanin for managing such infections in a clinical setting. Methods We conducted a retrospective study involving 77 burn patients with confirmed Gram‐positive infections at ...
Abolfazl Zendehdel, Maryam Roham, Sanam Soltani, Amirali Jahanshahi, Somayeh Heidarizadi   +4 more
wiley   +1 more source

Population Pharmacokinetic Model‐Based Optimization of Linezolid Dosing in Hematooncological Patients With Suspected or Proven Gram‐Positive Sepsis

Clinical and Translational Science
The objective of this study was to develop a population pharmacokinetic model for linezolid in hematooncological patients with sepsis, and to propose dosing optimization based on pharmacokinetic covariates that would lead to improved achievement of the ...
Alžběta Zavřelová, Sara Merdita, Pavel Žák, Jakub Radocha, Benjamin Víšek, Miriam Lánská, Jana Maláková, Pavel Michálek, Ondřej Slanař, Martin Šíma   +9 more
doaj   +1 more source

Crystal structure of (S)-5-(3-acetyl-5-chloro-2-ethoxy-6-fluorophenyl)-2-oxazolidinone

Acta Crystallographica Section E: Crystallographic Communications
The structure of (S)-5-(3-acetyl-5-chloro-2-ethoxy-6-fluorophenyl)-2-oxazolidinone, C13H13ClFNO4, at 100 K has monoclinic (P21) symmetry. The compound has a polymeric structure propagated by a screw axis parallel to the b axis with N—H...O hydrogen ...
Victor Li, Glenn P. A. Yap, Chaoying Ni
doaj   +1 more source

When First‐Line Therapies Fail: Surgical Site Infections and the Declining Antimicrobial Utility in a Resource‐Limited Nation

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
In Belize, a 7‐year nationwide study reveals a sharp rise in antimicrobial resistance in surgical infections. ESBL‐producing bacteria more than doubled to > 45%, with critical treatment gaps and geographic hotspots identified. Sentinel pan‐drug‐resistant cases and a correlation between antibiotic use and resistance underscore the urgent need for ...
Innocent E. Nwachukwu, Cary W. Rivera, Vivian M. Reyes, Diomar Salazar, Lydia Harris‐Thurton, Danladi C. Husaini   +5 more
wiley   +1 more source

Characterization of Multitrait Plant Growth‐Promoting Rhizobacteria From Opuntia ficus‐indica in Different Moroccan Climates

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The rhizosphere of Opuntia ficus‐indica from different Moroccan climates harbors diverse plant growth‐promoting bacteria with multiple beneficial traits. Selected isolates enhanced seed germination and seedling growth, highlighting their potential for sustainable agriculture in arid and semiarid environments.
Ilham Zouitane, Daniela Cristina Campana, Patrizia Cesaro, Nadia Massa, Giorgia Novello, Elisa Gamalero, Valeria Todeschini, Mohamed Ferioun, Khalid Derraz, Saad Ibnsouda Koraichi, Naïma El Ghachtouli, Guido Lingua   +11 more
wiley   +1 more source

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

The Chemical Record, Volume 26, Issue 6, June 2026.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source

3-[2-(2-Amino-1H-benzo[d]imidazol-1-yl)ethyl]-1,3-oxazolidin-2-one

IUCrData, 2016
In the title compound, C12H14N4O2, the benzimidazole ring is almost planar (r.m.s. deviation = 0.03 Å), with the fused ring system slightly folded at the shared atoms, with a dihedral angle of 3.4 (1)°.
Abdellatif Bouayyadi, Ahmed Moussaif, Abdelhalim Mesfioui, Mohammed Mzibri, Mohamed Saadi, Lahcen El Ammari   +5 more
doaj   +1 more source

Burn Wound Infections With Staphylococcus aureus: Clinical Characteristics and Risk Factors for Methicillin‐Resistant Strains

International Wound Journal, Volume 23, Issue 6, June 2026.
ABSTRACT This study aimed to systematically delineate the clinical characteristics and identify the key risk factors associated with methicillin‐resistant Staphylococcus aureus (MRSA) infections in burn patients, thereby informing targeted preventive measures and therapeutic strategies.
Xiaolan Hong, Shaobo Zhou, Qinghua Cai, Yuanyuan Cai, Zhaohong Chen, Wanting Zhao, Yongjian Ye, Xubo Dai   +7 more
wiley   +1 more source

Linezolid: The First Oxazolidinone Antimicrobial

Annals of Internal Medicine, 2003
Linezolid is the first of a new class of antimicrobial agents, the oxazolidinones, to be approved for clinical use in the United States and elsewhere. The drug is a totally synthetic compound, which lessens the likelihood of naturally occurring resistance mechanisms.
Paterson, David L., Pasculle, A. William, McCurry, Kenneth   +2 more
openaire   +6 more sources

Microwave-Assisted Condensation of Two Potential Antibacterial Pharmacophores (Sulfonamide and Oxazolidinone)

Engineering Proceedings
In recent years, microwave heating has become a widely used technique in organic synthesis. The reactions take place within a very short time, under mild conditions with high yields, and produce pure and selective compounds with fewer side reactions.
Radia Bouasla, Malika Berredjem
doaj   +1 more source