Results 21 to 30 of about 9,081 (170)

Linezolid-associated Hyponatremia in Section Guillain-Barré Syndrome Patients in Intensive Care unit: A Retrospective Analysis [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Guillain-Barré Syndrome (GBS) is a neurological disorder associated with ascending paralysis due to damage to the peripheral nerves by the immune system.
Shweta Suresh Naik, Mathangi Krishnakumar, S Mouleeswaran, VJ Ramesh   +3 more
doaj   +1 more source

Intracellular and in vivo activities of oxazolidinone drugs against Mycobacterium avium complex infection

Scientific Reports, 2023
The prevalence of Mycobacterium avium complex-pulmonary disease (MAC-PD) has become a growing concern worldwide, and current treatments involving macrolides (clarithromycin [CLR] or azithromycin), ethambutol, and rifampicin have limited success ...
Ju Mi Lee, Lee-Han Kim, Su-Young Kim, Byung Woo Jhun, Wonsik Lee, Sung Jae Shin   +5 more
doaj   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

Angewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang, Hsuan‐Hung Liao   +1 more
wiley   +2 more sources

Dynamic Operations in Macromolecular Data Storage

Angewandte Chemie, EarlyView.
With the exponential growth of digital data and the limitations of conventional silicon‐based storage and computing technologies, macromolecular data storage, the practice of encoding digital information within large, complex molecules like DNA or synthetic polymers, has emerged as a scalable and sustainable alternative to traditional digital ...
Jakub Ossowski, Oskar Affenberger, Jean‐François Lutz, Maria Nerantzaki   +3 more
wiley   +2 more sources

New oxazolidinone derivatives as antibacterial agents with improved activity [PDF]

, 2008
Background: Considerable efforts have been made in order to find new oxazolidinone-based antibacterial agents with improved biological profile. Objective: The purpose of this review is to highlight application patents on oxazolidinone-based antibacterial
BOTTA, Bruno, PORRETTA, Giulio Cesare, POCE, Giovanna, BIAVA, Mariangela, Giovanni Zappia   +4 more
core   +2 more sources

Crystal structure of 4-methyl-N-{(E)-methyl[(3aR,8aS)-2-oxo-3,3a,8,8a-tetrahydro-2H-indeno[1,2-d][1,3]oxazol-3-yl]-λ4-sulfanylidene}benzenesulfonamide

Acta Crystallographica Section E: Crystallographic Communications, 2015
The formulation that the title compound, C18H18N2O4S2, adopts is a zwitterionic core with the charge separated to the sulfilimine S and N atoms and is supported by the two different S—N bond distances about the sulfinimine N atom [1.594 (2) and 1.631 (2) 
Patrícia A. Pereira, Bruce C. Noll, Allen G. Oliver, Gustavo P. Silveira   +3 more
doaj   +1 more source

Florfenicol and oxazolidone resistance status in livestock farms revealed by short- and long-read metagenomic sequencing

Frontiers in Microbiology, 2022
Antibiotic resistance genes (ARGs) as a novel type of environmental pollutant pose a health risk to humans. Oxazolidinones are one of the most important antibiotics for the treatment of Gram-positive bacterial infections in humans.
Xue Yang, Tiejun Zhang, Chang-Wei Lei, Qin Wang, Zheren Huang, Xuan Chen, Hong-Ning Wang   +6 more
doaj   +1 more source

Syntheses and Crystal Structures of Three Chiral Oxazolidinones with Different Ring Conformations

Crystals, 2022
The preparation of new, enantiomerically pure, α-amino acids from easily available starting materials is an ongoing challenge in synthetic organic chemistry. Here, we describe the syntheses and crystal structures of three chiral oxazolidinone derivatives
Ester Soru, Grace Cairney, John M. D. Storey, William T. A. Harrison   +3 more
doaj   +1 more source

In Vitro Activities of Oxazolidinone Antibiotics Alone and in Combination with C-TEMPO against Methicillin-Resistant Staphylococcus aureus Biofilms

Antibiotics, 2023
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a global health concern. The propensity of MRSA to form biofilms is a significant contributor to its pathogenicity.
Audrey R. N. Ndukwe, Jilong Qin, Sandra Wiedbrauk, Nathan R. B. Boase, Kathryn E. Fairfull-Smith, Makrina Totsika   +5 more
doaj   +1 more source

New and old oxazolidinones: tedizolid vs. linezolid [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Tedizolid is a novel oxazolidinone that has been recently approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive pathogens, including MRSA.
Dekhnich A.V., Hachatryan N.N.
doaj