Results 21 to 30 of about 14,274 (205)

Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria

Molecules, 2020
The introductions of the bicyclic 4-nitroimidazole and the oxazolidinone classes of antimicrobial agents represented the most significant advancements in the infectious disease area during the past two decades.
Zhijun Zhuang, Dawei Wan, Jun Ding, Shijie He, Qian Zhang, Xiaomei Wang, Ying Yuan, Yu Lu, Charles Z. Ding, Anthony Simon Lynch, Anna M. Upton, Christopher B. Cooper, William A. Denny, Zhenkun Ma   +13 more
doaj   +1 more source

Florfenicol and oxazolidone resistance status in livestock farms revealed by short- and long-read metagenomic sequencing

Frontiers in Microbiology, 2022
Antibiotic resistance genes (ARGs) as a novel type of environmental pollutant pose a health risk to humans. Oxazolidinones are one of the most important antibiotics for the treatment of Gram-positive bacterial infections in humans.
Xue Yang, Tiejun Zhang, Chang-Wei Lei, Qin Wang, Zheren Huang, Xuan Chen, Hong-Ning Wang   +6 more
doaj   +1 more source

Asymmetric 1,3-dipolar cycloadditions of acrylamides [PDF]

, 2009
This critical review, which is relevant to researchers in synthetic organic chemistry, focuses on asymmetric 1,3-dipolar cycloadditions with acrylamides.
Kissane, Marie, Maguire, Anita R.
core   +1 more source

Crystal structure of 4-methyl-N-{(E)-methyl[(3aR,8aS)-2-oxo-3,3a,8,8a-tetrahydro-2H-indeno[1,2-d][1,3]oxazol-3-yl]-λ4-sulfanylidene}benzenesulfonamide

Acta Crystallographica Section E: Crystallographic Communications, 2015
The formulation that the title compound, C18H18N2O4S2, adopts is a zwitterionic core with the charge separated to the sulfilimine S and N atoms and is supported by the two different S—N bond distances about the sulfinimine N atom [1.594 (2) and 1.631 (2) 
Patrícia A. Pereira, Bruce C. Noll, Allen G. Oliver, Gustavo P. Silveira   +3 more
doaj   +1 more source

Syntheses and Crystal Structures of Three Chiral Oxazolidinones with Different Ring Conformations

Crystals, 2022
The preparation of new, enantiomerically pure, α-amino acids from easily available starting materials is an ongoing challenge in synthetic organic chemistry. Here, we describe the syntheses and crystal structures of three chiral oxazolidinone derivatives
Ester Soru, Grace Cairney, John M. D. Storey, William T. A. Harrison   +3 more
doaj   +1 more source

In Vitro Activities of Oxazolidinone Antibiotics Alone and in Combination with C-TEMPO against Methicillin-Resistant Staphylococcus aureus Biofilms

Antibiotics, 2023
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a global health concern. The propensity of MRSA to form biofilms is a significant contributor to its pathogenicity.
Audrey R. N. Ndukwe, Jilong Qin, Sandra Wiedbrauk, Nathan R. B. Boase, Kathryn E. Fairfull-Smith, Makrina Totsika   +5 more
doaj   +1 more source

New and old oxazolidinones: tedizolid vs. linezolid [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Tedizolid is a novel oxazolidinone that has been recently approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive pathogens, including MRSA.
Dekhnich A.V., Hachatryan N.N.
doaj  

P-Chiral phosphine oxide catalysed reduction of prochiral ketimines using trichlorosilane [PDF]

, 2003
Twelve P-chiral phosphine oxides were screened for their ability to act as a chiral Lewis base catalyst for the asymmetric hydrosilylation of ketimines, providing chiral amines in good conversion and yield, but relatively poor enantioselectivity (ee
Ghose, Henkel, Guizzetti, Jones, Iwasaki, Malkov, Malkov, Malkov, Matsumura, Wang, Wang, Zhou, Wang, Wang, Jones, Gautier, Gautier, Onomura, Pei, Pei, Liu, Sugiura, Bonsignore, Adams, Liu, Liu, Guillaneux, Girard, Bergin, Rajendran, Oshiki, Ellis   +31 more
core   +1 more source

Residue analyses and exposure assessment of the Irish population to nitrofuran metabolites from different food commodities in 2009–2010 [PDF]

, 2013
peer-reviewedAn exposure assessment to nitrofuran residues was performed for three human populations (adults, teenagers and children), based on residue analyses of foods of animal origin (liver, honey, eggs and aquaculture) covering the 2-year period ...
Conroy, Emma-Rose, Danaher, Martin, Gibney, Mike, O'Mahony, John, Radovnikovic, Anita   +4 more
core   +1 more source

Antibacterial Properties and Computational Insights of Potent Novel Linezolid-Based Oxazolidinones

Pharmaceuticals, 2023
The mounting evidence of bacterial resistance against commonly prescribed antibiotics warrants the development of new antibacterial drugs on an urgent basis.
M. Shaheer Malik, Shaikh Faazil, Meshari A. Alsharif, Qazi Mohammad Sajid Jamal, Jabir H. Al-Fahemi, Amrita Banerjee, Arpita Chattopadhyay, Samir Kumar Pal, Ahmed Kamal, Saleh A. Ahmed   +9 more
doaj   +1 more source