Results 31 to 40 of about 9,081 (170)
, 2019 Novel chiral imidazolium and pyridinium ionic liquids based on tartaric acid and 2-oxazolidinone were designed. Symmetrical dicationic ionic liquids based on tartaric acid have been synthesized and characterized.
Sagar P. Nehate (5642369) +4 more
core +1 more source
In Vivo Activity of LCB 01-0699, a Prodrug of LCB 01-0648, against Staphylococcus aureus
Molecules, 2017 LCB01-0648 is a novel oxazolidinone compound that shows potent antibacterial activities against most Gram-positive cocci, including the multi-drug resistant Staphylococcus aureus.
Sang-Hun Oh +7 more
doaj +1 more source
Antibacterial Properties and Computational Insights of Potent Novel Linezolid-Based Oxazolidinones
Pharmaceuticals, 2023 The mounting evidence of bacterial resistance against commonly prescribed antibiotics warrants the development of new antibacterial drugs on an urgent basis.
M. Shaheer Malik +9 more
doaj +1 more source
Oxazolidinone Antibiotics: Chemical, Biological and Analytical Aspects
, 2021 This review covers the main aspects concerning the chemistry, the biological activity and the analytical determination of oxazolidinones, the only new class of synthetic antibiotics advanced in clinical use over the past 50 years.
Angela Scala +3 more
core +1 more source
Crystal structure of (4R,5S)-4-methyl-3-methylsulfinyl-5-phenyl-1,3-oxazolidin-2-one
Acta Crystallographica Section E, 2014 The absolute structure of the chiral asymmetric indole precursor title compound, C11H13NO3S, was confirmed by refinement of the Flack and Hooft parameters and is that expected based on the starting materials for the synthesis. The phenyl group subtends a
Gustavo Pozza Silveira +2 more
doaj +1 more source
Facile Synthesis of Oxazolidinones as Potential Antibacterial Agents
ChemistryOpenAn efficient microwave‐assisted synthesis route for novel oxazolidinone analogues has been developed. The general synthesis of these compounds began with an L‐proline‐mediated three‐component Mannich reaction between commercially available 3‐fluoro‐4 ...
Secret P. Els +9 more
doaj +1 more source
Frontiers in Medicine, 2019 Tedizolid (TZD) is an oxazolidinone derivative which demonstrates bacteriostatic activity through inhibition of protein synthesis. We compared the efficacies of TZD and an earlier-generation oxazolidinone, linezolid (LZD), in an experimental murine model
Wessam Abdelhady +2 more
doaj +1 more source
Oxazolidinone-Mediated Sequence Determination of One-Bead One-Compound Cyclic Peptide Libraries
, 2018 A novel one-bead one-compound (OBOC) dual ring-opening/cleavage approach for cyclic peptide sequencing was developed. The method selectively modifies serine, cysteine, threonine, and/or glutamic acid to an oxazolidinone-derived moiety, thereby increasing
Heidi E. Elashal (5059340) +3 more
core +1 more source
Borylcyclopropanes: Synthetic Strategies and Applications
Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley +2 more sources
Molecules, 2023 Comparative chiral separations of enantiomeric pairs of four oxazolidinone and two related thio-derivatives were performed by capillary electrophoresis, using cyclodextrins (CDs) as chiral selectors.
Zoltán-István Szabó +5 more
doaj +1 more source