Results 51 to 60 of about 14,274 (205)

Novel oxazolidinones harbor potent in vitro activity against the clinical isolates of multidrug-resistant Mycobacterium tuberculosis in China

open access: yesFrontiers in Medicine, 2022
ObjectiveTo investigate the in vitro activities of five oxazolidinones in parallel against the reference strains of different mycobacterial species and clinical isolates of Mycobacterium tuberculosis (Mtb), and shed light on the differences in the ...
Chenqian Wang   +10 more
doaj   +1 more source

Reduction‐Controlled Tunable Synthesis of Covellite (CuS) Nanoparticles from Water‐Soluble Single‐Source Precursors

open access: yesSmall, EarlyView.
Amino acid‐derived Cu(II)‐dithiocarbamates were synthesized as water‐soluble single‐source precursors for low‐temperature hydrothermal decomposition toward covellite (CuS) nanoparticles. Their decomposition followed a reduction‐mediated pathway via Cu(I)‐dithiocarbamate intermediates, with the reduction step being rate‐limiting and readily tunable ...
Xiang Xu   +8 more
wiley   +1 more source

Development of a general, enantioselective organocatalytic Mukaiyama-Michael reaction with α,β-unsaturated aldehydes [PDF]

open access: yes, 2009
LUMO-lowering organocatalysis has been extended to promote the conjugate addition of S-alkyl and 1-pyrrolyl silylketene acetals to α,β-unsaturated aldehydes, yielding both, syn and anti Mukaiyama–Michael products with high levels of enantioselectivity ...
Borths, Christopher J.   +2 more
core   +1 more source

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

open access: yesThe Chemical Record, EarlyView.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source

Tedizolid Activity Against Clinical Mycobacterium abscessus Complex Isolates—An in vitro Characterization Study

open access: yesFrontiers in Microbiology, 2018
Mycobacterium abscessus complex consist of three rapidly growing subspecies: M. abscessus, M. massiliense, and M. bolletii. They are clinically important human pathogens responsible for opportunistic pulmonary and skin and soft tissue infections ...
Ying Wei Tang   +5 more
doaj   +1 more source

Synthesis of (−)-epibatidine [PDF]

open access: yes, 2014
An asymmetric synthesis to the dendrobatid alkaloid (−)-epibatidine has been described, featuring chiral resolution of both optically pure 7-azabicyclo[2.2.1]heptanecarboxylic acid, and subsequent transformations to (−)-epibatidine.
Chiang, Yu-Min, Chiou, Wen-Hua
core   +1 more source

Asymmetric Transformations of α,β‐Unsaturated Oxazolidinones Catalyzed by C2‐Symmetric Chiral Iron Triad Complexes

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
This review highlights the evolution of highly enantioselective oxazolidinone transformations enabled by C2‐symmetric ligands, with emphasis on chiral iron triad complexes as cost‐effective, environmentally benign alternatives to late‐transition‐metal catalysts.
Arthur David, Thierry Ollevier
wiley   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

open access: yesAngewandte Chemie, Volume 138, Issue 10, 2 March 2026.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh   +5 more
wiley   +2 more sources

Critical role of tedizolid in the treatment of acute bacterial skin and skin structure infections

open access: yesDrug Design, Development and Therapy, 2016
Olivia Ferrández,1,2 Olatz Urbina,1 Santiago Grau1,3 1Hospital Pharmacy, Hospital Universitari del Mar, Barcelona, Spain; 2Nursing Department, Universitat Pompeu Fabra, Barcelona, Spain; 3Medicine Department, Universitat Autònoma de ...
Ferrández O, Urbina O, Grau S
doaj  

In Vitro Activities of LCB 01-0648, a Novel Oxazolidinone, against Gram-Positive Bacteria

open access: yesMolecules, 2017
Oxazolidinones are a novel class of synthetic antibacterial agents that inhibit bacterial protein synthesis. Here, we synthesized and tested a series of oxazolidinone compounds containing cyclic amidrazone.
Sang-Hun Oh   +6 more
doaj   +1 more source

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