Results 11 to 20 of about 6,207 (176)

In-vitro Susceptibility of Linezolid and Teicoplanin in Methicillin-resistant Staphylococcus aureus by E-test

National Journal of Laboratory Medicine, 2023
Introduction: Staphylococcus aureus (S. aureus) is a ubiquitous pathogen causing various infections in humans. The emergence of drug resistance in S. aureus, especially methicillin resistance, has made treating these infections increasingly tricky, with ...
Thammina Meher Srisai Sudhavani, Nunsavathu Lakshmi, Chamalla Siva Kalyani, Burle Gowtham   +3 more
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(1R/S,7aS/R)-1-Benzyl-1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-hexahydro-oxazolo[3,4-a]pyridin-3-one

Molbank, 2023
An unexpected diastereoselective C-alkylation of a mefloquine derivative in up to 57% yield was the result of an attempted Williamson etherification of Boc-mefloquine.
Dawid J. Kucharski, Przemysław J. Boratyński   +1 more
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Tuberculosis patients with special clinical conditions treated with contezolid: three case reports and a literature review

Frontiers in Medicine, 2023
BackgroundContezolid is a novel oxazolidinone antibacterial agent, but there have been no reports of any pertinent clinical studies for the treatment of tuberculosis (TB).
Jun Wang, Liping Ma
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A Retrospective Study to Compare the Incidence of Hyponatremia after Administration between Linezolid and Tedizolid

Antibiotics, 2023
Linezolid (LZD) and Tedizolid (TZD) are oxazolidinone antibiotic for meticillin-resistant Staphylococcus aureus (MRSA). Severe hyponatremia after LZD administration have been reported.
Yuichi Shibata, Mao Hagihara, Nobuhiro Asai, Arufumi Shiota, Jun Hirai, Nobuaki Mori, Hiroshige Mikamo   +6 more
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Molecular characterization of florfenicol and oxazolidinone resistance in Enterococcus isolates from animals in China

Frontiers in Microbiology, 2022
Florfenicol is widely used for the treatment of bacterial infections in domestic animals. The aim of this study was to analyze the molecular mechanisms of florfenicol and oxazolidinone resistance in Enterococcus isolates from anal feces of domestic ...
Pingping Li, Pingping Li, Pingping Li, Pingping Li, Mengdi Gao, Mengdi Gao, Chunlin Feng, Chunlin Feng, Tielun Yan, Tielun Yan, Zhiqiong Sheng, Weina Shi, Weina Shi, Shuang Liu, Shuang Liu, Lei Zhang, Lei Zhang, Anqi Li, Anqi Li, Junwan Lu, Junwan Lu, Xi Lin, Xi Lin, Kewei Li, Kewei Li, Teng Xu, Qiyu Bao, Qiyu Bao, Caixia Sun, Caixia Sun   +29 more
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Linezolid-associated Hyponatremia in Section Guillain-Barré Syndrome Patients in Intensive Care unit: A Retrospective Analysis [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Guillain-Barré Syndrome (GBS) is a neurological disorder associated with ascending paralysis due to damage to the peripheral nerves by the immune system.
Shweta Suresh Naik, Mathangi Krishnakumar, S Mouleeswaran, VJ Ramesh   +3 more
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Intracellular and in vivo activities of oxazolidinone drugs against Mycobacterium avium complex infection

Scientific Reports, 2023
The prevalence of Mycobacterium avium complex-pulmonary disease (MAC-PD) has become a growing concern worldwide, and current treatments involving macrolides (clarithromycin [CLR] or azithromycin), ethambutol, and rifampicin have limited success ...
Ju Mi Lee, Lee-Han Kim, Su-Young Kim, Byung Woo Jhun, Wonsik Lee, Sung Jae Shin   +5 more
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Comparative Efficacies of Linezolid vs. Tedizolid in an Experimental Murine Model of Vancomycin-Resistant Enterococcal (VRE) Bacteremia

Frontiers in Medicine, 2019
Tedizolid (TZD) is an oxazolidinone derivative which demonstrates bacteriostatic activity through inhibition of protein synthesis. We compared the efficacies of TZD and an earlier-generation oxazolidinone, linezolid (LZD), in an experimental murine model
Wessam Abdelhady, Nagendra N. Mishra, Nagendra N. Mishra   +2 more
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Florfenicol and oxazolidone resistance status in livestock farms revealed by short- and long-read metagenomic sequencing

Frontiers in Microbiology, 2022
Antibiotic resistance genes (ARGs) as a novel type of environmental pollutant pose a health risk to humans. Oxazolidinones are one of the most important antibiotics for the treatment of Gram-positive bacterial infections in humans.
Xue Yang, Tiejun Zhang, Chang-Wei Lei, Qin Wang, Zheren Huang, Xuan Chen, Hong-Ning Wang   +6 more
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Crystal structure of 4-methyl-N-{(E)-methyl[(3aR,8aS)-2-oxo-3,3a,8,8a-tetrahydro-2H-indeno[1,2-d][1,3]oxazol-3-yl]-λ4-sulfanylidene}benzenesulfonamide

Acta Crystallographica Section E: Crystallographic Communications, 2015
The formulation that the title compound, C18H18N2O4S2, adopts is a zwitterionic core with the charge separated to the sulfilimine S and N atoms and is supported by the two different S—N bond distances about the sulfinimine N atom [1.594 (2) and 1.631 (2) 
Patrícia A. Pereira, Bruce C. Noll, Allen G. Oliver, Gustavo P. Silveira   +3 more
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