Results 11 to 20 of about 14,274 (205)
A new oxazolidinone antimicrobial [PDF]
American Journal of Health-System Pharmacy, 2014 Purpose. The mechanism of action, pharmacokinetics, pharmacodynamics, and clinical efficacy and safety of an investigational second-generation oxazolidinone are reviewed. Summary. Tedizolid is a protein synthesis inhibitor in clinical development for the
Childs, Lindsay M, +3 more
core +4 more sources
Antibiotics, 2023 Linezolid (LZD) and Tedizolid (TZD) are oxazolidinone antibiotic for meticillin-resistant Staphylococcus aureus (MRSA). Severe hyponatremia after LZD administration have been reported.
Yuichi Shibata +6 more
doaj +1 more source
Analysis of two pheromone-responsive conjugative multiresistance plasmids carrying the novel mobile optrA locus from Enterococcus faecalis [PDF]
, 2019 Background: The acquired optrA gene, which encodes a ribosomal protection protein of the ABC-F family, can confer cross-resistance to linezolid and florfenicol, posing a serious therapeutic challenge to both human and veterinary medicine.
Chen, Yu-Xia +7 more
core +1 more source
Frontiers in Microbiology, 2022 Florfenicol is widely used for the treatment of bacterial infections in domestic animals. The aim of this study was to analyze the molecular mechanisms of florfenicol and oxazolidinone resistance in Enterococcus isolates from anal feces of domestic ...
Pingping Li +29 more
doaj +1 more source
A Novel Synthesis of the Oxazolidinone Antithrombotic Agent Rivaroxaban
Molecules, 2014 A facile synthetic route of rivaroxaban has been developed. Using commercially available (R)-epichlorohydrin and bromobenzene as the starting materials, rivaroxaban was obtained in 39% overall yield using a Goldberg coupling as the key step.
Jianyong Yuan +5 more
doaj +1 more source
Linezolid-associated Hyponatremia in Section Guillain-Barré Syndrome Patients in Intensive Care unit: A Retrospective Analysis [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Guillain-Barré Syndrome (GBS) is a neurological disorder associated with ascending paralysis due to damage to the peripheral nerves by the immune system.
Shweta Suresh Naik +3 more
doaj +1 more source
Scientific Reports, 2023 The prevalence of Mycobacterium avium complex-pulmonary disease (MAC-PD) has become a growing concern worldwide, and current treatments involving macrolides (clarithromycin [CLR] or azithromycin), ethambutol, and rifampicin have limited success ...
Ju Mi Lee +5 more
doaj +1 more source
Fast pyrolysis of halogenated plastics recovered from waste computers [PDF]
, 2006 The disposal of waste computers is an issue that is gaining increasing interest around the world. In this paper, results from the fast pyrolysis in a fluidized bed reactor of three different waste computer monitor casings composed of mainly ...
Aracil I. +20 more
core +1 more source
An in vitro evaluation of the efficacy of tedizolid: implications for the treatment of skin and soft tissue infections [PDF]
, 2018 Skin and soft tissue infections (SSTI) are among the most commonly occurring infections and evidence suggests that these are increasing world-wide.
Aleryan, Muna +4 more
core +2 more sources
Frontiers in Medicine, 2019 Tedizolid (TZD) is an oxazolidinone derivative which demonstrates bacteriostatic activity through inhibition of protein synthesis. We compared the efficacies of TZD and an earlier-generation oxazolidinone, linezolid (LZD), in an experimental murine model
Wessam Abdelhady +2 more
doaj +1 more source