Results 91 to 100 of about 10,637 (203)

Structure-Antibacterial Activity Relationships of N-Substituted-(d-/l-Alaninyl) 1H-1,2,3-Triazolylmethyl Oxazolidinones

Scientia Pharmaceutica, 2018
Bacterial resistance towards the existing class of antibacterial drugs continues to increase, posing a significant threat to the clinical usefulness of these drugs.
Oludotun Adebayo Phillips, Edet Ekpenyong Udo, Roselyn Jennifer D’silva   +2 more
doaj   +1 more source

Synthesis and stereoselective oxidation of α-Thio-β- chloropropenyloxazolidin-2-ones [PDF]

, 2010
Investigation of the stereoselective reaction of α-thiopropanoyloxazolidin-2-ones with NCS to yield α-thio-β-chloropropenyloxazolidin-2-ones is described.
Kissane, Marie, Lawrence, Simon E., Maguire, Anita R., Murphy, Maureen   +3 more
core   +1 more source

Oxazolidinones

EMC - Maladies infectieuses, 2010
James C.M. Brust, Franklin D Lowy
  +4 more sources

Multicenter assessment of the linezolid spectrum and activity using the disk diffusion and Etest methods: report of the Zyvox® Antimicrobial Potency Study in Latin America (LA-ZAPS)

Brazilian Journal of Infectious Diseases
Linezolid was the first clinically applied member of the new antimicrobial class called the "oxazolidinones". These agents have a powerful spectrum of activity focussed against Gram-positive organisms including strains with documented resistances to ...
Charles H. Ballow, Douglas J. Biedenbach, Flavia Rossi, Ronald N. Jones   +3 more
doaj   +1 more source

Synthesis new heterocyclic compounds derived from 2-aminobenzothiazole and assessing their biological activities [PDF]

Caspian Journal of Environmental Sciences
This work involved two parts: the first part included synthesis of new Schiff bases from condensation of 2-aminobenzothiazole with different aldehydes in acidic medium, while and the second part included the synthesis of Oxazolidinones from reaction of ...
Raed Muslim Mhaibes, Rasha Kareem Khudhur, Mukalad A. Ramadhan, Mohammed Abdul-Mounther Othman   +3 more
doaj   +1 more source

Antimicrobial peptides as novel anti-tuberculosis therapeutics [PDF]

, 2016
"Available online 24 May 2016"Tuberculosis (TB), a disease caused by the human pathogen Mycobacterium tuberculosis, has recently joined HIV/AIDS as the world's deadliest infectious disease, affecting around 9.6 million people worldwide in 2014. Of those,
Agerberth, Ahsan, Andersson, Andersson, Andries, Aoki, Asaduzzaman, Balasubramanian, Bartolomeo, Bauer, Bayer, Bell, Bierbaum, Blaas, Bogatcheva, Bottger, Bray, Brogden, Brown, Brötz, Butler, Carroll, Center for Drug Evaluation and Research (CDER), Cervantes-Villagrana, Champion, Champion, Ciornei, Cohen, Corrales-Garcia, Courvalin, Diel, Directorate-General of the European Comission, Duplantier, Durr, Eckert, Ernst, European Commission, European Commission, European Commission, European Medicines Agency, Fattorini, Florence, Food and Drug Administration (FDA), Food and Drug Administration (FDA), Fox, Fox, Fox, Francisco Miguel Gama, Fratti, Fuertes, Gaspar, Gelperina, Ghobrial, Giehl, Giuliani, Gler, Global Alliance for TB Drug Development, Global Drug Facility, Goldstein, Gottler, Guirado, Gunther, Hancock, Hancock, Harper, Harris, Hmama, Horn, Hunter, International Conference on Harmonizarion Expert Working Group, Ishizaki, Islam, Jarlier, Jena, Jiang, Jin, João P. Silva, Kalita, Kaplan, Kapoor, Kaspar, Kayser, Khara, Kik, Kisich, Kusnadi, Kwok, Lan, Lax, Lax, Lee, Lee, Lehrer, Levy, Li, Li, Li, Limoli, Linde, Lunov, Makarov, Mansour, Mariappan, Marr, Matsuzaki, Matsuzaki, McGhan, Miller-Keane, Mily, Miteva, Mohanty, Molhoek, Mukherjee, Mygind, Médecins sans Frontières (MSF), Nagaoka, Nawrocki, Neyrolles, Nikonenko, Nizet, Nizet, Onyebujoh, Oren, Orme, Otvos, Padhi, Pandey, Pandey, Park, Patrzykat, Peschel, Peschel, Pethe, Pietiainen, Pokorny, Prideaux, Protopopova, Ramon-Garcia, Ramos, Ramos, Rathinakumar, Rivas-Santiago, Rivas-Santiago, Rivas-Santiago, Rosenfeld, Roy, Rubinchik, Rui Appelberg, Rutherfurd, Sanborn, Santos, Santos, Saravolatz, Schatz, Scheinpflug, Sensi, Shai, Shai, Sharma, Sharma, Shaw, Sherman, Shinnar, Silva, Somoskovi, Sosnik, Sosunov, Stehr, Steinstraesser, Stenger, Sterling, Sundararajan, Swietlow, Tabata, Tahlan, Tasneen, Tomioka, Toro, Torres-Juarez, Transparency Market Research, Uhlig, van der Does, Vilcheze, Vlieghe, Wallis, Wang, Wang, Welsh, Wenzel, Wiedemann, Wimley, World Health Organization, World Health Organization (WHO), World Health Organization (WHO), World Health Organization (WHO), World Health Organization (WHO), Xiong, Yamasaki, Yang, Yeaman, Zasloff, Zasloff, Zeitler, Zelezetsky, Zhang, Zhao, Zumla, Zumla, Zumla   +208 more
core   +1 more source

Antimicrobial activity of linezolid against Gram-positive cocci isolated in Brazil

Brazilian Journal of Infectious Diseases, 2001
The new oxazolidinone linezolid and other antimicrobial agents used to treat Gram-positive infections were tested against 1,585 Gram-positive cocci; 1,260 staphylococci and enterococci isolates from patients hospitalized in Brazilian hospitals, and 325 S.
Sader Helio S., Gales Ana C., Jones Ronald N.   +2 more
doaj  

New and old oxazolidinones: tedizolid vs. linezolid [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Tedizolid is a novel oxazolidinone that has been recently approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive pathogens, including MRSA.
Dekhnich A.V., Hachatryan N.N.
doaj  

A cohort study of the effectiveness of influenza vaccine in older people, performed using the United Kingdom general practice research database.

, 2004
BACKGROUND: The effectiveness of influenza vaccination against hospitalization and death can only ethically be assessed in observational studies. A concern is that individuals who are vaccinated are healthier than individuals who are not vaccinated ...
Cumberland, Phillippa, Cutts, Felicity T, Hall, Andrew J, Hodgson, Cathy R, Mangtani, Punam, Roberts, Jennifer A   +5 more
core   +1 more source

Cost-effectiveness of infant vaccination with RIX4414 (Rotarix) in the UK.

, 2009
This study estimated the cost-effectiveness of infant rotavirus vaccination with Rotarix in the UK, taking into account community rotavirus infections that do not present to the healthcare system.
Batty, A, Martin, A, Roberts, JA, Standaert, B   +3 more
core   +1 more source