A case report of seizure worsening after perampanel add-on to oxcarbazepine: possible role of metabolic interaction and pharmacogenetics [PDF]
ObjectiveTo investigate the factors contributing to increased seizure frequency in patients treated with a combination of oxcarbazepine (OXC) and perampanel.MethodsThe influence of the combined use of perampanel and oxcarbazepine on pharmacokinetics was ...
Xin Fang, Menglu Zhu, Lijiang Wang
doaj +2 more sources
Successful Treatment of Recurrent Painful Muscle Spasms After Total Hip Arthroplasty With Oxcarbazepine: A Case Report [PDF]
Painful muscle spasms are characterized by sudden onset of involuntary muscle contractions accompanying severe pain. The occurrence of painful muscle spasms after total hip arthroplasty (THA) is extremely rare in clinical practice.
Youhan Yang +3 more
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Reintroduction of oxcarbazepine after allergic reaction in two pediatric patients with epilepsy
Allergic reactions are common reasons for withdrawal of oxcarbazepine treatment in patients with epilepsy. However, some patients are not responsive to other antiseizure medications.
Lingyan Yu +4 more
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Determination of oxcarbazepine and its related substances using UHPLC method with UV detection [PDF]
A simple and rapid ultra - high performance liquid chromatographic (UHPLC) method for the separation and determination of oxcarbazepine and its related substances in tablets, was developed.
Žirojević Jelena +2 more
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Research reports using animal models of ischemic insults have demonstrated that oxcarbazepine (a carbamazepine analog: one of the anticonvulsant compounds) extends neuroprotective effects against cerebral or forebrain injury induced by ischemia and ...
Yang Hee Kim +9 more
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Evaluation of Antioxidant Effects of Antiepileptic Drugs in Adult Epileptic Patients: An Open Label, Non Randomised Interventional Study [PDF]
Introduction: Oxidative stress is one of the factors implicated in the pathogenesis of epilepsy. Various antiepileptic drugs can control seizures by several mechanisms that may involve reduction of oxidative stress.
B Swathi, D Aruna
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Oxcarbazepine Induced Maculopapular Rash - A Case Report [PDF]
Unlike carbamazepine, newer anti epileptic drug like oxcarbazepine, reports fewer side effects. In this report we describe a case of oxcarbazepine induced maculopapular rash probably happened because of a drug interaction with isoniazid, and a brief ...
Arunava Biswas +4 more
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Oxcarbazepine for Behavioral Disorders after Brain Injury: Factors Influencing Efficacy
Carbamazepine and oxcarbazepine are used for behavioral disorders following organic diseases. After severe acquired brain injury, patients may develop frontal symptoms.
Marco Pozzi +5 more
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Status epilepticus induced by hyponatremia as an adverse reaction to oxcarbazepine – case report [PDF]
We present a case of status epilepticus induced by hyponatremia as an adverse reaction to an antiepileptic drug. A 60 years old female was admitted to our department for partial seizures cluster activity with secondary generalization.
Corina Roman-Filip +4 more
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Oxcarbazepine-induced Steven–Johnson syndrome
Carbamazepine has been well documented to be associated with Steven–Johnson Syndrome (SJS). The newer anti-epileptic oxcarbazepine has not been demonstrated to be associated with this rare side effect except in some case reports. We present a case of SJS
Ganga Raju Godasi +2 more
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