Results 251 to 260 of about 25,431 (290)

Comparing the accuracy and efficiency of third generation DNA barcode sequencing: Oxford Nanopore Technologies versus Pacific Biosciences

open access: yes, 2022
Cuber P   +9 more
europepmc   +1 more source

Single‐Cell Omics Analysis of Human Basophils Reveals Two Transcriptionally Distinct Populations

open access: yesAllergy, Volume 81, Issue 6, Page 2059-2068, June 2026.
Integrated single‐cell transcriptomics and large‐scale immunophenotyping reveal the molecular landscape of human basophils. Circulating basophils comprise two transcriptionally distinct populations. A user‐friendly web resource enables interactive exploration of the generated data.
Sofia Papavasileiou   +13 more
wiley   +1 more source

Full-length 16S rDNA sequencing based on Oxford Nanopore Technologies revealed the association between gut-pharyngeal microbiota and tuberculosis in cynomolgus macaques. [PDF]

open access: yesSci Rep
Sawaswong V   +14 more
europepmc   +1 more source

A Refined Method for Fecal Microbiota Transplantation Using Nutella

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Fecal microbiota transplantation (FMT) in mice is an evolving research field, often employing oral gavage, which can be stressful and harmful for the animals and time‐consuming for technicians. Voluntary intake methods, such as delivery in Nutella, have successfully been used for drug administration in mice and may likewise be a promising tool
Ida W. Henriksen   +6 more
wiley   +1 more source

The Inflammatory Response in the Murine Ovalbumin‐Induced Skin Inflammation Model Is Robust Despite Major Gut Microbiota Differences

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Valid pre‐clinical animal models are essential for effective drug development in inflammatory skin diseases like atopic dermatitis. Most murine models exhibit low‐to‐moderate inflammatory responses with significant variability, undermining their validity and contributing to high drug attrition rates.
Ida Wang Henriksen   +5 more
wiley   +1 more source

Genome‐wide and gene‐specific DNA methylation across developmental stages in Pogonomyrmex californicus: A socially polymorphic ant

open access: yesInsect Molecular Biology, Volume 35, Issue 3, Page 232-245, June 2026.
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro   +4 more
wiley   +1 more source

A Near Telomere‐to‐Telomere Genome of Belamcanda chinensis Provides Insights Into Genome Evolution and the Biosynthesis of Characteristic Isoflavones

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 4285-4301, June 2026.
ABSTRACT Belamcanda chinensis is a non‐leguminous medicinal plant rich in bioactive isoflavones; however, the lack of a high‐quality reference genome has limited elucidation of its isoflavone biosynthetic and modification network. Here, we present the first near telomere‐to‐telomere genome assembly of B.
Yuan‐Yuan Wang   +10 more
wiley   +1 more source

Advances in Visualizing Cytosine Methylation and Allele‐Specific Epigenetic States in Tissue Context

open access: yesPathology International, Volume 76, Issue 6, June 2026.
The ICON method enables sequence‐specific, bisulfite‐free visualization of DNA methylation through chemical recognition of methylated cytosines. Following probe hybridization under mild denaturing conditions, methylation‐dependent interstrand complexes are stabilized by covalent crosslinking.
Sohei Kitazawa   +2 more
wiley   +1 more source

Third‐Generation Nanopore Sequencing for Post‐Transplant Chimerism Monitoring

open access: yesHLA, Volume 107, Issue 6, June 2026.
ABSTRACT Post‐transplant chimerism monitoring is a cornerstone of hematopoietic stem cell transplantation (HSCT) follow‐up, providing early and clinically actionable information on engraftment, graft rejection and disease relapse. Analytical strategies have progressively evolved from STR‐based assays towards more sensitive molecular approaches ...
Pascal Pedini   +7 more
wiley   +1 more source

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