Results 41 to 50 of about 335,229 (260)

Stabilization of unstable oxides

Bulletin of Materials Science, 1981
Easily oxidizable oxides, FeO, and MnO, are unstable in air but can be easily stabilized by small amounts of other oxides. Further these two unstable oxides stabilize each other very well. Such stabilized FeO and MnO provide easy and reproducible methods of preparing electronic ceramics that need such unstable valency states in them.
C E Deshpande, M N Sankarshana Murthy
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Thermochemical stability and nonstoichiometry of erbia-stabilized bismuth oxide [PDF]

Solid State Ionics, 1992
A phase study has been performed of high oxygen ion conducting erbia-stabilized bismutch oxide (1-x)Bi2O3·xEr2O3 (BE100X) using thermal analysis and X-ray powder diffraction. Investigation of the effect of a long-time (500 h) anneal of samples at 650°C in air revealed that the minimum amount of erbia needed to stabilize the high-temperature cubic ...
Kruidhof, H., Bouwmeester, H.J.M., de Vries, K.J., Gellings, P.J., Burggraaf, A.J.   +4 more
openaire   +2 more sources

HIF1α stabilization in hypoxia is not oxidant-initiated

eLife, 2021
Hypoxic adaptation mediated by HIF transcription factors requires mitochondria, which have been implicated in regulating HIF1α stability in hypoxia by distinct models that involve consuming oxygen or alternatively converting oxygen into the second messenger peroxide.
Amit Kumar, Manisha Vaish, Saravanan S Karuppagounder, Irina Gazaryan, John W Cave, Anatoly A Starkov, Elizabeth T Anderson, Sheng Zhang, John T Pinto, Austin M Rountree, Wang Wang, Ian R Sweet, Rajiv R Ratan   +12 more
openaire   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The role of endogenous hydratable phospholipids in enhancing the oxidative stability of tiger nut (Cyperus esculentus L.) oil

Food Chemistry: X
Tiger nut oil (TNO) is a promising oil due to its excellent oxidative stability. The simulated system was developed using stripped tiger nut oil (STNO) and hydratable phospholipids (HP) extracted from TNO to study HP's antioxidant role.
Run-Yang Zhang, Jing-Ru Jia, Chen Liu, Xiao-Shuang Cai, Peng-Xiao Chen, Hua-Min Liu, Wen-Xue Zhu   +6 more
doaj   +1 more source