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Asthma is a chronic inflammatory lung disease that results in airflow limitation, hyperreactivity, and airway remodeling. There is strong evidence that an imbalance between the reducing and oxidizing systems favoring a more oxidative state is present in asthma. Endogenous and exogenous reactive oxygen species, such as superoxide anion, hydroxyl radical,
Umit Murat Sahiner+5 more
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Clinical relevance of biomarkers of oxidative stress [PDF]
SIGNIFICANCE Oxidative stress is considered to be an important component of various diseases. A vast number of methods have been developed and used in virtually all diseases to measure the extent and nature of oxidative stress, ranging from oxidation ...
Ana Cipak Gasparovic+32 more
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Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress [PDF]
Oxidative stress plays an important role in the progression of vascular endothelial dysfunction. The two major systems generating vascular oxidative stress are the NADPH oxidase and the xanthine oxidase pathways. Allopurinol, a xanthine oxidase inhibitor,
George, Jacob, Struthers, Allan D.
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Recent years have seen an increased interest in the role of oxidative stress (OS) in pregnancy. Pregnancy inherently heightens susceptibility to OS, a condition fueled by a systemic inflam-matory response which culminates in an elevated presence of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in the circulatory system.
Konrad Grzeszczak+4 more
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Plasma total antioxidant capacity and peroxidation biomarkers in psoriasis [PDF]
Systemic biomarkers of oxidative stress can be relevant for assessment of psoriasis severity, for prediction of the outcome of therapy and of the development of comorbidities.
Cavaliere, Arturo+2 more
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Expression of Heterologous OsDHAR Gene Improves Glutathione (GSH)-Dependent Antioxidant System and Maintenance of Cellular Redox Status in Synechococcus elongatus PCC 7942. [PDF]
An excess of reactive oxygen species (ROS) can cause severe oxidative damage to cellular components in photosynthetic cells. Antioxidant systems, such as the glutathione (GSH) pools, regulate redox status in cells to guard against such damage ...
Beld, Joris+9 more
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Cytokinin response factor 6 represses cytokinin-associated genes during oxidative stress [PDF]
Cytokinin is a phytohormone that is well known for its roles in numerous plant growth and developmental processes, yet it has also been linked to abiotic stress response in a less defined manner.
Benkova, Eva+10 more
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Oxidative Stress in Aging [PDF]
Constant formation of free radicals mainly reactive oxygen species (ROS) is the main characteristic of all living systems which use oxygen for their basal metabolism. Primarily, ROS are considered an integral component of basic cell regulation and signaling pathways certainly, suppressing tumor progression which forms the basis of the most ...
Mohammad Abdollahi+3 more
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Measurement and clinical significance of biomarkers of oxidative stress in humans [PDF]
Oxidative stress is the result of the imbalance between reactive oxygen species (ROS) formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are relevant in the evaluation of the disease status and of the health-enhancing ...
Altieri, Fabio+2 more
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OXIDATIVE STRESS AND ENDOMETRIOSIS [PDF]
Little is known about the aetiology of endometriosis; however, in the presence of oxidative stress, reactive oxygen species might increase growth and adhesion of endometrial cells in the peritoneal cavity, leading to endometriosis and infertility. Within a study investigating persistent organic compounds and endometriosis, the authors evaluated the ...
Donald Armstrong+4 more
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