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Oxidative Stress and Hypertension [PDF]
Circulation Research, 2021 A link between oxidative stress and hypertension has been firmly established in multiple animal models of hypertension but remains elusive in humans. While initial studies focused on inactivation of nitric oxide by superoxide, our understanding of relevant reactive oxygen species (superoxide, hydrogen peroxide, and peroxynitrite) and how they modify ...
Kathy K. Griendling +5 more
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The NRF2, Thioredoxin, and Glutathione System in Tumorigenesis and Anticancer Therapies
Antioxidants, 2020 Cancer remains an elusive, highly complex disease and a global burden. Constant change by acquired mutations and metabolic reprogramming contribute to the high inter- and intratumor heterogeneity of malignant cells, their selective growth advantage, and ...
Morana Jaganjac +3 more
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CVD and Oxidative Stress [PDF]
Journal of Clinical Medicine, 2017 Nowadays, it is known that oxidative stress plays at least two roles within the cell, the generation of cellular damage and the involvement in several signaling pathways in its balanced normal state. So far, a substantial amount of time and effort has been expended in the search for a clear link between cardiovascular disease (CVD) and the effects of ...
Karla Cervantes Gracia +2 more
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Antioxidants, 2023 Aging is characterized by a number of hallmarks including loss of mitochondrial homeostasis and decay in stress tolerance, among others. Unicellular eukaryotes have been widely used to study chronological aging.
Anna Gröger +5 more
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Antioxidants, 2023 Non-alcoholic fatty liver disease (NAFLD) shows liver fat depots without alcohol consumption. NAFLD does not have specific drug therapies, with a healthy lifestyle and weight loss being the main approaches to prevent and treat NAFLD.
Maria Magdalena Quetglas-Llabrés +9 more
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Oxidative Stress in Keratoconus?
Investigative Opthalmology & Visual Science, 2011 The purpose of this study was to establish the alterations of oxidative stress-related markers in keratoconus (KC) corneas.A total of 6 healthy and 11 ectatic corneas (7 KC and 4 post-LASIK) were studied. Different oxidative stress-related markers were determined to assess their implication in the KC pathophysiology.
Arnal, Emma +4 more
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Oxidant Stress in Hemodialysis [PDF]
Nephron, 2000 Accessible online at: www.karger.com/journals/nef Prof. Claudio Ronco is Visiting Professor of Medicine at Albert Einstein College of Medicine and Director of the Renal Research Laboratory, Division of Nephrology and Hypertension at Beth Israel Medical Center and Renal Research Institute, New York.
GALLI, Francesco, Ronco C.
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Oxidative stress response: a proteomic view [PDF]
Expert Rev Proteomics 2, 6 (2005) 949-56, 2008 The oxidative stress response is characterized by various effects on a range of biologic molecules. When examined at the protein level, both expression levels and protein modifications are altered by oxidative stress. While these effects have been studied in the past by classic biochemical methods, the recent onset of proteomics methods has allowed the
arxiv +1 more source
Antioxidants, 2022 Non-alcoholic fatty liver disease (NAFLD) is a disorder characterized by the excessive accumulation of lipids in the liver parenchyma. To date, there is no effective pharmacological treatment against NAFLD.
Margalida Monserrat-Mesquida +11 more
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Oxidative Stress in Neurodegeneration [PDF]
Advances in Pharmacological Sciences, 2011 It has been demonstrated that oxidative stress has a ubiquitous role in neurodegenerative diseases. Major source of oxidative stress due to reactive oxygen species (ROS) is related to mitochondria as an endogenous source. Although there is ample evidence from tissues of patients with neurodegenerative disorders of morphological, biochemical, and ...
Harish C. Pant +2 more
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