Results 221 to 230 of about 44,664 (289)

Silicon‐Based Agent Attenuates Age‐Related Spermatogenesis Disorder

International Journal of Urology, EarlyView.
ABSTRACT Objectives The progressive decline in birth rates due to delayed marriage has become a significant issue in developed countries, with male spermatogenetic capabilities gradually declining with age. This study evaluated the effectiveness of a silicon‐based agent (Si‐based) that efficiently generates hydrogen in the body to improve spermatogenic
Sohei Kuribayashi, Shinichiro Fukuhara, Hiroaki Kitakaze, Go Tsujimura, Takahiro Imanaka, Norichika Ueda, Kentaro Takezawa, Hikaru Kobayashi, Ryoichi Imamura, Norio Nonomura   +9 more
wiley   +1 more source

Transcriptomic, proteomic and biochemical comparison of luminescent and non‐luminescent Keroplatinae larvae (Diptera: Keroplatidae)

Insect Molecular Biology, EarlyView.
Transcriptomic and proteomic comparison of luminescent O. fultoni and non‐luminescent Neoditomyia sp show that the substrate binding fraction (SBF) has a similar abundance of hexamerins and the presence of flavin‐dependent reductases. In addition to the high content of keroplatin, SBF also contains considerable amounts of riboflavin and displays ...
Jaqueline R. Silva, Gabriel F. Pelentir, Danilo T. Amaral, Cassius Stevani, Vadim R. Viviani   +4 more
wiley   +1 more source

LAG‐3+ Regulatory T Cells Suppress Effector Function of T Cells and Allow Their Proliferation Into Regulatory T Cells

Immunology, EarlyView.
LAG‐3+ regulatory T cells suppress the effector but not the proliferative response of naïve cognate antigen‐specific CD4+ T cells in vivo. The suppressed T cells display upregulation of immune checkpoints and downregulation of pro‐inflammatory pathways with enhanced TCR signaling and reduced oxidative metabolism.
Avijit Dutta, Shi‐Chuen Miaw, Tse‐Ching Chen, Chia‐Shiang Chang, Yu‐Lin Huang, Yung‐Chang Lin, Chun‐Yen Lin, Ching‐Tai Huang   +7 more
wiley   +1 more source

MHNfs: Prompting In-Context Bioactivity Predictions for Low-Data Drug Discovery. [PDF]

J Chem Inf Model
Schimunek J, Luukkonen S, Klambauer G.
europepmc   +1 more source

Optical spectropotentiometric resolution of the hemes of hydroxylamine oxidoreductase. Heme quantitation and pH dependence of Em

, 1993
Michael J. Collins, D.M. Arciero, Alan B. Hooper   +2 more
openalex   +1 more source

Pharmacovigilance‐Based Identification and Mechanistic Exploration of Periodontitis‐Related Drugs

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Background Periodontitis is a common chronic inflammatory disease. However, drug‐related risks and underlying molecular mechanisms remain underexplored from large real‐world data. Methods We first mined the US Food and Drug Administration Adverse Event Reporting System (FAERS) database to identify drugs disproportionately associated with ...
Wuda Huoshen, Junkai Xiong, Xunmi Ma, Heng Wang, Panyu Cheng, Xinyu Chen, Ge Shuai, Yi Chen, Xinyue Zhang, Chen Sun, Chunhui Li, Rui Shi   +11 more
wiley   +1 more source

Strain-resolved comparison of beef and draft cattle rumen microbiomes using single-microbe genomics. [PDF]

Anim Microbiome
Guan F, Liu J, Zhou L, Tong Q, Wu N, Tu T, Wang Y, Yao B, Luo H, Tian J, Huang H.   +10 more
europepmc   +1 more source

Relationship between the newly identified bile acid binder and bile acid oxidoreductases in human liver.

, 1990
Hajime Takikawa, Andrew Stolz, Yuichi Sugiyama, Hisako Yoshida, Masami Yamanaka, Neil Kaplowitz   +5 more
openalex   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

A Quinoxaline 1,4-Dioxide Activates DNA Repair Systems in <i>Mycobacterium smegmatis</i>: A Transcriptomic Study. [PDF]

Int J Mol Sci
Bekker OB, Galanova OO, Vatlin AA, Frolova SG, Shitikov EA, Bespiatykh DA, Klimina KM, Veselovsky VA, Ilyasov RA, Smirnova SV, Reznikova DA, Kochetkov NI, Maslov DA, Danilenko VN.   +13 more
europepmc   +1 more source