Results 211 to 220 of about 10,063 (262)
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2022
This chapter discusses the synthesis and properties of compounds with N-N bonds. It looks into the synthesis and reaction of hydrazines, hydrazides, hydrazones, diazo compounds, and azides. The N-N-containing functional groups undergo vital interconversions which have great synthetic value.
Patrick D. Bailey, Keith M. Morgan
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This chapter discusses the synthesis and properties of compounds with N-N bonds. It looks into the synthesis and reaction of hydrazines, hydrazides, hydrazones, diazo compounds, and azides. The N-N-containing functional groups undergo vital interconversions which have great synthetic value.
Patrick D. Bailey, Keith M. Morgan
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Bioconjugate Chemistry, 2015
Chemical reaction rates are generally decreased at lower temperatures. Here, we report that an oxime ligation reaction in water at neutral pH is accelerated by freezing. The freezing method and its rate effect on oxime ligation are systematically studied on a peptide model system, and applied to a larger chemokine protein, containing a single acetyl ...
Agten, Stijn M. +2 more
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Chemical reaction rates are generally decreased at lower temperatures. Here, we report that an oxime ligation reaction in water at neutral pH is accelerated by freezing. The freezing method and its rate effect on oxime ligation are systematically studied on a peptide model system, and applied to a larger chemokine protein, containing a single acetyl ...
Agten, Stijn M. +2 more
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Bacteriostatic Action of Oximes
Nature, 1948THE action of numerous inorganic and organic substances on the growth of bacteria has been investigated in the hope of demonstrating properties useful either in the laboratory for selective and enrichment methods for isolation, or clinically for the treatment of the diseases which they cause.
J D A, GRAY, R A, LAMBERT
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Oxime and Oxime Ether Derivatives of 1,4‐Benzothiazine Related to Oxiconazole
ChemMedChem, 2007AbstractThe synthesis, in vitro antifungal activity, and molecular docking experiments of some oxime and oxime ether derivatives of azole 1,4‐benzothiazine are reported herein, with the aim of evaluating the influence of a partially constrained scaffold that is structurally related to Oxiconazole and bearing the 1,4‐benzothiazine moiety, on the ...
MILANESE, Lara +5 more
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Canadian Journal of Biochemistry and Physiology, 1963
Concentrations in the blood of rabbits of 1,1′-trimethylene bis (4-formylpyridinium bromide) dioxime (TMB4), of 2-formyl-1-methylpyridinium chloride oxime (PAM Cl), and of 2-formyl-1-methylpyridinium methanesulphonate oxime (P2S) were measured at short intervals during the period immediately following intravenous or intramuscular injection.
E E, DUKE, C A, DECANDOLE
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Concentrations in the blood of rabbits of 1,1′-trimethylene bis (4-formylpyridinium bromide) dioxime (TMB4), of 2-formyl-1-methylpyridinium chloride oxime (PAM Cl), and of 2-formyl-1-methylpyridinium methanesulphonate oxime (P2S) were measured at short intervals during the period immediately following intravenous or intramuscular injection.
E E, DUKE, C A, DECANDOLE
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The Oximes and Organophosphate Poisoning
Archives of Pediatrics & Adolescent Medicine, 1962Since the insects began fighting back in 1947,1the war against them has demanded an increasingly diversified armamentarium, and the organic phosphate insecticides have played an important part in the battle. Unfortunately, this group of compounds, an outgrowth of wartime investigation of the chemically related nerve gases, are poisonous to man as well ...
L A, PAGE, H L, VERHAULST
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Structure–Activity relationships of oxime neurokinin antagonists: oxime modifications
Bioorganic & Medicinal Chemistry Letters, 2002A thorough SAR study of the oxime region of the dual NK(1)/NK(2) antagonist 1 revealed several modifications that result in potent dual antagonists. Follow up SAR studies on a second-generation scaffold demonstrate that certain polar groups on the oxime can improve the dual binding affinity to the subnanomolar range.
Gregory A, Reichard +8 more
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Oximes of Dialkylaminobutanediones
The Journal of Organic Chemistry, 1947G B, BACHMAN, D E, WELTON
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Unsaturated Oximes, XXX: Oximes as Sweeteners
Archiv der Pharmazie, 1991Bernard Unterhalt, Ute Dabringhaus
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