Results 1 to 10 of about 8,604 (195)
Photochemical Deracemization of 3‐Substituted Oxindoles [PDF]
Angewandte Chemie, 2023 AbstractRacemic 3‐substituted oxindoles were successfully converted into enantiomerically pure or enriched material (up to 99 % ee) upon irradiation at λ=366 nm in the presence of a chiral benzophenone catalyst (10 mol %). The photochemical deracemization process allows predictable editing of the stereogenic center at carbon atom C3.
Johannes Großkopf +2 more
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Azobenzene-Oxindole Photochromic Dyads. [PDF]
Angew Chem Int Ed EnglAbstractManipulation of molecular geometry using photoresponsive units is a powerful tool in supramolecular chemistry, smart materials, and photopharmacology. Current synthetic chemistry offers many responsive molecules that perform such a task.
Ovalle M, Doellerer D, Feringa BL.
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Preparation of spirocyclic oxindoles by cyclisation of an oxime to a nitrone and dipolar cycloaddition [PDF]
Beilstein Journal of Organic ChemistryOxindoles are an important class of compounds with significant biological activities. Spirocyclic derivatives are present in a variety of natural products.
Beth L. Ritchie +2 more
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Oxindole–benzothiazole hybrids as CDK2 inhibitors and anticancer agents: design, synthesis and biological evaluation [PDF]
BMC ChemistryIn the current study, molecular hybridization between the oxindole core and benzothiazole system through an acetohydrazide moiety was accomplished for the design of a new series of oxindole–benzothiazole hybrids 9a–r targeting CDK2 for cancer therapy ...
Heba T. Abdel-Mohsen
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Solvent controlled synthesis of spiro and nonspiro indolinones with aminonaphthoquinone and pyrazolone moieties [PDF]
Scientific ReportsThis study describes the design and synthesis of novel hybrid molecular architectures based on the privileged indolin-2-one (oxindole) scaffold. The research leverages a multi-component reaction strategy, employing isatins, 2-amino-1,4-naphthoquinone ...
Hamed Pezhman +3 more
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Results in Chemistry, 2023 Oxindole derivatives have been known to possess anticancer, antimicrobial, antiviral, antioxidative, and other pharmacological activities. A substantial group of oxindole compounds are studied as anticancer and antimicrobial agents.
Esra Köse +2 more
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Antioxidants, 2020 Recent studies demonstrate that 5-fluoro-2-oxindole inhibits neuropathic pain but the antinociceptive actions of this drug and its effects on the plasticity, oxidative and inflammatory changes induced by peripheral inflammation as well as on the effects ...
Alejandro Redondo +2 more
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Molecules, 2021 A synthetic route for the enantioselective construction of the tetracyclic spiro[indolizidine-1,3′-oxindole] framework present in a large number of oxindole alkaloids, with a cis H-3/H-15 stereochemistry, a functionalized two-carbon substituent at C-15 ...
Nihan Yayik +4 more
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Base-free enantioselective SN2 alkylation of 2-oxindoles via bifunctional phase-transfer catalysis
Beilstein Journal of Organic Chemistry, 2021 N-Protected oxindole derivatives of unprecedented malleability bearing ester moieties at C-3 have been shown to participate in enantioselective phase-transfer-catalysed alkylations promoted by ad-hoc designed quaternary ammonium salts derived from ...
Mili Litvajova +3 more
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Catalytic Enantioselective Fluorination of Oxindoles. [PDF]
ChemInform, 2005 AbstractFor Abstract see ChemInform Abstract in Full Text.
Yoshitaka, Hamashima +4 more
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