Results 171 to 180 of about 8,483 (210)

Hydrazine Derivatives as C-Centered Radical Precursors for C-C Bond Formation Reactions. [PDF]

Molecules
Lopat'eva ER, Krylov IB, Terent'ev AO.
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Sequential one-pot synthesis of N-sulfonyl spiroaziridine oxindoles from spiroepoxy oxindoles

Organic & Biomolecular Chemistry, 2021
A sequential one-pot direct strategy for N-sulfonyl spiroaziridine oxindoles has been developed from spiroepoxy oxindoles with excellent yields by regioselective amination of spiroepoxide and a subsequent ring enclosure reaction of amino alcohol.
Anurag Biswas, SK Abu Saleh, Atanu Hazra, Subhas Chandra Debnath, Saumen Hajra   +4 more
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Substituted oxindole—I

Tetrahedron, 1968
Abstract A series of oxindole derivatives substituted in the aromatic ring and their N-Me homologues has been prepared. The effects of position and nature of substituents on the IR, NMR and UV spectra have been investigated. Evidence is presented which indicates the presence of an intermolecular hydrogen bond in solutions of oxindole and certain N ...
A.H. Beckett, R.W. Daisley, J. Walker
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Asymmetric Decarboxylative Allylation of Oxindoles

Organic Letters, 2011
An asymmetric decarboxylative palladium-catalyzed allylation of alkyl- and aryl-substituted oxindoles has been developed, enabling the installation of an all-carbon quaternary chiral center at the oxindole 3-position in excellent yields and good to excellent enantioselectivity.
Franckevicius, Vilius, Cuthbertson, James D., Pickworth, Mark, Pugh, David S., Taylor, Richard J. K.   +4 more
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Enamino-oxindole HIV protease inhibitors

Bioorganic & Medicinal Chemistry Letters, 2012
We have designed and synthesized a series of HIV protease inhibitors (PIs) with enamino-oxindole substituents optimized to interact with the S2' subsite of the HIV protease binding pocket. Several of these inhibitors have sub-nanomolar K(i) and antiviral IC(50) in the low nM range against WT HIV and against a panel of multi-drug resistant (MDR) strains.
Michael, Eissenstat, Tanya, Guerassina, Sergei, Gulnik, Elena, Afonina, Abelardo M, Silva, Douglas, Ludtke, Hiroko, Yokoe, Betty, Yu, John, Erickson   +8 more
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Unexpected 7‐Methylation of Oxindoles.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Balázs Volk, Rita Kapiller-Dezs喃i, Gyula Simig   +2 more
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Synthesis of oxindoles and aza-oxindoles

2012
The aim of this Ph.D. work is to establish different approaches for the synthesis of oxindoles and aza-oxindoles. Oxindoles and aza-oxindoles are common and important structural motif in natural products and biologically active molecules. In this thesis, we report a robust, cheap, efficient, and high atom economic protocol for the synthesis of ...
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Diastereodivergent Synthesis of 3‐Spirocyclopropyl‐2‐oxindoles through Direct Enantioselective Cyclopropanation of Oxindoles

Chemistry – A European Journal, 2012
The direct organocatalytic asymmetric cyclopropanation reaction of oxindoles by employing oxindoles as C1 synthon and bromonitroolefins as a convenient C2 synthon is described.
Dou, X., Lu, Y.
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Oxindoles from Phalaris coerulescens

Phytochemistry, 1998
A phytochemical examination of various accessions of Phalaris coerulescens for the presence of toxic phenylethylamines, indoloamines and tetrahydro-β-carbolines revealed the presence of oxindoles previously not reported to occur in Phalaris species. One of the oxindoles, the structure of which was elucidated by spectroscopic methods, has not hitherto ...
Neil Anderton, Peter A. Cockrum, Steven M. Colegate, John A. Edgar, Kirsty Flower, Ivan Vit, Richard I. Willing   +6 more
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Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles

Bioorganic & Medicinal Chemistry Letters, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Edgar R, Wood, Lee, Kuyper, Kimberly G, Petrov, Robert N, Hunter, Philip A, Harris, Karen, Lackey   +5 more
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