Results 71 to 80 of about 28,231 (235)

Acute Abdomen in a Patient with Cancer Pain on Oxycodone

Case Reports in Medicine, 2011
Opioids are a mainstay of treatment for moderate to severe cancer pain. At present, oxycodone has fewer adverse effects compared to morphine and is widely used for cancer pain therapy.
Naomi Kishine, Atsunobu Tsunoda, Seiji Kishimoto, Tomohisa Shoko   +3 more
doaj   +1 more source

Cholestatic hepatitis as a possible new side-effect of oxycodone: a case report

Journal of Medical Case Reports, 2008
Introduction Oxycodone is a widely-used semisynthetic opioid analgesic that has been used for over eighty years. Oxycodone is known to cause side effects such as nausea, pruritus, dizziness, constipation and somnolence. As far as we are aware cholestatic
Ho Vincent, Stewart Maxwell, Boyd Peter
doaj   +1 more source

Oxycodone self-administration activates the mitogen-activated protein kinase/ mitogen- and stress-activated protein kinase (MAPK-MSK) signaling pathway in the rat dorsal striatum

Scientific Reports, 2021
To identify signaling pathways activated by oxycodone self-administration (SA), Sprague–Dawley rats self-administered oxycodone for 20 days using short—(ShA, 3 h) and long-access (LgA, 9 h) paradigms.
Christopher A. Blackwood, Michael T. McCoy, Bruce Ladenheim, Jean Lud Cadet   +3 more
doaj   +1 more source

Prescribed pharmaceutical alternatives initiative coinciding with reductions in unregulated street opioid use among young people who use drugs: An interrupted time series analysis

Addiction, EarlyView.
Abstract Background and aims In British Columbia, Canada, an initiative was implemented in 2020 to reduce overdose mortality by prescribing pharmaceutical opioids (primarily hydromorphone) as a substitute for the toxic unregulated drug supply. This study estimated changes in the level and trend of unregulated opioid use and non‐prescribed hydromorphone
Erica McAdam, Mohammad Karamouzian, Michael John Milloy, Carmen Verdicchio, Eric C. Sayre, Kanna Hayashi, Thomas Kerr, Kora DeBeck   +7 more
wiley   +1 more source

Methylenedioxymethamphetamine (MDMA)‐related fatal poisoning in Australia, 2016 to 2025: Trends, characteristics and toxicology

Addiction, EarlyView.
Abstract Aims To determine: (1) Population rates of fatal methylenedioxymethamphetamine (MDMA)‐related poisoning over the period 2016–2023, years with high closure rates in the National Coronial Information System (NDIS); (2) the case characteristics of known cases of fatal MDMA‐related poisoning, 2016–2025; and (3) whether there have been changes in ...
Shane Darke, Johan Duflou, Agata Chrzanowska, Michael Farrell, Julia Lappin, Amy Peacock   +5 more
wiley   +1 more source

Molecular mechanisms underlying the enhanced analgesic effect of oxycodone compared to morphine in chemotherapy-induced neuropathic pain.

PLoS ONE, 2014
Oxycodone is a μ-opioid receptor agonist, used for the treatment of a large variety of painful disorders. Several studies have reported that oxycodone is a more potent pain reliever than morphine, and that it improves the quality of life of patients ...
Karine Thibault, Bernard Calvino, Isabelle Rivals, Fabien Marchand, Sophie Dubacq, Stephen B McMahon, Sophie Pezet   +6 more
doaj   +1 more source

Oxycodone-related fatalities in the West of Scotland

, 2009
The intent of this study was to review fatalities involving oxycodone in the west of Scotland using a liquid chromatography-electrospray ionization-tandem mass spectrometry method developed for the determination of oxycodone and N- and O-demethylated ...
Anderson, R., Al-Asmari, A.I., Cooper, G.A.   +2 more
core   +1 more source

Oxycodone for Cancer Pain in Adult Patients [PDF]

, 2015
Clinical Question: Is oxycodone associated with greater efficacy and fewer adverse events compared with alternative analgesics for cancer pain? Bottom Line: Oxycodone was not associated with superior cancer pain relief or fewer adverse effects ...
Hilgart, J, Bennett, MI, Schmidt-Hansen, M   +2 more
core   +1 more source

Probable cychlorphine exposure in a patient with opioid use disorder: A case report

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Cychlorphine is an emerging synthetic opioid with limited clinical data. Methods We describe a patient's reported cychlorphine use and its's clinical effects. Results Thirty‐five years old male with opioid use disorder reported purchasing cychlorphine online.
Manroop Bal, Nimna Mendis, Melissa Bennett, David Kinniburgh, Jeremy Weleff   +4 more
wiley   +1 more source

Impact of individualized opioid protocols on post-cesarean discharge prescriptions. [PDF]

Pregnancy (Hoboken)
Abstract Introduction Consensus on optimal prescribing of opioids at discharge following cesarean delivery remains limited. Since inpatient opioid use is a strong predictor of outpatient need, individualized approaches may improve prescribing accuracy.
Freeman SW, Mhatre M, Li MJ, Beard ME, Ludwick L, Lekshmi D, Ramos SZ.   +6 more
europepmc   +2 more sources