Results 91 to 100 of about 22,050 (201)

Emergency Department Triage Nurses' Scope of Practice: An Observational Study

Journal of Clinical Nursing, Volume 35, Issue 9, Page 3942-3958, September 2026.
ABSTRACT Aim To explore emergency department triage nurses' scope of practice and activities related to their triage role and management of patients located in emergency department waiting areas. Design Exploratory, descriptive, observational study using naturalistic decision making.
Julie Considine, Elizabeth Oldland, Judy Currey, Philippa Blencowe, Katrina Maybury, Leanne Stella, Amy Pearson, Paul Buntine, Kate Curtis   +8 more
wiley   +1 more source

From cramming to binge‐watching: Integrating documentary‐based assessment into a pharmacology and toxicology curriculum—a qualitative study

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2474-2486, August 2026.
Abstract Aims In the context of pharmacology and toxicology education, there is a growing shift toward programmatic assessment models that prioritize longitudinal learning, reflection and development of higher‐order cognitive skills. As part of this transition, we are exploring alternative and more meaningful forms of assessment. This qualitative study
Narin Akrawi, Heleen van der Sijs, Floor van Rosse   +2 more
wiley   +1 more source

Inbred rat heredity and sex affect oral oxycodone self-administration and augmented intake in long sessions: correlations with anxiety and novelty-seeking.

PLoS ONE
Oxycodone abuse frequently begins with prescription oral oxycodone, yet vulnerability factors (e.g. sex, genetics) determining abuse are largely undefined.
Burt M Sharp, Shuangying Leng, Jun Huang, Caroline Jones, Robert W Williams, Hao Chen   +5 more
doaj   +1 more source

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2624-2635, August 2026.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins, Alan Wells, Nimish Patel, Nicole Muttera, Mattia Trunfio, Alessandra Manca, Amedeo De Nicolò, Micol Ferrara, Stefano Bonora, Jessica Cusato, Alice Palermiti, Antonio D'Avolio, Marissa Borochoff, Patricia K. Riggs, Elizabeth Hastie, Rabia S. Atayee, Stephanie Solso, Cheryl Dullano, Vanessa Gomez‐Moreno, Tara Tenenbaum, Robert Deiss, Davey M. Smith, Antoine Chaillon, Sara Gianella   +23 more
wiley   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2682-2692, August 2026.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2693-2700, August 2026.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis, Johanna E. Vriezekolk, Frédérique H. C. Bollen, Dirk E. Schrander, Arnt F. A. Schellekens, Bart J. F. van den Bemt   +5 more
wiley   +1 more source

Mortality Trend in Patients With Heart Failure and Psychoactive Substance Abuse in the United States—Pre‐ and Post‐COVID‐19 Pandemic Perspective (1999−2023)

Clinical Cardiology, Volume 49, Issue 8, August 2026.
From 1999 to 2023, national HF‐substance abuse‐related mortality rates in adults rose over 10‐fold, disproportionately affecting males, older adults, and NH White and NH Black populations. Geographically, nonmetropolitan areas and the Midwestern/Northwestern regions saw the highest burden, signaling an urgent need for integrated cardiovascular and ...
Emad Uddin Sajid, Ayesha Irfan, Muhammad Kashan, Syed Rayyan Ahmed, Muhammad Hasnain Azeem, Tooba Ali, Mabel Waqar, Muneeba Khan, Erum Shahzadi Malik, Md Ariful Haque   +9 more
wiley   +1 more source

Oxycodone regulates incision-induced activation of neurotrophic factors and receptors in an acute post-surgery pain rat model

Journal of Pain Research, 2018
Baowen Liu, Yi Liu, Ningbo Li, Jin Zhang, Xianwei Zhang Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Background: Oxycodone, which is one of the most commonly used ...
Liu BW, Liu Y, Li NB, Zhang J, Zhang XW
doaj  

Trends and Characteristics of Opioid Use During Pregnancy Between 2010 and 2023: A French Nationwide Drug Utilization Study

European Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background While opioid use during pregnancy has raised concerns worldwide, population‐based data in Europe remain limited. In France, little is known about opioid use in the context of pregnancy. Methods We conducted a nationwide drug utilization study using the French EPI‐MERES Registry, derived from the National Health Data System (SNDS ...
Laurent Chouchana, Philippe Herlemont, Hugo Jourdain, Sara Miranda, Mahmoud Zureik, Rosemary Dray‐Spira   +5 more
wiley   +1 more source

The Combination of Buprenorphine and Pregabalin in the Management of Peripheral Neuropathic Pain: A Phase IV, Randomized, Double‐Blind and Placebo‐Controlled Clinical Trial

European Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background Pharmacological combinations are commonly used for treating refractory neuropathic pain, although supporting evidence is lacking. Gabapentinoid‐opioid combination is one of the most studied; however, their efficacy is inconsistent across clinical trials.
Larissa I. Moreira, Pedro N. Martins, Manoel J. Teixeira, Daniel C. de Andrade, Gabriel T. Kubota   +4 more
wiley   +1 more source