Results 111 to 120 of about 28,231 (235)

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

Experimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin, Jean‐Christophe Lagacé, Mathil Ruel, Ahmed Ghachem, Guillaume Léonard, Eleonor Riesco, Mathew Piasecki, Jamie S. McPhee, Isabelle J. Dionne   +8 more
wiley   +1 more source

Is There A Problem with Oxycodone? [PDF]

Journal of Pain and Symptom Management, 2008
Simon, Challand, Katie, Frew, Claud, Regnard   +2 more
openaire   +2 more sources

Prolonged-release oxycodone/naloxone improves anal sphincter relaxation compared to oxycodone plus macrogol 3350

, 2017
BACKGROUND: Opioid analgesics inhibit anal sphincter function and contribute to opioid-induced bowel dysfunction (OIBD). However, it is unknown whether the inhibition can be reduced by opioid antagonism with prolonged-release (PR) naloxone and how this ...
Gregersen, Hans, Brock, Christina, Brock, Christina; id_orcid, Hans Gregersen, Grønlund, Debbie, Drewes, Asbjørn; id_orcid, Christina Brock, Drewes, Asbjørn Mohr; id_orcid, Liao, Donghua, Donghua Liao, Jakob Lykke Poulsen, Asbjørn Mohr Drewes, Klaus Krogh, Krogh, K., Debbie Grønlund, Drewes, Asbjørn Mohr, Poulsen, Jakob Lykke; id_orcid, Poulsen, Jakob Lykke, Krogh, Klaus   +18 more
core   +1 more source

The Effect of Perioperative Video Interventions on Postoperative Pain Control: A Systematic Review

Acta Anaesthesiologica Scandinavica, Volume 71, Issue 1, January 2027.
ABSTRACT Introduction Postoperative pain is a major cause of suffering and is linked to serious complications, including delayed wound healing, increased cardiovascular risk, delayed rehabilitation, and chronic postsurgical pain. Modifiable psychological factors influence pain outcomes, and preliminary evidence suggests video interventions can reduce ...
Adam Danielsson, Sana Asif, Alexandra Forsberg, Miklós Lipcsey, Eva Kosek, Martin F. Bjurström   +5 more
wiley   +1 more source

Different effects of oxycodone and remifentanil in patients undergoing ultrasound-guided percutaneous radiofrequency ablation of hepatic cancer: a randomized trial

, 2019
Junbei Wu1,* Yunhong Lu2,* Xiaofei Cao11Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China; 2Department of Anesthesiology, The Second Affiliated Hospital of Nanjing Medical ...
Wu J, Cao X, Lu Y
core  

Prophylactic vaccination protects against the development of oxycodone self-administration

, 2017
Abuse of prescription opioids is a growing public health crisis in the United States, with drug overdose deaths increasing dramatically over the past 15 years. Few preclinical studies exist on the reinforcing effects of oxycodone or on the development of
Yanabel Grant, Jacques D. Nguyen, Candy S. Hwang, Kim D. Janda, Michael A. Taffe   +4 more
core   +1 more source

A Systematic Review of Complications Following Elective Foot and Ankle Surgery

Journal of Foot and Ankle Research, Volume 19, Issue 4, December 2026.
ABSTRACT Introduction Complications following elective foot and ankle surgery are a significant source of morbidity and may impair recovery. Evidence is often procedure specific, limiting a broader understanding. This review aimed to synthesize complication profiles, risk factors, and mitigation strategies across elective procedures.
Lia Spencer, Connor Phillips, Sifat Alam, Kit Ferguson, Richard Feinn, Douglas McHugh, Ewan Kannegieter   +6 more
wiley   +1 more source

Predator scent stress reduces oxycodone self-administration and the nucleus accumbens dopamine response to oxycodone in female rats

Addiction Neuroscience
Post-traumatic stress disorder (PTSD) develops in a sub-population of people exposed to trauma and is highly comorbid with opioid use disorder (OUD). The neurobiology of comorbid PTSD+OUD, especially with respect to sex differences, is poorly understood.
Courtney S. Wilkinson, Siya Bhutani, Wonn Pyon, Marek Schwendt, Lori A. Knackstedt   +4 more
doaj   +1 more source

Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice

, 2019
[[abstract]]Oxycodone, a widely prescribed and very potent oral opioid analgesic agent, is highly addictive and has many side effects, including troublesome constipation.
Yang, PP;Yeh, TK;Loh, HH;Law, PY;Wang, Y;Tao, PL
core   +1 more source

Patient Experiences of Chronic Low Back Pain: Development of a Conceptual Model Based on a Targeted Literature Review and Qualitative Patient Interviews

Musculoskeletal Care, Volume 24, Issue 4, December 2026.
ABSTRACT Purpose Chronic low back pain (CLBP) is a persistent, debilitating condition. The United States (US) Food and Drug Administration Patient‐Focused Drug Development Guidance recommends using patient‐reported outcome (PRO) measures to assess pain and function in clinical trials and document content validity of the measures based on patient ...
Ekin Seçinti, Brittany Klooster, Rebecca Robinson, Madison C. Bernstein, Madeline Tallarico, Kaitlin Chatterton, Adriana Voci, Daniella Olonilua, Samantha R. Linton, Leighann Litcher‐Kelly, Marcia M. Mellado Lagarde, Linda A. Wietecha, John Markman   +12 more
wiley   +1 more source