Current and new concepts in the diagnosis and management of diabetic macular oedema [PDF]
Diabetic macular oedema, which can cause rapid visual deterioration, may not have early warning signs at times. Assessment of diabetic retinal complications is made chiefly by clinical examination combined with optical coherence tomography (OCT) and ...
Jyothi, Sreedhar
core +7 more sources
Proteomics Analysis of R-Ras Deficiency in Oxygen Induced Retinopathy. [PDF]
Vähätupa M +5 more
europepmc +2 more sources
The Antiangiogenic Effect and Ocular Pharmacology of Novel Modified Nonsteroidal Anti-Inflammatory Drugs in the Treatment of Oxygen-Induced Retinopathy. [PDF]
Huang W +4 more
europepmc +2 more sources
Maternally expressed gene 3 regulates retinal neovascularization in retinopathy of prematurity
The mouse model of oxygen induced retinopathy is suitable for the study of various retinal neovascularization diseases, including retinopathy of prematurity.
Yu Di +5 more
doaj +1 more source
Whether long non-coding RNA myocardial infarction-associated transcript is involved in oxygen-induced retinopathy remains poorly understood. To validate this hypothesis, we established a newborn mouse model of oxygen-induced retinopathy by feeding in an ...
Yu Di, Yue Wang, Xue Wang, Qing-Zhu Nie
doaj +1 more source
Hyperoxia Inhibits Proliferation of Retinal Endothelial Cells in a Myc-Dependent Manner
Oxygen supplementation is necessary to prevent mortality in severely premature infants. However, the supraphysiological concentration of oxygen utilized in these infants simultaneously creates retinovascular growth attenuation and vasoobliteration that ...
Charandeep Singh +5 more
doaj +1 more source
Matrix metalloproteinase-9 and vascular endothelial growth factor expression change in experimental retinal neovascularization [PDF]
AIM: To investigate the signal transduction mechanism of matrix metalloproteinase-9 (MMP-9) mediated- vascular endothelial growth factor (VEGF) expression and retinal neovascularization (RNV) in oxygen-induced retinopathy (OIR) model.
Yu Di, Qing-Zhu Nie, Xiao-Long Chen
doaj +1 more source
Indomethacin Improves Oxygen-Induced Retinopathy in the Mouse [PDF]
Retinopathy of prematurity is a disease commonly affecting extremely premature babies. Indomethacin is widely used in the perinatal period. The goal of the present study was to test the hypothesis that indomethacin will improve retinopathy in a mouse model when administered during the period of injury (hyperoxia exposure) to the developing retinal ...
B N, Nandgaonkar +3 more
openaire +2 more sources
Prevalence of visual impairment and severity of diabetic retinopathy in various ethnic groups in the UK [PDF]
Diabetic Retinopathy (DR) is a leading cause of visual impairment (VI) in the working population. Minor ethnic groups are at increased risk of diabetes.
Gupta, Bhaskar
core +7 more sources
Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
Edema stemming from leaky blood vessels is common in eye diseases such as age-related macular degeneration and diabetic retinopathy. Whereas therapies targeting vascular endothelial growth factor A (VEGFA) can suppress leakage, side-effects include ...
Ross O Smith +7 more
doaj +1 more source

