Results 61 to 70 of about 105,653 (308)

A mechanistic study on the phototoxicity of atorvastatin: singlet oxygen generation by a phenanthrene-like photoproduct [PDF]

open access: yes, 2009
Atorvastatin calcium (ATV) is one of the most frequently prescribed drugs worldwide. Among the adverse effects observed for this lipid-lowering agent, clinical cases of cutaneous adverse reactions have been reported and associated with photosensitivity ...
IESCE, MARIA ROSARIA   +4 more
core   +1 more source

Interlaboratory Study of Hydrophilic-Oxygen Radical Absorbance Capacity, a Method for Measuring Antioxidant Capacity

open access: yesNippon Shokuhin Kagaku Kogaku Kaishi, 2010
本研究では,AOAC Internationalの基準に基づき,代表的な抗酸化物質を用いて抗酸化能測定法であるH-ORAC法の室間共同試験を行い,精度の調査を行った.室間共同試験には5種((+)-カテキン,Trolox, trans-フェルラ酸,ヘスペレチン,コーヒー酸)の抗酸化物質溶液および粉末を用いた.その結果,RSDrは溶液試料で5.9~13.2%,粉末試料で5.4~10.4%であり,RSDRは溶液試料で16.2~61.4%,粉末試料で16.9~33.2%であった.Trolox検量線の上限濃度である50μMから算出したHorRat値は溶液試料で1.48~5.62,粉末試料で1.54~3.03であり,本室間共同試験によって妥当性が確認されたとは言い難かった.室間再現性低下の要因として ...
Jun Watanabe   +4 more
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The Galloyl Catechins Contributing to Main Antioxidant Capacity of Tea Made from Camellia sinensis in China

open access: yesThe Scientific World Journal, 2014
Total polyphenol content, catechins content, and antioxidant capacities of green, dark, oolong, and black teas made from Camellia sinensis in China were evaluated. The total polyphenol content of 20 samples of tea was in the range of 7.82–32.36%.
Chunjian Zhao   +3 more
doaj   +1 more source

A Novel Antioxidant Phenyl Disaccharide from Populus tremula Knotwood

open access: yesMolecules, 2007
The complete characterization of two compounds obtained from the acetoneextract of Populus tremula knotwood has been was achieved using LC-DAD-MS,MS/MS, IR and NMR.
Bjarne Holmbom   +5 more
doaj   +1 more source

The Effect of Perilla frutescens extract on the oxidative stability of model food emulsions [PDF]

open access: yes, 2014
The polyphenolic profile of leaves and stalks of Perilla frutescens, was assessed as a source of natural antioxidants. The amount of caffeic and rosmarinic acids, determined by high-performance liquid chromatography (HPLC), were 0.51 mg/g dry weight ...
Almajano, Maria P.   +4 more
core   +3 more sources

The ORAC (oxygen radical absorbance capacity) index does not reflect the capacity of antioxidants to trap peroxyl radicals

open access: yesRSC Advances, 2015
We demonstrate from kinetic studies that under the experimental conditions proposed for the ORAC protocol, ORAC values do not correlate with the capacity of antioxidants to trap peroxyl radicals (ROO˙), suggesting a dominant role of alkoxyl radicals (RO˙) in the assay.
Dorta, E.   +7 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Comparative Study on Phenolic Content, Antioxidant Activity and Anti-Inflammatory Capacity of Aqueous and Ethanolic Extracts of Sorghum in Lipopolysaccharide-Induced RAW 264.7 Macrophages

open access: yesAntioxidants, 2020
Sorghum is an important cereal with diverse phenolic compounds that have potential health promoting benefits. The current study comparatively characterized the phenolic contents of two novel black-seeded sorghum lines (SC84 and PI570481) using different ...
Shan Hong   +6 more
doaj   +1 more source

Enzymatic Activities and Gene Transcript Levels Associated with the Augmentation of Antioxidant Constituents during Drought Stress in Lettuce

open access: yesHorticulturae, 2021
Efficient cultivation methods were investigated to promote the branding of products in plant factories. Moderate stress can enhance plant constituents that are beneficial for human health, without reducing yield.
Ryohei Koyama   +4 more
doaj   +1 more source

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