Results 31 to 40 of about 9,386 (216)

Detoxification Cytochrome P450s (CYPs) in Families 1–3 Produce Functional Oxylipins from Polyunsaturated Fatty Acids

open access: yesCells, 2022
This manuscript reviews the CYP-mediated production of oxylipins and the current known function of these diverse set of oxylipins with emphasis on the detoxification CYPs in families 1–3.
Jazmine A. Eccles, William S. Baldwin
doaj   +1 more source

Oxylipins as Potential Regulators of Inflammatory Conditions of Human Lactation

open access: yesMetabolites, 2022
Chronic low-grade inflammation can be associated with obesity or subclinical mastitis (SCM), which is associated with poor infant growth in low- to middle-income country settings.
Rachel E. Walker
doaj   +1 more source

Deciphering OPDA Signaling Components in the Momilactone-Producing Moss Calohypnum plumiforme

open access: yesFrontiers in Plant Science, 2021
Jasmonic acid (JA) and its biologically active form jasmonoyl-L-isoleucine (JA-Ile) regulate defense responses to various environmental stresses and developmental processes in plants.
Hideo Inagaki   +24 more
doaj   +1 more source

Therapeutic Potential of Plant Oxylipins

open access: yesInternational Journal of Molecular Sciences, 2022
For immobile plants, the main means of protection against adverse environmental factors is the biosynthesis of various secondary (specialized) metabolites. The extreme diversity and high biological activity of these metabolites determine the researchers’ interest in plants as a source of therapeutic agents.
Tatyana Savchenko   +3 more
openaire   +2 more sources

Metabolic change of oxylipin pathway in cold responses of chickpea plants [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2016
Oxylipins the products of fatty acid oxidation, to acclimate biotic and abiotic stresses. In this study, we evaluate the effects of cold stress by measuring manlodialdehyde (as membrane damage index), the activity of lipoxygenase (LOX) and allene oxide ...
Reza Maali Amiri   +2 more
doaj   +1 more source

Temperature and time-dependent effects of delayed blood processing on oxylipin concentrations in human plasma. [PDF]

open access: yes, 2019
BACKGROUND:Oxidized derivatives of polyunsaturated fatty acids, collectively known as oxylipins, are labile bioactive mediators with diverse roles in human physiology and pathology.
Gibson, Robert A   +8 more
core   +1 more source

ALOX15‐Derived Oxylipins Attenuate Macrophage Inflammatory Signaling Via a Gαq–PLC–PKC Pathway [PDF]

open access: yesFASEB J
ALOX15 expression and its downstream oxylipins, including 12‐HETE and 13‐HODE, are induced in intestinal epithelial and lamina propria immune cells during the early and middle phases of experimental colitis. These endogenous lipid mediators suppress lipopolysaccharide‐induced TNF‐α and IL‐6 production in macrophages without affecting cell viability ...
Hilman A   +4 more
europepmc   +2 more sources

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

open access: yes, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P   +11 more
core   +1 more source

The Oxylipin Pathway in Arabidopsis [PDF]

open access: yesThe Arabidopsis Book, 2002
Oxylipins are acyclic or cyclic oxidation products derived from the catabolism of fatty acids which regulate many defense and developmental pathways in plants. The dramatic increase in the volume of publications and reviews on these compounds since 1997 documents the increasing interest in this compound and its role in plants.
Robert A, Creelman, Rao, Mulpuri
openaire   +2 more sources

Soluble Epoxide Hydrolase Derived Linoleic Acid Oxylipins, Small Vessel Disease Markers, and Neurodegeneration in Stroke

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Cerebral small vessel disease is associated with higher ratios of soluble‐epoxide hydrolase derived linoleic acid diols (12,13‐dihydroxyoctadecenoic acid [DiHOME] and 9,10‐DiHOME) to their parent epoxides (12(13)‐epoxyoctadecenoic acid [EpOME] 
Di Yu   +35 more
doaj   +1 more source

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