Results 91 to 100 of about 9,669 (153)

Sleep quality and cerebrospinal fluid oxysterols in degenerative dementias: correlations and possible biomedical implications

Redox Experimental Medicine
Objective: The combination and tentative correlation of a selected set of polysomnographic tests with the quantitative measurement of oxysterols of pathophysiological relevance in the cerebrospinal fluid (CSF) of patients with Alzheimer’s degenerative ...
Luca Pradotto, Stefania Cattaldo, Lorenzo Priano, Riccardo Cremascoli, Elisa Prina, Alessandra Milesi, Stefania Mai, Paolo Piterà, Domenico Tripodi, Giuseppe Poli, Valerio Leoni, Alessandro Mauro   +11 more
doaj   +1 more source

Identification of oxysterols in human bile and pigment gallstones

, 2001
Background & Aims: Although cholesterol is the most abundant sterol in animal tissues, oxidized products of cholesterol (oxysterols) also occur in mammalian organs and blood and are cytotoxic, atherogenic, and carcinogenic.
Haigh, WGeoffrey, Lee, SP
core   +1 more source

Oxysterols: chemical synthesis, biosynthesis and biological activities.

, 1986
As a class of compounds, oxysterols have demonstrated a wide variety of biological properties. Due to the general interest in these compounds, new methods of chemical synthesis have been developed to provide them for biological investigation.
Herbert H. Kohl, Venkata B. B. Nanduri, Frederick R. Taylor, Kohl, H H, Nanduri, V B, Taylor, F R, Edward J. Parish, Parish, E J   +7 more
core   +2 more sources

Effect of oxysterols on hematopoietic progenitor cells

, 2002
OBJECTIVES: Oxysterols are hydroxylated derivatives of cholesterol detected in blood, cells, and tissues. They exhibit a number of biologic activities, including inhibition of cellular proliferation and cytotoxicity associated with induction of apoptosis.
JB Hosking (14472156), CC Gregorio-King (14472153), Kristy Bolton (13077711), M Ferguson (9858185), Fiona Collier (17377171), GR Collier (14471649), MA Kirkland (14448294)   +6 more
core  

Oxysterols and related sterols. Chemical, biochemical and biological aspects

, 2015
Cholesterol and its congeners phytosterols – which are widely present in animals, plants and/or micro-organisms, are parent compounds of oxygenated forms namely oxysterols and oxyphytosterols that are produced either from auto-oxidation or ...
Lizard, Gérard, IULIANO, Luigi, Sá E. Melo, Maria Luisa, Cruz Silva, Maria Manuel   +3 more
core   +1 more source

Control of the immune system by oxysterols and cancer development

, 2012
Oxysterols/oxysterol receptors have been shown to modulate several immune cell subsets, such as macrophages, T-cells and B-cells, neutrophils and dendritic cells (DCs).
Russo V., Traversari C.
core   +1 more source

Implication of Oxysterols and Phytosterols in Aging and Human Diseases

Cholesterol is easily oxidized and can be transformed into numerous oxidation products, among which oxysterols. Phytosterols are plant sterols related to cholesterol.
Vigne, Solenne, Pot, Caroline
core   +1 more source

Studies on oxysterols : origins, properties and roles

, 2003
Oxysterols are derivatives of cholesterol present at low concentrations in a variety of physiological compartments. The major oxysterols in human circulation are formed from pools of cholesterol that may be distinguished by their miscibility with plasma ...
Steve Meaney (340357)
core   +1 more source

Current trends in oxysterols & related sterols.

, 2018
It is now widely accepted that oxysterols are more than metabolic intermediates but are actually bona fide lipid mediators. To qualify as a bona fide lipid mediator, a lipid compound should meet three conditions.
Muccioli, Giulio, Iuliano, Luigi, Lizard, Gérard, Muccioli, Giulio G.   +3 more
core   +1 more source

Oxysterols suppress constitutive fibrinogen expression

, 2003
SummaryElevated levels of both fibrinogen and cholesterol are risk factors in coronary artery disease. Previously we reported a metabolic link between fibrinogen and lipid metabolism in that HepG2 cells that were programmed by transfection of Bβ ...
Colvin Redman, Hui Xia
core   +1 more source