Microbial synthesis of the plant natural product precursor p-coumaric acid with Corynebacterium glutamicum [PDF]
Microbial Cell Factories, 2023 Background Phenylpropanoids such as p-coumaric acid represent important precursors for the synthesis of a broad range of plant secondary metabolites including stilbenoids, flavonoids, and lignans, which are of pharmacological interest due to their health-
Mario Mutz +4 more
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Global transcriptomic response of Escherichia coli to p-coumaric acid [PDF]
Microbial Cell Factories, 2022 The aromatic compound p-coumaric acid (p-CA) is a secondary metabolite produced by plants. This aromatic acid and derived compounds have positive effects on human health, so there is interest in producing them in biotechnological processes with ...
José Ignacio Rodríguez-Ochoa +6 more
doaj +4 more sources
p-Coumaric acid alleviates adriamycin-induced hepatotoxicity in rats
Asian Pacific Journal of Tropical Biomedicine, 2021 Objective: To evaluate the effect of p-coumaric acid against adriamycin-induced hepatotoxicity in rats. Methods: The rats were divided into 4 groups. The control group received solvent; the p-coumaric acid group was treated with 100 mg/kg of p-coumaric ...
Zeinab Rafiee +3 more
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Cinnamic acid and p-coumaric acid are metabolized to 4-hydroxybenzoic acid by Yarrowia lipolytica [PDF]
AMB Express, 2023 Yarrowia lipolytica has been explored as a potential production host for flavonoid synthesis due to its high tolerance to aromatic acids and ability to supply malonyl-CoA.
Oliver Konzock +4 more
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Low molecular weight ε-caprolactone-p-coumaric acid copolymers as potential biomaterials for skin regeneration applications. [PDF]
PLoS ONE, 2019 ε-caprolactone-p-coumaric acid copolymers at different mole ratios (ε-caprolactone:p-coumaric acid 1:0, 10:1, 8:1, 6:1, 4:1, and 2:1) were synthesized by melt-polycondensation and using 4-dodecylbenzene sulfonic acid as catalyst. Chemical analysis by NMR
Marco Contardi +13 more
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Influence of Polymers Diversity on the Dissolution Kinetics of Encapsulated p-Coumaric Acid in Oral Systems [PDF]
Gelsp-coumaric acid is a natural phenolic compound with antioxidant activity, but its poor solubility and low bioavailability limit its practical use in oral formulations. The aim of this study is to evaluate how different polymers affect the dissolution and
Monika Jokubaite +2 more
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Design, synthesis, characterization of ferulic acid and <i>p</i>-coumaric acid amide derivatives as an antibacterial/antioxidant agent. [PDF]
Pharm Sci Adv, 2023 Ferulic acid and p-coumaric acid, cinnamic derivatives of phenolic acid, have antibacterial, prooxidant, and antioxidant effects. In this study ferulic acid and p-coumaric acid amide derivatives were investigated for their antibacterial and antioxidant ...
Halpani CG, Mishra S.
europepmc +2 more sources
Antioxidants, 2019 Controlling unwanted hyperpigmentation is a major challenge in dermatology and cosmetology, and safe and efficacious antimelanogenic agents are deemed useful for this purpose.
Yong Chool Boo
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Cell Wall-bound p-Coumaric and Ferulic Acid Analysis
Bio-Protocol, 2016 Hydroxycinnamic acids, such as p-coumaric acid and ferulic acid, are a major class of compounds derived from the phenylpropanoid pathway. These compounds are widely conserved in plants and primarily accumulate in the secondary cell wall.
Nickolas Anderson
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Poly(p-coumaric acid) nanoparticles alleviate temporomandibular joint osteoarthritis by inhibiting chondrocyte ferroptosis. [PDF]
Bioact MaterOxidative stress and inflammation are key drivers of osteoarthritis (OA) pathogenesis and disease progression. Herein we report the synthesis of poly(p-coumaric) nanoparticles (PCA NPs) from p-courmaic acid (p-CA), a naturally occurring phytophenolic ...
Guo J +9 more
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