Results 111 to 120 of about 6,406 (145)

The uremic toxin p-cresyl sulfate induces proliferation and migration of clear cell renal cell carcinoma via microRNA-21/ HIF-1α axis signals. [PDF]

Sci Rep, 2019
Wu TK, Wei CW, Pan YR, Hsu RJ, Wu CY, Yu YL.   +5 more
europepmc   +1 more source

Translational Medicine in Pulmonary-Renal Crosstalk: Therapeutic Targeting of p-Cresyl Sulfate Triggered Nonspecific ROS and Chemoattractants in Dyspneic Patients with Uremic Lung Injury. [PDF]

J Clin Med, 2018
Chang JF, Liang SS, Thanasekaran P, Chang HW, Wen LL, Chen CH, Liou JC, Yeh JC, Liu SH, Dai HM, Lin WN.   +10 more
europepmc   +1 more source

Beta-Glucans Supplementation Associates with Reduction in P-Cresyl Sulfate Levels and Improved Endothelial Vascular Reactivity in Healthy Individuals. [PDF]

PLoS One, 2017
Cosola C, De Angelis M, Rocchetti MT, Montemurno E, Maranzano V, Dalfino G, Manno C, Zito A, Gesualdo M, Ciccone MM, Gobbetti M, Gesualdo L.   +11 more
europepmc   +1 more source

The Role of Diet and Gut Microbiome in CKD Progression and Therapy. [PDF]

J Clin Med
Lau WL, Li W, Sumida K, Kalantar-Zadeh K.   +3 more
europepmc   +1 more source

Toxic microbiome and progression of chronic kidney disease: insights from a longitudinal CKD-microbiome study. [PDF]

Gut
Szeto CC, Ng JKC.
europepmc   +1 more source

Metabolomic Cerebrospinal Fluid Biomarkers for the Diagnosis of Atypical Parkinsonian Syndromes. [PDF]

Int J Mol Sci
Ye L, Wegner F, Smandzich NJ, Rudtke O, Efe GD, Höllerhage M, Schneidereit IV, Greten S, Schuchardt S, Klietz M.   +9 more
europepmc   +1 more source

Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology [PDF]

Toxicology in Vitro, 2015
The uremic solutes p-cresyl sulfate (pCS) and p-cresyl glucuronide (pCG) accumulate in patients with chronic kidney disease (CKD), and might contribute to disease progression. Moreover, retention of these solutes may directly be related to renal tubular function.
Jack Wetzels, Rosalinde Masereeuw, Jan Van Den Brand   +2 more
exaly   +8 more sources

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Indoxyl sulfate, not p-cresyl sulfate, is associated with cognitive impairment in early-stage chronic kidney disease

NeuroToxicology, 2016
Patients with chronic kidney disease (CKD) more commonly experience cognitive impairment, but the etiologies are not clear. Uremic toxins such as p-cresyl sulfate (PCS) and indoxyl sulfate (IS) have been shown to increase the risks of cardiovascular diseases and mortality; however, no study has investigated the associations of PCS and IS with cognitive
Cheng-Sheng Chen, Hwang Shang-Jyh, Yi-Hsin Yang   +2 more
exaly   +3 more sources

The Accumulation of Gut Microbiome–derived Indoxyl Sulfate and P-Cresyl Sulfate in Patients With End-stage Renal Disease

Journal of Renal Nutrition, 2022
Indoxyl sulfate (IS) and p-cresyl sulfate (pCS) are two important gut microbiota-generated protein-bound uremic toxins. The present study aims to explore the alterations of serum IS and pCS concentrations, their production, and daily removal in end-stage renal disease (ESRD).A case-controlled study was conducted based on 11 patients with ESRD and 11 ...
Xuechun Lin, Wangqun Liang, Li Li, Qianqian Xiong, Shuiqing He, Jing Zhao, Xiaolei Guo, Siyun Xiang, Piwei Zhang, Hong Wang, Chenjiang Ying, Ying Yao, Xuezhi Zuo   +12 more
openaire   +2 more sources