Objective To guide rational clinical use of synbiotics in the treatment of chronic kidney disease and the design of large-scale randomized controlled trials,we systematically evaluate and meta-analysis the effect of synbiotics on patients with chronic ...
JIANG Zhi-hui, ZHONG Xian-yang, LI Jian
doaj
Rationale & Objective: Protein-bound uremic toxins, including indoxyl sulfate and p-cresyl sulfate, are poorly removed by conventional dialysis and contribute to cardiovascular, inflammatory, and neurological complications in end-stage kidney disease.
Gonzalo Ramírez-Guerrero +8 more
doaj +1 more source
Improving the In Vitro Removal of Indoxyl Sulfate and p-Cresyl Sulfate by Coating Diatomaceous Earth (DE) and Poly-vinyl-pyrrolidone-co-styrene (PVP-co-S) with Polydopamine. [PDF]
Cicco SR +9 more
europepmc +1 more source
Effects of Microbiota-Driven Therapy on Circulating Indoxyl Sulfate and P-Cresyl Sulfate in Patients with Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]
Chen L, Shi J, Ma X, Shi D, Qu H.
europepmc +1 more source
Translational Medicine in Uremic Vascular Calcification: Scavenging ROS Attenuates p-Cresyl Sulfate-Activated Caspase-1, NLRP3 Inflammasome and Eicosanoid Inflammation in Human Arterial Smooth Muscle Cells. [PDF]
Chang JF +11 more
europepmc +1 more source
Associations Between Uraemic Toxins and Gut Microbiota in Adults Initiating Peritoneal Dialysis
Declining kidney function contributes to the accumulation of uraemic toxins produced by gut microbiota, leading to the uraemic syndrome. This study aimed to identify associations between uraemic toxins, diet quality, symptoms and the gut microbiota in ...
Philippa James +11 more
doaj +1 more source
-Derived p-Cresyl Metabolites Induce Inflammation and Apoptosis in Biliary Epithelial Cells
Objective Primary biliary cholangitis (PBC) is an autoimmune cholestatic liver disease, and the effects of p-cresyl sulfate (PCS) and p-cresyl glucuronide (PCG) in PBC remain unclear.
Haiyan Yu +7 more
doaj +1 more source
p-Cresyl sulfate predicts clinical outcomes in sustained peritoneal dialysis: a 5-year follow-up cohort study and meta-analysis. [PDF]
Chen Z +6 more
europepmc +1 more source
Circulating p-Cresyl Sulfate, Non-Hepatic Alkaline Phosphatase and Risk of Bone Fracture Events in Chronic Kidney Disease-Mineral Bone Disease. [PDF]
Chang JF +8 more
europepmc +1 more source

