Results 71 to 80 of about 9,946 (182)

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou   +7 more
wiley   +1 more source

Investigation of Metabolites in Feces and Plasma Associated with the Number of Piglets Weaned per Sow per Year

open access: yesMetabolites
Background: Sow reproductive performance is a critical parameter for the productivity of commercial pig farms. Gut microbiota is associated with performance in sow reproduction.
Takamitsu Tsukahara   +7 more
doaj   +1 more source

Prenatal morphine exposure reduces pyramidal neurons in CA1, CA2 and CA3 subfields of mice hippocampus [PDF]

open access: yes, 2014
Objective(s): This study was carried out to evaluate the effect of maternal morphine exposure during gestational and lactation period on pyramidal neurons of hippocampus in 18 and 32 day mice offspring.
Ghafari, S., Golalipour, M.J.
core   +1 more source

Chronic Kidney Disease Increases Cerebral Microbleeds in Mouse and Man. [PDF]

open access: yes, 2020
Brain microbleeds are increased in chronic kidney disease (CKD) and their presence increases risk of cognitive decline and stroke. We examined the interaction between CKD and brain microhemorrhages (the neuropathological substrate of microbleeds) in ...
Bangash, Maria   +13 more
core  

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

open access: yesAutism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni   +6 more
wiley   +1 more source

Distal Colon Motor Dysfunction in Mice with Chronic Kidney Disease: Putative Role of Uremic Toxins

open access: yesToxins, 2018
Although gastrointestinal complications are a common feature of patients with chronic kidney disease (CKD), the impact of uremia on bowel motility remains poorly understood.
Elsa Hoibian   +4 more
doaj   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

open access: yesFood Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao   +8 more
wiley   +1 more source

Dietary Fibre Intake Is Associated with Serum Levels of Uraemic Toxins in Children with Chronic Kidney Disease

open access: yesToxins, 2021
Imbalanced colonic microbial metabolism plays a pivotal role in generating protein-bound uraemic toxins (PBUTs), which accumulate with deteriorating kidney function and contribute to the uraemic burden of children with chronic kidney disease (CKD ...
Amina El Amouri   +11 more
doaj   +1 more source

Chronic kidney disease and fibrosis : the role of uremic retention solutes [PDF]

open access: yes, 2015
Chronic kidney disease (CKD) is a major global health concern, and the uremic state is highly associated with fibrogenesis in several organs and tissues.
Glorieux, Griet   +4 more
core   +3 more sources

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda   +5 more
wiley   +1 more source

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