Results 51 to 60 of about 9,946 (182)
Serum P-Cresyl Sulfate Is a Predictor of Central Arterial Stiffness in Patients on Maintenance Hemodialysis. [PDF]
Toxins (Basel), 2019 Arterial stiffness (AS) has an important impact on the outcomes of patients on hemodialysis (HD), and p-cresyl sulfate (PC) can mediate the process of vascular damage. We aimed to investigate the relationship between carotid–femoral pulse wave velocity (cfPWV) and the level of PCs in HD patients.
Lai YH +5 more
europepmc +4 more sources
Biomedicines, 2023 Studies have demonstrated that a low-protein diet supplemented with ketoanalogs (KAs) could significantly retard progression of renal function in patients with chronic kidney disease (CKD) stages 3–5.
George Chang +4 more
doaj +1 more source
Bisphenol A in chronic kidney disease [PDF]
, 2013 Phenols are uremic toxins of intestinal origin formed by bacteria during protein metabolism. Of these molecules, p-cresol is the most studied and has been associated with renal function impairment and vascular damage. Bisphenol A (BPA) is a molecule with
Bosch, Ricardo J. +5 more
core +4 more sources
Toxins, 2014 Chronic kidney disease (CKD) has been considered a major risk factor for cardiovascular diseases. Although great advances have recently been made in the pathophysiology and treatment of cardiovascular diseases, CKD remains a major global health problem ...
Shunsuke Ito, Masayuki Yoshida
doaj +1 more source
Uraemic toxins and new methods to control their accumulation : game changers for the concept of dialysis adequacy [PDF]
, 2015 The current concept of an adequate dialysis based only on the dialysis process itself is rather limited. We now have considerable knowledge of uraemic toxicity and improved tools for limiting uraemic toxin accumulation. It is time to make use of these. A
Glorieux, Griet, Tattersall, James
core +2 more sources
Protein-Bound Uremic Toxins: New Insight from Clinical Studies
Toxins, 2011 The uremic syndrome is attributed to the progressive retention of a large number of compounds which, under normal conditions, are excreted by healthy kidneys. The compounds are called uremic toxins when they interact negatively with biological functions.
Ziad A. Massy +2 more
doaj +1 more source
Uremic Toxins and Protein-Bound Therapeutics in AKI and CKD: Up-to-Date Evidence
Toxins, 2021 Uremic toxins are defined as harmful metabolites that accumulate in the human body of patients whose renal function declines, especially chronic kidney disease (CKD) patients. Growing evidence demonstrates the deteriorating effect of uremic toxins on CKD
Jia-Huang Chen, Chih-Kang Chiang
doaj +1 more source
Archives of Medical Science, 2013 Previous studies have shown that serum p-cresyl sulfate (PCS) and indoxyl sulfate (IS) were significantly related to clinical outcomes in patients on hemodialysis (HD). However, evidence for the relationship in elderly HD patients remains scarce. We explore whether the two toxins can predict clinical outcomes in elderly HD patients.Fifty stable HD ...
Lin, Cheng-Jui +7 more
openaire +2 more sources
The Medium Cut-Off Membrane Does Not Lower Protein-Bound Uremic Toxins
Toxins, 2022 The accumulation of protein-bound uremic toxins (PBUT) is associated with increased cardiovascular outcomes in patients on dialysis. However, the efficacy of PBUT removal for a medium-cutoff (MCO) membrane has not been clarified.
Yang Gyun Kim +8 more
doaj +1 more source
Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function. [PDF]
, 2018 We developed an innovative biomaterial-based approach to repair the critical neural circuitry that controls diaphragm activation by locally delivering brain-derived neurotrophic factor (BDNF) to injured cervical spinal cord.
Ghosh, Biswarup +8 more
core +2 more sources