Correlation between Saliva Levels and Serum Levels of Free Uremic Toxins in Healthy Volunteers
Toxins, 2023 The objective of the present study was to investigate the putative correlation between the saliva concentration and free serum concentration for 10 uremic toxins (UTs; eight protein-bound solutes: 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF),
Nicolas Fabresse +6 more
doaj +1 more source
Effects of Sevelamer Hydrochloride on Uremic Toxins Serum Indoxyl Sulfate and P-Cresyl Sulfate in Hemodialysis Patients. [PDF]
J Clin Med Res, 2017 Beside the phosphate binding effect, non-calcium non-aluminum phosphate binder, namely sevelamer hydrochloride (SH), has many other effects in dialysis patients. It can absorb many other compounds, decrease low-density lipoprotein cholesterol (LDL-C) level, and attenuate the progression of vascular calcification; it has been reported to have anti ...
Lin CJ +6 more
europepmc +4 more sources
Removal of Protein-Bound Uremic Toxins Using Binding Competitors in Hemodialysis: A Narrative Review
Toxins, 2021 Removal of protein-bound uremic toxins (PBUTs) during conventional dialysis is insufficient. PBUTs are associated with comorbidities and mortality in dialysis patients.
Vaibhav Maheshwari +3 more
doaj +1 more source
Serum P-Cresyl Sulfate Is a Predictor of Central Arterial Stiffness in Patients on Maintenance Hemodialysis. [PDF]
Toxins (Basel), 2019 Arterial stiffness (AS) has an important impact on the outcomes of patients on hemodialysis (HD), and p-cresyl sulfate (PC) can mediate the process of vascular damage. We aimed to investigate the relationship between carotid–femoral pulse wave velocity (cfPWV) and the level of PCs in HD patients.
Lai YH +5 more
europepmc +4 more sources
p ‐Cresyl Sulfate Aggravates Cardiac Dysfunction Associated With Chronic Kidney Disease by Enhancing Apoptosis of Cardiomyocytes [PDF]
Journal of the American Heart Association, 2015 Hui Han, Zhu Jinzhou, Zhengbin Zhu
exaly +2 more sources
MO277: Effect of P-Cresyl Sulfate in Cardiorenal Axis in Mice
Nephrology Dialysis Transplantation, 2022 Abstract BACKGROUND AND AIMS Uremic toxins (UT) are extremely relevant for the understanding of pathologies of the cardiovascular system once kidney and heart have a close relationship and share different functions.
Carlos Alexandre Falconi +5 more
openaire +1 more source
Basolateral transport of the uraemic toxin p-cresyl sulfate: role for organic anion transporters? [PDF]
Nephrology Dialysis Transplantation, 2011 Contains fulltext : 96670.pdf (Publisher’s version ) (Open Access)
Mutsaers, R. +9 more
openaire +5 more sources
P-cresyl sulfate is a valuable predictor of clinical outcomes in pre-ESRD patients. [PDF]
Biomed Res Int, 2014 Background/Aims. Previous studies have reported p-cresyl sulfate (PCS) was related to endothelial dysfunction and adverse clinical effect. We investigate the adverse effects of PCS on clinical outcomes in a chronic kidney disease (CKD) cohort study.Methods. 72 predialysis patients were enrolled from a single medical center.
Lin CJ +7 more
europepmc +3 more sources
Biomolecules, 2023 Diabetic kidney disease (DKD) is one of the most debilitating complications of type 2 diabetes mellitus (T2DM), as it progresses silently to end-stage renal disease (ESRD). The discovery of novel biomarkers of early DKD becomes acute, as its incidence is
Lavinia Balint +13 more
doaj +1 more source
Gut-Microbiota-Metabolite Axis in Early Renal Function Decline.
PLoS ONE, 2015 IntroductionSeveral circulating metabolites derived from bacterial protein fermentation have been found to be inversely associated with renal function but the timing and disease severity is unclear.
Clara Barrios +10 more
doaj +1 more source