Results 41 to 50 of about 6,406 (145)
Future Foods, 2021 Fructooligosaccharide (FOS) is one of the most important and well-known prebiotics that confers health benefits on the host. The effect of FOS is frequently associated with modulation of the abundance of gut microbes.
Jingbo Lu +6 more
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Toxins, 2020 Protein-bound uremic toxins (PBUTs) are predominantly excreted by renal tubular secretion and hardly removed by traditional hemodialysis (HD). Accumulation of PBUTs is proposed to contribute to the increased morbidity and mortality of patients with end ...
Maaike K. van Gelder +11 more
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Medicina, 2023 Introduction: Numerous studies to date have shown that the development of dysbiotic gut microbiota is a characteristic finding in chronic kidney disease (CKD).
Teodor Kuskunov +5 more
doaj +1 more source
Atorvastatin attenuates p‑cresyl sulfate‑induced atherogenesis and plaque instability in ApoE knockout mice. [PDF]
Mol Med Rep, 2016 p-cresyl sulfate (PCS) is a protein-bound uremic toxin retained in the blood of patients with chronic kidney disease (CKD) As atherosclerosis is a primary cardiovascular complication for patients with CKD, the aim of the present study was to investigate the mechanisms underlying the aggravation of atherosclerosis by PCS.
Han H +5 more
europepmc +4 more sources
Biomedicines, 2023 Studies have demonstrated that a low-protein diet supplemented with ketoanalogs (KAs) could significantly retard progression of renal function in patients with chronic kidney disease (CKD) stages 3–5.
George Chang +4 more
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Toxins, 2014 Chronic kidney disease (CKD) has been considered a major risk factor for cardiovascular diseases. Although great advances have recently been made in the pathophysiology and treatment of cardiovascular diseases, CKD remains a major global health problem ...
Shunsuke Ito, Masayuki Yoshida
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Protein-Bound Uremic Toxins: New Insight from Clinical Studies
Toxins, 2011 The uremic syndrome is attributed to the progressive retention of a large number of compounds which, under normal conditions, are excreted by healthy kidneys. The compounds are called uremic toxins when they interact negatively with biological functions.
Ziad A. Massy +2 more
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Uremic Toxins and Protein-Bound Therapeutics in AKI and CKD: Up-to-Date Evidence
Toxins, 2021 Uremic toxins are defined as harmful metabolites that accumulate in the human body of patients whose renal function declines, especially chronic kidney disease (CKD) patients. Growing evidence demonstrates the deteriorating effect of uremic toxins on CKD
Jia-Huang Chen, Chih-Kang Chiang
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The Medium Cut-Off Membrane Does Not Lower Protein-Bound Uremic Toxins
Toxins, 2022 The accumulation of protein-bound uremic toxins (PBUT) is associated with increased cardiovascular outcomes in patients on dialysis. However, the efficacy of PBUT removal for a medium-cutoff (MCO) membrane has not been clarified.
Yang Gyun Kim +8 more
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Toxins, 2020 High serum levels of microbiota-derived uremic toxins, indoxyl sulfate (IS) and p-cresyl sulfate (PCS), are associated with chronic kidney disease (CKD) progression and cardiovascular complications.
Maria Teresa Rocchetti +10 more
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