Results 41 to 50 of about 25,586,764 (161)

Correlation between Saliva Levels and Serum Levels of Free Uremic Toxins in Healthy Volunteers

Toxins, 2023
The objective of the present study was to investigate the putative correlation between the saliva concentration and free serum concentration for 10 uremic toxins (UTs; eight protein-bound solutes: 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF),
Nicolas Fabresse, Islam Amine Larabi, Emuri Abe, Elodie Lamy, Claire Rigothier, Ziad A. Massy, Jean-Claude Alvarez   +6 more
doaj   +1 more source

Removal of Protein-Bound Uremic Toxins Using Binding Competitors in Hemodialysis: A Narrative Review

Toxins, 2021
Removal of protein-bound uremic toxins (PBUTs) during conventional dialysis is insufficient. PBUTs are associated with comorbidities and mortality in dialysis patients.
Vaibhav Maheshwari, Xia Tao, Stephan Thijssen, Peter Kotanko   +3 more
doaj   +1 more source

MO277: Effect of P-Cresyl Sulfate in Cardiorenal Axis in Mice

Nephrology Dialysis Transplantation, 2022
Abstract BACKGROUND AND AIMS Uremic toxins (UT) are extremely relevant for the understanding of pathologies of the cardiovascular system once kidney and heart have a close relationship and share different functions.
Carlos Alexandre Falconi, Carolina Victoria Cruz Junho, Fernanda Fogaça-Ruiz, Raquel Silva Neres Dos Santos, Andréa E M Stinghen, Marcela Carneiro-Ramos   +5 more
openaire   +1 more source

P‐Cresyl Sulfate Aggravates Cardiac Dysfunction Associated With Chronic Kidney Disease by Enhancing Apoptosis of Cardiomyocytes [PDF]

Journal of the American Heart Association, 2015
Hui Han, Zhu Jinzhou, Zhengbin Zhu
exaly   +2 more sources

Basolateral transport of the uraemic toxin p-cresyl sulfate: role for organic anion transporters? [PDF]

Nephrology Dialysis Transplantation, 2011
Contains fulltext : 96670.pdf (Publisher’s version ) (Open Access)
Mutsaers, R., Mutsaers, R., Mutsaers, R., Wilmer, M.J.G., Wilmer, M.J.G., Wilmer, M.J.G., van den Heuvel, L.P.W.J., van den Heuvel, L.P.W.J., Hoenderop, J.G.J., Masereeuw, R.   +9 more
openaire   +5 more sources

Quantitative, Targeted Analysis of Gut Microbiota Derived Metabolites Provides Novel Biomarkers of Early Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients

Biomolecules, 2023
Diabetic kidney disease (DKD) is one of the most debilitating complications of type 2 diabetes mellitus (T2DM), as it progresses silently to end-stage renal disease (ESRD). The discovery of novel biomarkers of early DKD becomes acute, as its incidence is
Lavinia Balint, Carmen Socaciu, Andreea Iulia Socaciu, Adrian Vlad, Florica Gadalean, Flaviu Bob, Oana Milas, Octavian Marius Cretu, Anca Suteanu-Simulescu, Mihaela Glavan, Silvia Ienciu, Maria Mogos, Dragos Catalin Jianu, Ligia Petrica   +13 more
doaj   +1 more source

P-cresyl sulfate is a valuable predictor of clinical outcomes in pre-ESRD patients. [PDF]

Biomed Res Int, 2014
Background/Aims. Previous studies have reported p-cresyl sulfate (PCS) was related to endothelial dysfunction and adverse clinical effect. We investigate the adverse effects of PCS on clinical outcomes in a chronic kidney disease (CKD) cohort study.Methods. 72 predialysis patients were enrolled from a single medical center.
Lin CJ, Pan CF, Chuang CK, Sun FJ, Wang DJ, Chen HH, Liu HL, Wu CJ.   +7 more
europepmc   +3 more sources

Protein-Bound Uremic Toxins in Hemodialysis Patients Relate to Residual Kidney Function, Are Not Influenced by Convective Transport, and Do Not Relate to Outcome

Toxins, 2020
Protein-bound uremic toxins (PBUTs) are predominantly excreted by renal tubular secretion and hardly removed by traditional hemodialysis (HD). Accumulation of PBUTs is proposed to contribute to the increased morbidity and mortality of patients with end ...
Maaike K. van Gelder, Igor R. Middel, Robin W. M. Vernooij, Michiel L. Bots, Marianne C. Verhaar, Rosalinde Masereeuw, Muriel P. Grooteman, Menso J. Nubé, M. A. van den Dorpel, Peter J. Blankestijn, Maarten B. Rookmaaker, Karin G.F. Gerritsen   +11 more
doaj   +1 more source

Fructooligosaccharide decreases the production of uremic toxin precursor through modulating gut microbes mediated tyrosine metabolism pathway

Future Foods, 2021
Fructooligosaccharide (FOS) is one of the most important and well-known prebiotics that confers health benefits on the host. The effect of FOS is frequently associated with modulation of the abundance of gut microbes.
Jingbo Lu, Jianping Li, Jiating Yin, Chengxi Li, Sen Zhang, Jianming Guo, Jinao Duan   +6 more
doaj   +1 more source

The Effect of Synbiotic Supplementation on Uremic Toxins, Oxidative Stress, and Inflammation in Hemodialysis Patients—Results of an Uncontrolled Prospective Single-Arm Study

Medicina, 2023
Introduction: Numerous studies to date have shown that the development of dysbiotic gut microbiota is a characteristic finding in chronic kidney disease (CKD).
Teodor Kuskunov, Eduard Tilkiyan, Daniel Doykov, Krasimir Boyanov, Anelia Bivolarska, Bozhidar Hristov   +5 more
doaj   +1 more source