Results 81 to 90 of about 25,586,764 (161)
Toxins, 2021 Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting in uremia. Uremic toxins are classified into three categories: free
Yong Jin Lim +4 more
doaj +1 more source
SusMat, Volume 6, Issue 5, October 2026.This graphical ToC illustrates a tubular‐inspired detoxifier (SDCMs–DS) that halts acute kidney injury progression. Inspired by proximal tubular epithelial cells (PTECs), the biomimetic design combines dissociation‐adsorption clearance of protein‐bound uremic toxins (PBUTs) with antioxidant protection. During hemoperfusion, danshensu (DS) released from
Yilin Wang +12 more
wiley +1 more source
Serum levels of microbial metabolites during treatment with arabinoxylan oligosaccharides (AXOS).
, 2016 Evolution of serum urea (A), p-cresyl sulfate (B), p-cresyl glucuronide (C), indoxyl sulfate (D), trimethylamine N-oxide (E) and phenylacetylglutamine (F) during treatment with AXOS.
Kristin Verbeke (109066) +8 more
core +1 more source
Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease
VIEW, Volume 7, Issue 5, October 2026.This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin +5 more
wiley +1 more source
Toxins, 2017 Elevated circulating uremic toxins are associated with a variety of symptoms and organ dysfunction observed in patients with chronic kidney disease (CKD). Indoxyl sulfate (IS) and p-cresyl sulfate (PCS) are representative uremic toxins that exert various
Emiko Sato +17 more
doaj +1 more source
Hemodialysis International, Volume 30, Issue 4, Page 689-697, October 2026.ABSTRACT Introduction Tenapanor, a minimally absorbed intestinal NHE3 inhibitor approved for hyperphosphatemia in dialysis, lowers phosphate and reduces intestinal sodium absorption. Its sodium–water signal may have implications beyond phosphate but remains poorly separated from diarrhea‐mediated losses and dialysis prescription artifacts. Methods This
Lucas Maciel de Almeida Corrêa +8 more
wiley +1 more source
International Wound Journal, Volume 23, Issue 10, October 2026.ABSTRACT Haemodialysis patients face a markedly elevated risk of foot lesions because of coexisting diabetes mellitus (DM), peripheral arterial disease (PAD) and uremia‐related impairment of wound healing. Structured outpatient strategies and the optimal place of basic fibroblast growth factor (bFGF) within a stepwise algorithm remain poorly defined ...
Sadanori Akita +4 more
wiley +1 more source
Current Research in Microbial SciencesBackground: Patients with end-stage kidney disease (ESKD) accumulate toxic metabolites that contribute to severe clinical complications. Peritoneal dialysis (PD) and hemodialysis (HD) exhibit distinct capacites for toxin clearance.
Min Lu +12 more
doaj +1 more source
The FASEB Journal, Volume 40, Issue 18, 30 September 2026.Bidirectional communication between oocytes and granulosa cells undergoes progressive remodeling during bovine folliculogenesis. Integrative transcriptomic analysis identified stage‐specific ligand‐receptor signaling networks coordinating structural, metabolic, and developmental processes.
Noemi Monferini +6 more
wiley +1 more source
FEBS Open Bio, Volume 16, Issue 9, Page 1645-1656, September 2026.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source