Results 41 to 50 of about 243,388 (247)
Does the environmental Phillips curve hypothesis hold within the Ghanaian context?
Scientific AfricanThis study examines the relationship between environmental quality and unemployment in Ghana using annual data spanning the period from 1990 to 2019. It also assesses the impact of gender-segregated unemployment rate on environmental quality.
Richmond Addison +2 more
doaj +1 more source
Design, synthesis, and biological evaluation of 6-methoxy-2-arylquinolines as potential P-glycoprotein inhibitors [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): In the present study,a new series of 6-methoxy-2-arylquinoline analogues was designed and synthesized as P-glycoprotein (P-gp) inhibitors using quinine and flavones as the lead compounds. Materials and Methods: The cytotoxic activity of the
Sayyed Mohammad Abutorabzadeh +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Effects of astragaloside IV on the pharmacokinetics of omeprazole in rats
Pharmaceutical Biology, 2019 Context: Omeprazole and astragaloside IV (AS-IV) are widely used for the treatment of gastric ulcers in China clinics. Objective: This study investigates the effects of AS-IV on the pharmacokinetics of omeprazole in rats.
Wei Liu, Guozhi Liu, Jing Liu
doaj +1 more source
Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism
Pharmaceutical Biology, 2020 Context Both nobiletin (NBL) and glycyrrhizin (GL) have anti-inflammatory and antitumor properties. These agents may be co-administered in the clinic. However, the drug–drug interaction between them is not clear.
Hao Wang +6 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Ingeniería Mecánica, 2008 El presente trabajo está dedicado a la optimización bajo criterios múltiples de la planificación de procesos de ensamblemecánico a partir de su modelo geométrico tridimensional.
L. L. Tomás García +1 more
doaj
The effects of triptolide on the pharmacokinetics of sorafenib in rats and its potential mechanism
Pharmaceutical Biology, 2017 Context: Combining sorafenib with triptolide could inhibit tumour growth with greater efficacy than single-agent treatment. However, their herb–drug interaction remains unknown.
Xianming Wang +4 more
doaj +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source