Results 31 to 40 of about 113,808 (269)

JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand. [PDF]

, 2009
Background: cJun terminal kinase (JNK) is constitutively activated in most hepatocellular carcinomas (HCCs), yet its exact role in carcinogenesis remains controversial.
Bruns, Christiane, Camaj, Peter, De Toni, Enrico, Eichhorst, Sören T., Gallmeier, Eike, Gerbes, Alexander L., Göke, Burkhard, Kolligs, Frank T., Mucha, Simon R., Rizzani, Antonia, Thasler, Wolfgang E.   +10 more
core   +1 more source

Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons

BMC Neuroscience, 2005
Background The transcription factor AP-1 positively controls synaptic plasticity at the Drosophila neuromuscular junction. Although in motor neurons, JNK has been shown to activate AP-1, a positive regulator of growth and strength at the larval NMJ, the ...
Bohmann Dirk, Patel Chirag, Navratilova Zaneta, Narayanan Radhakrishnan, Etter Paul D, Jasper Heinrich, Ramaswami Mani   +6 more
doaj   +1 more source

Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways [PDF]

, 2007
Migration and proliferation of smooth muscle cells are key to a number of physiological and pathological processes, including wound healing and the narrowing of the vessel wall.Previous work has shown links between inflammatory stimuli and vascular ...
Agnes Czibula, Andrea R. King, Anthony G. Wilson, Bonventre, Che, Choukroun, David C. Crossman, Du, Emily Heath, Endre Kiss-Toth, Force, Goldschmidt, Grosshans, Hegedus, Hegedus, Hongtao Guan, Hye Youn Sung, Iynedjian, Jones, Ju, Katalin Eder, King, Kiss-Toth, Kiss-Toth, Kiss-Toth, Koo, Lai, Levchenko, Li, Majesky, Mata, McCarthy, Michnick, Mii, Morton, Ohoka, Remy, Remy, Robinson, S. Kim Suvarna, Saka, Sato, Satterthwaite, Schwarzer, Seher, Sheila E. Francis, Stary, Stary, Stary, Steven K. Dower, Surapisitchat, Takeishi, Touyz, Warner, Wilkin, Xia, Yamakawa, Yang, Yue   +58 more
core   +1 more source

Effect of Doxofylline on Reducing the Inflammatory Response in Mechanically Ventilated Rats with Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2021
Chu-Yun Liu,1 Jian-Hua Wu,1 Zhi-Yuan Chen,1 Yi Zhang,1 Chun-Ling Huang,2 Ai-Mei Lin,1 Xiao-Ting Xu,1 Xiao-Hua Gao1 1Department of Anesthesiology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, People’s Republic of China ...
Liu CY, Wu JH, Chen ZY, Zhang Y, Huang CL, Lin AM, Xu XT, Gao XH   +7 more
doaj  

Multifractional Poisson process, multistable subordinator and related limit theorems [PDF]

, 2014
We introduce a multistable subordinator, which generalizes the stable subordinator to the case of time-varying stability index. This enables us to define a multifractional Poisson process.
Molchanov, Ilya, Ralchenko, Kostiantyn
core   +2 more sources

The Mechanism of Penehyclidine Hydrochloride and Its Effect on the Inflammatory Response of Lung Tissue in Rats with Chronic Obstructive Pulmonary Disease During Mechanical Ventilation [Retraction]

International Journal of COPD, 2023
Chen Z, Zhang Y, Wu J, et al. Int J Chron Obstruct Pulmon Dis. 2021;16:877–885. The Editor and Publisher of International Journal of Chronic Obstructive Pulmonary Disease are retracting the published article.
Chen Z, Zhang Y, Wu J, Gao X, Huang C, Lin Y, Xu X, Li Y   +7 more
doaj  

JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain

Journal of Neuroinflammation, 2012
Background White matter injury is the major form of brain damage in very preterm infants. Selective white matter injury in the immature brain can be induced by lipopolysaccharide (LPS)-sensitized hypoxic-ischemia (HI) in the postpartum (P) day 2 rat pups
Wang Lan-Wan, Tu Yi-Fang, Huang Chao-Ching, Ho Chien-Jung   +3 more
doaj   +1 more source

Propofol reduces anoxia-reoxygenation-induced injury of cardiomyocytes [PDF]

Jichu yixue yu linchuang, 2022
Objective To investigate the effect of propofol (Pro) on cardiomyocyte damage induced by anoxia-reoxygenation through regulating JNK/p38 MAPK pathway. Methods Divided the cells into control group, anoxia-reoxygenation (A/R) group, anoxia-reoxygenation ...
CHEN Si, YANG Fu-guo, PENG Hong-jun, CAO Wei-le, WANG Zhen-yu
doaj   +1 more source

Autophagy processes are dependent on EGF receptor signaling [PDF]

, 2018
Autophagy is a not well-understood conserved mechanism activated during nutritional deprivation in order to maintain cellular homeostasis. In the present study, we investigated the correlations between autophagy, apoptosis and the MAPK pathways in ...
Capodifoglio, Sabrina, Caruso, Marika, Conti, Pio, Flati, Vincenzo, Iuliis, Vincenzo De, Lanuti, Paola, Marino, Antonio, Marricareda, Valeria, Martinotti, Stefano, Marynuk, Anna, Talora, Claudio, Toniato, Elena, Ursi, Sebastiano   +12 more
core   +1 more source

c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells

Journal of Translational Medicine, 2011
Background Autophagy is a dynamic catabolic process characterized by the formation of double membrane vacuoles termed autophagosomes. LC3, a homologue of yeast Atg8, takes part in autophagosome formation, but the exact regulation mechanism of LC3 still ...
Guan Zhong, Ma JianGuo, Xia LiangPing, Wang LinLin, Li DanDan, Sun Ting, Feng GongKan, Zhu XiaoFeng   +7 more
doaj   +1 more source