Results 11 to 20 of about 25,432,439 (260)
CAB39 Promotes the Proliferation of Nasopharyngeal Carcinoma CNE-1 Cells via Up-Regulating p-JNK
Cancer Management and Research, 2020 Lifen Peng,1 Hailan Yan,2 Shuyi Qi,3 Lifei Deng4 1Department of Otolaryngology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, People’s Republic of China; 2Department of Clinical Medicine, Xi’an ...
Peng L, Yan H, Qi S, Deng L
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Yonsei Medical Journal, 2004 To evaluate the roles of 4 putative downstream molecules (ERK, p38 MAPK, JNK and AKT) of the RET signal pathway in the tumorigenesis of papillary carcinomas, the expression patterns of RET and phosphorylated forms of ERK, p38 MAPK, JNK and AKT were evaluated in 115 cases of papillary thyroid carcinomas by 3 mm-core tissue microarray based ...
Eunah, Shin +3 more
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XBP1s promotes the development of lung adenocarcinoma via the p‑JNK MAPK pathway
International Journal of Molecular Medicine, 2022 Spliced X‑box binding protein 1 (XBP1s) has been reported to participate in the pathogenesis of numerous types of cancer; however, whether XBP1s plays a role in lung cancer remains to be elucidated. In the present study, bioinformatics analysis was performed to determine the mRNA expression level of XBP1 in lung cancer and adjacent normal tissues. Gene
Jiang, Hongxia +5 more
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Induction of Melanogenesis by Fosfomycin in B16F10 Cells Through the Upregulation of P-JNK and P-p38 Signaling Pathways [PDF]
Antibiotics, 2020 Fosfomycin disodium salt (FDS), which is a water-soluble extract, is a bactericidal drug used to inhibit the synthesis of cells. Moreover, it has been found to be effective in the treatment of urinary tract infections. The present study was conducted to investigate the melanogenesis-stimulating effect of FDS in B16F10 cells.
Ullah, Sana +2 more
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p-JNK directly interacted with HATs and altered H3K9ac acetylation in primary mouse cardiomyocytes.
, 2021 (A and B) Co-immunoprecipitation (CoIP) of cell lysates from mouse myocardial cells exposed to six different experimental conditions with anti-p-JNK-protein G magnetic beads and immunoblot (IB) with an anti-P300-HAT, anti-PCAF-HAT, anti-H3K9ac, or anti-p-
Huanting Zhang (11846609) +6 more
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Cell Death & Disease, 2022 AbstractCervical cancer (CC) is the most frequently diagnosed genital tract cancer in females worldwide. Rac GTPase-activating protein 1 (RacGAP1) is one of the specific GTPase-activating proteins. As a novel tumor protooncogene, overexpression of RacGAP1 was related to the occurrence of various tumors, but its function in CC is still unclear.
Tianli Zhang +6 more
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JNK signalling in cancer: In need of new, smarter therapeutic targets [PDF]
, 2014 Copyright © 2013 The British Pharmacological Society. This is the accepted version of the following article: Bubici, C. and Papa, S. (2014), JNK signalling in cancer: in need of new, smarter therapeutic targets.
Concetta Bubici +3 more
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Spinal sample showing p-JNK and P38 associated with the pain signaling transduction of glial cell in neuropathic pain [PDF]
Spinal Cord, 2014 To investigate the signaling pathways after astrocytes were activated in neuropathic pain.Thirty-six Sprague Dawley (s.d.) rats were randomly divided into two groups (each group with 18 s.d. rats) including chronic constriction injury (CCI) of the sciatic nerve model group and sham operation group. Operation was perform ed on the right leg in all rats.
J, Cao, J-s, Wang, X-h, Ren, W-d, Zang
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Ecotoxicology and Environmental Safety, 2021 Cadmium is an environmental metal pollutant that has been a focus of research in recent years, which is reported to cause bone disease; however, its skeletal toxicity and the mechanism involved are not yet fully known. Therefore, this study used MC3T3-E1 subclone 14 cells to determine the mechanism of cadmium toxicity on bone.
Ling Ou +8 more
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Diosmetin Ameliorates Vascular Dysfunction and Remodeling by Modulation of Nrf2/HO-1 and p-JNK/p-NF-κB Expression in Hypertensive Rats [PDF]
Antioxidants, 2021 Diosmetin is a citrus flavonoid that has antioxidant and anti-inflammatory effects. This study examined the effect of diosmetin on blood pressure and vascular alterations and its underlying mechanisms in experimentally hypertensive rats. Male Sprague rats were administered Nω-nitro-l-arginine methyl ester L-NAME for five weeks and were given diosmetin ...
Sariya Meephat +5 more
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