Results 51 to 60 of about 3,904,130 (286)

International Multicenter Evaluation of Autoantibodies to Ribosomal P Proteins [PDF]

Clinical and Vaccine Immunology, 2006
ABSTRACT Autoantibodies to the ribosomal phosphoproteins (Rib-P) are a serological feature of patients with systemic lupus erythematosus (SLE). The reported prevalence of anti-Rib-P antibodies in SLE ranges from 10 to 40%, being higher in Asian patients.
Michael, Mahler, Kai, Kessenbrock, Magdalena, Szmyrka, Yoshinari, Takasaki, Ignacio, Garcia-De La Torre, Yehuda, Shoenfeld, Falk, Hiepe, Chen, Shun-le, Carlos A, von Mühlen, Henning, Locht, Peter, Höpfl, Allan, Wiik, Westley, Reeves, Marvin J, Fritzler   +13 more
openaire   +6 more sources

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Isolated gestational proteinuria preceding the diagnosis of preeclampsia : an observational study [PDF]

, 2016
Introduction. Some pregnant women develop significant proteinuria in the absence of hypertension. However, clinical significance of isolated gestational proteinuria (IGP) is not well understood.
Baba, Yosuke, Fujimori, Keiya, Hamada, Hiromi, Hirai, Chihiro, Ikeda, Tomoaki, Inde, Yusuke, Itakura, Atsuo, Kataoka, Soromon, Kawabata, Kosuke, Kudo, Yoshiki, Kusaka, Hideto, Maeda, Makoto, Minakami, Hisanori, Minakawa, Shiori, Murabayashi, Nao, Nagura, Michikazu, Nakai, Akihito, Obata-Yasuoka, Mana, Ohkuchi, Akihide, Ohno, Yasumasa, Sagawa, Norimasa, Umazume, Takeshi, Yamada, Takahiro, Yasuda, Shun   +23 more
core   +1 more source

Isoelectric point-amyloid formation of α-synuclein extends the generality of the solubility and supersaturation-limited mechanism

Current Research in Structural Biology, 2020
Proteins in either a native or denatured conformation often aggregate at an isoelectric point (pI), a phenomenon known as pI precipitation. However, only a few studies have addressed the role of pI precipitation in amyloid formation, the crystal-like ...
Koki Furukawa, Cesar Aguirre, Masatomo So, Kenji Sasahara, Yohei Miyanoiri, Kazumasa Sakurai, Keiichi Yamaguchi, Kensuke Ikenaka, Hideki Mochizuki, Jozsef Kardos, Yasushi Kawata, Yuji Goto   +11 more
doaj   +1 more source

Bacterial fermentation and isotope labelling optimized for amyloidogenic proteins

Microbial Biotechnology, 2021
Summary We developed a cost sensitive isotope labelling procedure using a fed‐batch fermentation method and tested its efficiency producing the 15N‐, 13C‐ and 15N/13C‐labelled variants of an amyloidogenic miniprotein (E5: EEEAVRLYIQWLKEGGPSSGRPPPS).
István Vida, Zsolt Fazekas, Gergő Gyulai, Dóra Nagy‐Fazekas, Gyula Pálfy, Pál Stráner, Éva Kiss, András Perczel   +7 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Exponential sensitivity of noise-driven switching in genetic networks [PDF]

, 2008
Cells are known to utilize biochemical noise to probabilistically switch between distinct gene expression states. We demonstrate that such noise-driven switching is dominated by tails of probability distributions and is therefore exponentially sensitive ...
Mehta, Pankaj, Mukhopadhyay, Ranjan, Wingreen, Ned S.   +2 more
core   +3 more sources

Antimicrobial Activity of Monoramnholipids Produced by Bacterial Strains Isolated from the Ross Sea (Antarctica)

Marine Drugs, 2016
Microorganisms living in extreme environments represent a huge reservoir of novel antimicrobial compounds and possibly of novel chemical families.
Pietro Tedesco, Isabel Maida, Fortunato Palma Esposito, Emiliana Tortorella, Karolina Subko, Chidinma Christiana Ezeofor, Ying Zhang, Jioji Tabudravu, Marcel Jaspars, Renato Fani, Donatella de Pascale   +10 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Replication of plasmids derived from Shiga toxinconverting bacteriophages in starved Escherichia coli [PDF]

, 2011
The pathogenicity of Shiga toxin-producing Escherichia coli (STEC) depends on the expression of stx genes that are located on lambdoid prophages. Effective toxin production occurs only after prophage induction, and one may presume that replication of the
Nadratowska-Wesołowska, Beata, Nejman, Bożena, Szalewska-Pałasz, Agnieszka, Węgrzyn, Alicja, Węgrzyn, Grzegorz   +4 more
core