Results 11 to 20 of about 18,638,167 (297)
P-selectin kDa) is encoded by the human SELP gene. This protein plays a role in leukocyte to platelets.
semanticscholar +2 more sources
P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin [PDF]
Neutrophils roll on P-selectin expressed by activated platelets or endothelial cells under the shear stresses in the microcirculation. P- selectin glycoprotein ligand-1 (PSGL-1) is a high affinity ligand for P- selectin on myeloid cells.
K. Moore +8 more
semanticscholar +3 more sources
A cell-extrinsic ligand acquired by activated T cells in lymph node can bridge L-selectin and P-selectin. [PDF]
P-selectin expressed on activated endothelia and platelets supports recruitment of leukocytes expressing P-selectin ligand to sites of inflammation.
Douglas A Carlow +2 more
doaj +1 more source
Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1. [PDF]
Stem bromelain, a cysteine protease isolated from pineapples, is a natural anti-inflammatory treatment, yet its mechanism of action remains unclear. Curious as to whether bromelain might affect selectin-mediated leukocyte rolling, we studied the ability ...
Jessica M Banks +2 more
doaj +1 more source
P-selectin blockade in COVID-19-related ARDS
TO THE EDITOR: Many patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) develop a syndrome that fulfills the Berlin definition for the acute respiratory distress syndrome (ARDS) characterized by very high mortality (14 ...
T. Neri, D. Nieri, A. Celi
semanticscholar +1 more source
Sulfation modulates the targeting properties of hyaluronic acid to P-selectin and CD44.
Many targeting strategies can be employed to direct nanoparticles to tumors for imaging and therapy. However, tumors display a dynamic, heterogeneous microenvironment that undergoes spatiotemporal changes, including the expression of targetable cell ...
D. Bhattacharya +5 more
semanticscholar +1 more source
Soluble P-selectin levels, P-selectin polymorphisms and cardiovascular disease [PDF]
P-selectin is a member of the selectin family of cell adhesion molecules which are important in the transient attachment of leukocytes to endothelial cells and platelets. A number of polymorphisms in the gene encoding P-selectin have been identified.
A M, Carter +3 more
openaire +2 more sources
Background P-selectin is a molecule participating in the inflammatory response through mediating cellular adhesion and essential for wound repair. However, studies regarding P-selectin in Bivalvia are rare. This study identified 90 P-selectin genes among
Yuanfeng Xu +4 more
doaj +1 more source
P-Selectin and Platelet Clearance [PDF]
P-selectin is an adhesion receptor for leukocytes expressed by activated platelets and endothelial cells. To assess a possible role of P-selectin in platelet clearance, we adapted an in vivo biotinylation technique in mice. Wild-type and P-selectin–deficient mice were infused with N-hydroxysuccinimido biotin.
G, Berger, D W, Hartwell, D D, Wagner
openaire +4 more sources

