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P-Selectin [PDF]

open access: yesDefinitions, 2020
P-selectin kDa) is encoded by the human SELP gene. This protein plays a role in leukocyte to platelets.

semanticscholar   +2 more sources

P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin [PDF]

open access: yesThe Journal of cell biology, 1995
Neutrophils roll on P-selectin expressed by activated platelets or endothelial cells under the shear stresses in the microcirculation. P- selectin glycoprotein ligand-1 (PSGL-1) is a high affinity ligand for P- selectin on myeloid cells.
K. Moore   +8 more
semanticscholar   +3 more sources

A cell-extrinsic ligand acquired by activated T cells in lymph node can bridge L-selectin and P-selectin. [PDF]

open access: yesPLoS ONE, 2018
P-selectin expressed on activated endothelia and platelets supports recruitment of leukocytes expressing P-selectin ligand to sites of inflammation.
Douglas A Carlow   +2 more
doaj   +1 more source

Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1. [PDF]

open access: yesPLoS ONE, 2013
Stem bromelain, a cysteine protease isolated from pineapples, is a natural anti-inflammatory treatment, yet its mechanism of action remains unclear. Curious as to whether bromelain might affect selectin-mediated leukocyte rolling, we studied the ability ...
Jessica M Banks   +2 more
doaj   +1 more source

P-selectin blockade in COVID-19-related ARDS

open access: yesAmerican Journal of Physiology - Lung cellular and Molecular Physiology, 2020
TO THE EDITOR: Many patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) develop a syndrome that fulfills the Berlin definition for the acute respiratory distress syndrome (ARDS) characterized by very high mortality (14 ...
T. Neri, D. Nieri, A. Celi
semanticscholar   +1 more source

Sulfation modulates the targeting properties of hyaluronic acid to P-selectin and CD44.

open access: yesACS Biomaterials Science & Engineering, 2020
Many targeting strategies can be employed to direct nanoparticles to tumors for imaging and therapy. However, tumors display a dynamic, heterogeneous microenvironment that undergoes spatiotemporal changes, including the expression of targetable cell ...
D. Bhattacharya   +5 more
semanticscholar   +1 more source

Soluble P-selectin levels, P-selectin polymorphisms and cardiovascular disease [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2003
P-selectin is a member of the selectin family of cell adhesion molecules which are important in the transient attachment of leukocytes to endothelial cells and platelets. A number of polymorphisms in the gene encoding P-selectin have been identified.
A M, Carter   +3 more
openaire   +2 more sources

Massive expansion of P-selectin genes in two Venerida species, Sinonovacula constricta and Mercenaria mercenaria: evidence from comparative genomics of Bivalvia

open access: yesBMC Genomics, 2022
Background P-selectin is a molecule participating in the inflammatory response through mediating cellular adhesion and essential for wound repair. However, studies regarding P-selectin in Bivalvia are rare. This study identified 90 P-selectin genes among
Yuanfeng Xu   +4 more
doaj   +1 more source

P-Selectin and Platelet Clearance [PDF]

open access: yesBlood, 1998
P-selectin is an adhesion receptor for leukocytes expressed by activated platelets and endothelial cells. To assess a possible role of P-selectin in platelet clearance, we adapted an in vivo biotinylation technique in mice. Wild-type and P-selectin–deficient mice were infused with N-hydroxysuccinimido biotin.
G, Berger, D W, Hartwell, D D, Wagner
openaire   +4 more sources

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