Results 21 to 30 of about 24,158,011 (265)

Eosinophil adhesion to nasal polyp endothelium is P-selectin-dependent.

open access: yes, 1994
Tissue eosinophilia is a characteristic feature of a number of inflammatory diseases including asthma and nasal polyposis. Eosinophil migration into tissues is controlled in part by interactions between eosinophil adhesion receptors and counter ...
Fiona A. Symon (7618805)   +7 more
core   +7 more sources

P-selectin expression tracks cerebral atrophy in Mexican-Americans

open access: yesFrontiers in Genetics, 2012
Background and Purpose. We hypothesized that the P-selectin (SELP) gene, localized to a region on chromosome 1q24, pleiotropically contributes to increased blood pressure (BP) and cerebral atrophy.
Peter eKochunov   +18 more
doaj   +2 more sources

Targeted Delivery to Dying Cells Through P-Selectin–PSGL-1 Axis: A Promising Strategy for Enhanced Drug Efficacy in Liver Injury Models [PDF]

open access: yesCells
To minimize off-target adverse effects and improve drug efficacy, various tissue-specific drug delivery systems have been developed. However, even in diseased organs, both normal and stressed, dying cells coexist, and a targeted delivery system ...
Te-Sheng Lien   +2 more
doaj   +2 more sources

Serum Levels of E-selectin and P-selectin In Alopecia Areata: A Case Control Study [PDF]

open access: yesZagazig University Medical Journal, 2022
Background: Alopecia areata (AA) is an inflammatory, nonscarring form of hair loss. Important variations in the clinical presentation of alopecia areata have been detected, extending from small, well-circumscribed blotches of hair loss to a complete ...
Hanan Sameer   +3 more
doaj   +1 more source

The Role of Platelet Cell Surface P-Selectin for the Direct Platelet-Tumor Cell Contact During Metastasis Formation in Human Tumors

open access: yesFrontiers in Oncology, 2021
Mammalian platelets, devoid of nuclei, are the smallest cells in the blood stream. They are essential for hemostasis, but also transmit cell signals that are necessary for regenerative and generative processes such as inflammation, immunity and tissue ...
Hans-Åke Fabricius   +2 more
doaj   +1 more source

Pulmonary exposure to carbon nanotubes promotes murine arterial thrombogenesis via platelet P-selectin

open access: yes, 2007
Carbon nanotubes, having a diameter as small as a few nanometers, yet with robust mechanical properties, can be functionalized with chemical and biological agents and be used for the delivery of target DNA molecules or peptides into specific tissues ...
P. Vandervoort (7579829)   +5 more
core   +6 more sources

Lung-Derived Selectins Enhance Metastatic Behavior of Triple Negative Breast Cancer Cells

open access: yesBiomedicines, 2021
The lung is one of the deadliest sites of breast cancer metastasis, particularly for triple negative breast cancer (TNBC). We have previously shown that the lung produces several soluble factors that may enhance the metastatic behavior of TNBC, including
Sami U. Khan   +4 more
doaj   +1 more source

Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1. [PDF]

open access: yesPLoS ONE, 2013
Stem bromelain, a cysteine protease isolated from pineapples, is a natural anti-inflammatory treatment, yet its mechanism of action remains unclear. Curious as to whether bromelain might affect selectin-mediated leukocyte rolling, we studied the ability ...
Jessica M Banks   +2 more
doaj   +1 more source

Soluble P-selectin levels, P-selectin polymorphisms and cardiovascular disease [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2003
P-selectin is a member of the selectin family of cell adhesion molecules which are important in the transient attachment of leukocytes to endothelial cells and platelets. A number of polymorphisms in the gene encoding P-selectin have been identified.
A M, Carter   +3 more
openaire   +2 more sources

P‐selectin in haemostasis [PDF]

open access: yesBritish Journal of Haematology, 2004
SummaryDuring the past decade, interrelationships between inflammation and thrombosis have been the subject of extensive works, and it is now commonly recognized that inflammation (notably leucocyte recruitment) directly affects thrombosis, and that thrombosis also constitutes a pro‐inflammatory event.
openaire   +2 more sources

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