Results 11 to 20 of about 80,651 (264)

Soluble P-selectin levels, P-selectin polymorphisms and cardiovascular disease [PDF]

Journal of Thrombosis and Haemostasis, 2003
P-selectin is a member of the selectin family of cell adhesion molecules which are important in the transient attachment of leukocytes to endothelial cells and platelets. A number of polymorphisms in the gene encoding P-selectin have been identified.
A M, Carter, K, Anagnostopoulou, M W, Mansfield, P J, Grant   +3 more
openaire   +2 more sources

Massive expansion of P-selectin genes in two Venerida species, Sinonovacula constricta and Mercenaria mercenaria: evidence from comparative genomics of Bivalvia

BMC Genomics, 2022
Background P-selectin is a molecule participating in the inflammatory response through mediating cellular adhesion and essential for wound repair. However, studies regarding P-selectin in Bivalvia are rare. This study identified 90 P-selectin genes among
Yuanfeng Xu, Xumeng Dong, Shuonan Ma, Cheng Luo, Jilin Xu   +4 more
doaj   +1 more source

P-Selectin and Platelet Clearance [PDF]

Blood, 1998
P-selectin is an adhesion receptor for leukocytes expressed by activated platelets and endothelial cells. To assess a possible role of P-selectin in platelet clearance, we adapted an in vivo biotinylation technique in mice. Wild-type and P-selectin–deficient mice were infused with N-hydroxysuccinimido biotin.
G, Berger, D W, Hartwell, D D, Wagner
openaire   +4 more sources

Role of P-selectin in platelet sequestration in pulmonary capillaries during endotoxemia [PDF]

, 2006
Background: There is growing evidence that platelets accumulate in the lung and contribute to the pathogenesis of acute lung injury during endotoxemia.
Alwin Eduard Goetz, Barry BE, Bevilacqua MP, Body SC, Brunk DK, Deuel TF, Dore M, Feuerhake F, Forde RC, Frenette PS, Greenberg AW, Handa K, Hattori R, Heffner JE, Kai Heckel, Kiefmann R, Kubes P, Kubo H, Kuebler WM, Kuhnle GE, Kuhnle GE, Kuklin V, Leo R, Ley K, Li N, Martina Dörger, Massberg S, Matsui NM, Okada Y, Parish CR, Piccardoni P, Rainer Kiefmann, Rinko LJ, Rodgers SD, Ruf A, Sonja Schenkat, Wang L, Williams MJ   +37 more
core   +1 more source

Platelets and galectins [PDF]

, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

Platelet-Induced Clumping of Plasmodium falciparum–Infected Erythrocytes from Malawian Patients with Cerebral Malaria—Possible Modulation In Vivo by Thrombocytopenia [PDF]

, 2008
Platelets may play a role in the pathogenesis of human cerebral malaria (CM), and they have been shown to induce clumping of Plasmodium falciparum–parasitized red blood cells (PRBCs) in vitro.
Barnwell JW, Beare NA, Calman Alexander MacLennan, Georges Emile Grau, Gerardin P, Israels SJ, Lewallen S, MacPherson GG, Malcolm Edward Molyneux, Mavuto Mukaka, Maxwell Kanjala, Ockenhouse CF, Samuel Crocodile Wassmer, Silamut K, Terrie Taylor, Thomas S, Udomsangpetch R, Wassmer SC, Yipp BG   +18 more
core   +1 more source

SELP Asp603Asn and severe thrombosis in COVID-19 males

Journal of Hematology & Oncology, 2021
Thromboembolism is a frequent cause of severity and mortality in COVID-19. However, the etiology of this phenomenon is not well understood. A cohort of 1186 subjects, from the GEN-COVID consortium, infected by SARS-CoV-2 with different severity was ...
Chiara Fallerini, Sergio Daga, Elisa Benetti, Nicola Picchiotti, Kristina Zguro, Francesca Catapano, Virginia Baroni, Simone Lanini, Alessandro Bucalossi, Giuseppe Marotta, Francesca Colombo, Margherita Baldassarri, Francesca Fava, Giada Beligni, Laura Di Sarno, Diana Alaverdian, Maria Palmieri, Susanna Croci, Andrea M. Isidori, Simone Furini, Elisa Frullanti, GEN-COVID Multicenter Study, Alessandra Renieri, Francesca Mari   +23 more
doaj   +1 more source

Endothelial dysfunction markers as a therapeutic target for Sildenafil treatment and effects on metabolic control in type 2 diabetes [PDF]

, 2015
Endothelial dysfunction (ED) plays a role in diabetic cardiovascular complications. Hyperglycemia increases cytockines involved in vascular inflammation.
Bertolini, Camilla, Fallarino, Mara, Filardi, Tiziana, Gianfrilli, Daniele, Giannetta, Elisa, Lenti, Luisa, Lenzi, Andrea, Lococo, Manuela, Mandosi, Elisabetta, Morano, Susanna, Venneri, MARY ANNA   +10 more
core   +1 more source

Glycosylation inhibitors efficiently inhibit P-selectin-mediated cell adhesion to endothelial cells. [PDF]

PLoS ONE, 2014
Adhesion molecules play a critical role in the adhesive interactions of multiple cell types in sickle cell disease (SCD). We previously showed that anti-P-selectin aptamer efficiently inhibits cell adhesion to endothelial cells (ECs) and permits SCD mice
Pushpankur Ghoshal, Mythilypriya Rajendran, Nadine Odo, Tohru Ikuta   +3 more
doaj   +1 more source

Correlation Between P-Selectin Level and Platelet Aggregation in Cerebral Venous Sinus Thrombosis Patients

Majalah Kedokteran Bandung, 2023
One of the causes of cerebral venous sinus thrombosis (CVST) is platelet hyperactivity. Adhesion and secretion are the beginning of platelet activation, which is indicated by a change in the Platelet-selectin (P-selectin) level.
Rahmawati Nurmin, Leni Lismayanti, Tiene Rostini, Agnes Rengga Indrati, Lisda Amalia   +4 more
doaj   +1 more source