Results 21 to 30 of about 18,638,167 (297)

Role of P-selectin in platelet sequestration in pulmonary capillaries during endotoxemia [PDF]

, 2006
Background: There is growing evidence that platelets accumulate in the lung and contribute to the pathogenesis of acute lung injury during endotoxemia.
Alwin Eduard Goetz, Barry BE, Bevilacqua MP, Body SC, Brunk DK, Deuel TF, Dore M, Feuerhake F, Forde RC, Frenette PS, Greenberg AW, Handa K, Hattori R, Heffner JE, Kai Heckel, Kiefmann R, Kubes P, Kubo H, Kuebler WM, Kuhnle GE, Kuhnle GE, Kuklin V, Leo R, Ley K, Li N, Martina Dörger, Massberg S, Matsui NM, Okada Y, Parish CR, Piccardoni P, Rainer Kiefmann, Rinko LJ, Rodgers SD, Ruf A, Sonja Schenkat, Wang L, Williams MJ   +37 more
core   +1 more source

Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo. [PDF]

, 2009
Myrtucommulone a nonprenylated acylphloroglucinol contained in the leaves of myrtle (Myrtus communis), has been reported to suppress the biosynthesis of eicosanoids by inhibition of 5-lipoxygenase and cyclooxygenase-1 in vitro and to inhibit the release ...
BRAMANTI P., CAMINITI R., CUZZOCREA S., DI PAOLA R., GENOVESE T., KOEBERLE A., MAZZON E., PERGOLA C., ROSSI, ANTONIETTA, SAUTEBIN, LIDIA, WERZ O.   +10 more
core   +1 more source

P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Complement system activation occurs in sickle cell disease and other hemolytic disorders, but the pathological relevance and the acquisition of a complement-activating phenotype by host cells during hemolysis remain unclear.
N. Merle, R. Paule, J. Léon, Marie V. Daugan, Tania Robe-Rybkine, Victoria Poillerat, Carine Torset, V. Frémeaux-Bacchi, J. Dimitrov, L. Roumenina   +9 more
semanticscholar   +1 more source

Platelets and galectins [PDF]

, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

SELP Asp603Asn and severe thrombosis in COVID-19 males

Journal of Hematology & Oncology, 2021
Thromboembolism is a frequent cause of severity and mortality in COVID-19. However, the etiology of this phenomenon is not well understood. A cohort of 1186 subjects, from the GEN-COVID consortium, infected by SARS-CoV-2 with different severity was ...
Chiara Fallerini, Sergio Daga, Elisa Benetti, Nicola Picchiotti, Kristina Zguro, Francesca Catapano, Virginia Baroni, Simone Lanini, Alessandro Bucalossi, Giuseppe Marotta, Francesca Colombo, Margherita Baldassarri, Francesca Fava, Giada Beligni, Laura Di Sarno, Diana Alaverdian, Maria Palmieri, Susanna Croci, Andrea M. Isidori, Simone Furini, Elisa Frullanti, GEN-COVID Multicenter Study, Alessandra Renieri, Francesca Mari   +23 more
doaj   +1 more source

Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-α [PDF]

, 2000
Brief episodes of ischemia can render an organ resistant to subsequent severe ischemia. This ‘ischemic preconditioning’ is ascribed to various mechanisms, including oxidative stress. We investigated whether preconditioning exists on an endothelial level.
Akimitsu T., BERNHARD F. BECKER, CHRISTIAN KUPATT, DeFily D. V., Hearse D. J., Hoshida S., Jerome S. N., Schreck R., Schulz R., Siegfried M. R., STEFAN ZAHLER, Yao Z.   +11 more
core   +1 more source

Glycosylation inhibitors efficiently inhibit P-selectin-mediated cell adhesion to endothelial cells. [PDF]

PLoS ONE, 2014
Adhesion molecules play a critical role in the adhesive interactions of multiple cell types in sickle cell disease (SCD). We previously showed that anti-P-selectin aptamer efficiently inhibits cell adhesion to endothelial cells (ECs) and permits SCD mice
Pushpankur Ghoshal, Mythilypriya Rajendran, Nadine Odo, Tohru Ikuta   +3 more
doaj   +1 more source

Correlation Between P-Selectin Level and Platelet Aggregation in Cerebral Venous Sinus Thrombosis Patients

Majalah Kedokteran Bandung, 2023
One of the causes of cerebral venous sinus thrombosis (CVST) is platelet hyperactivity. Adhesion and secretion are the beginning of platelet activation, which is indicated by a change in the Platelet-selectin (P-selectin) level.
Rahmawati Nurmin, Leni Lismayanti, Tiene Rostini, Agnes Rengga Indrati, Lisda Amalia   +4 more
doaj   +1 more source

New in vitro effects of clopidogrel on platelets in hyperlipidemic and healthy subjects [PDF]

, 2010
Objective: We aimed to detect novel in vitro effects of clopidogrel on platelets by assessment of the following parameters: malondialdehyde, glutathione, nitrite, aggregation response, and expressions of P-selectin, fibrinogen, apolipoprotein A1 ...
Azize Şener, Derya Özsavcı, Fikriye Uras, Gülderen Yanıkkaya Demirel, Rabia Oba, Turay Kevser Yardımcı   +5 more
core   +2 more sources

Effects of astragalus polysaccharide on the adhesion-related immune response of endothelial cells stimulated with CSFV in vitro [PDF]

PeerJ, 2017
Background Astragalus polysaccharide (APS) has immunomodulatory activities on porcine peripheral blood mononuclear cells. The immunomodulatory effects of APS on porcine endothelial cells (ECs) expose to classical swine fever virus (CSFV) remain unknown ...
Zengyu Zhuge, Yanpeng Dong, Liuan Li, Tianming Jin   +3 more
doaj   +2 more sources