Results 91 to 100 of about 23,995,070 (219)

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

Biotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen, Anton Du Preez van Staden, Leon M. T. Dicks   +2 more
wiley   +1 more source

Cell surface display of functionally active lipases from Yarrowia lipolytica in Pichia pastoris

, 2007
The lipase genes of Yarrowia lipolytica, LIPY7 and LIPY8, fused with FLO-flocculation domain sequence from Saccharomyces cerevisiae at their N-termini, were expressed in Pichia pastoris KM71.
Song, Hui-Ting, Wu, Zhen-Bin, Jiang, Zheng-Bing, Ma, Li-Xin, Jiang, ZB, Hubei Univ, Coll Life Sci, Wuhan 430062, Peoples R China, Gupta, Nishith   +5 more
core   +1 more source

Deciphering cell wall sensors enabling the construction of robust P. pastoris for single-cell protein production. [PDF]

Biotechnol Biofuels Bioprod, 2023
Gao L, Meng J, Dai W, Zhang Z, Dong H, Yuan Q, Zhang W, Liu S, Wu X.   +8 more
europepmc   +1 more source

Cloning, Expression, and Functional Characterization of Autoactivated Human Prethrombin-2 Synthetic Gene by Using Pichia pastoris SMD1168 As a Host

Microbiology Indonesia, 2016
Prethrombin-2 is a thrombin precursor that has important role in blood coagulation. It is the smallest precursor which is activated into thrombin by FXa prior to coagulation process.
TOTO SUBROTO, WULAN PERTIWI, MUHAMMAD FADHILLAH, KHOMAINI HASAN, OGI BUDIANTORO, SUTARYA ENUS, SOETIJOSO SOEMITRO   +6 more
doaj   +1 more source

High-level production of recombinant HBcAg virus-like particles in a mathematically modelled P. pastoris GS115 Mut⁺ bioreactor process under controlled residual methanol concentration. [PDF]

Bioprocess Biosyst Eng, 2022
Bolmanis E, Grigs O, Kazaks A, Galvanauskas V.   +3 more
europepmc   +1 more source

Rewiring Carbon Metabolism in Bacillus methanolicus via Heterologous Phosphoketolase Expression Enhances Biomass Yield From Methanol and Reduces CO2 Loss

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
Introducing a phosphoketolase pathway into Bacillus methanolicus enhances methanol‐to‐biomass yields by 18%–24% and reduces CO2 evolution by up to 12%. Coupled with a tunable expression system, this work demonstrates improved carbon conservation and expands metabolic engineering strategies for methylotrophs.
Yael J. Toporek, Jonathan R. Humphreys, Thomas J. Musselwhite, Marcus S. Bray, Katie P. Michel, Kimberly A. Rosenbach, Michael T. Guarnieri   +6 more
wiley   +1 more source

Codon usage bias regulates gene expression and protein conformation in yeast expression system P. pastoris. [PDF]

Microb Cell Fact, 2021
Xu Y, Liu K, Han Y, Xing Y, Zhang Y, Yang Q, Zhou M.   +6 more
europepmc   +1 more source

The Triglyceride‐Glucose (TyG) Index and Incident Diabetes and Cardiovascular Events in People Living With HIV‐1 Infection. A 14‐Year Observational Cohort Study

European Journal of Clinical Investigation, Volume 56, Issue 9, September 2026.
People living with HIV (PWH) face an increased risk of Type 2 diabetes mellitus (T2DM) and cardiovascular events (CVEs), highlighting the need for simple risk stratification tools. In this retrospective study of 477 PWH followed for 14.2 years, a higher triglyceride‐glucose (TyG) index independently predicted incident T2DM and CVEs.
Daniele Pastori, Gianluca Gazzaniga, Tommaso Brogi, Marco Rivano Capparuccia, Caterina Fimiani, Claudio Mastroianni, Ivano Mezzaroma   +6 more
wiley   +1 more source

A cytoplasm to vacuole targeting pathway in P-pastoris [PDF]

, 2007
The cytoplasm-to-vacuole targeting (Cvt) pathway of Saccharomyces cerevisiae delivers aminopeptidase I (Ape 1) from the cytosol to the vacuole, bypassing the normal secretary route. The Cvt pathway, although well-studied, was known only in S. cerevisiae.
Farré, Jean-Claude, Subramani, Suresh, Vidal, Jason   +2 more
core  

Glycosylation of thrombospondin type 1 repeats [PDF]

, 2008
In the course of mutagenesis of the forth thrombospondin type 1 repeat (TSR4) of the axonal guidance protein F-spondin, one mutant designated ΔDS2,3-TSR4 missing two out of three cystein bridges was found to lack the disaccharide Glcβ1,3-Fuc-O.
Krantz, Carsten
core   +1 more source