Results 31 to 40 of about 23,995,070 (219)
Design of an optimised fed-batch process for insulin precursor production in Pichia pastoris [PDF]
, 2011 Includes bibliographical references (leaves 98-103).The increasing prevalence of diabetes worldwide has greatly increased the demand for insulin, a key type of treatment for many diabetics.
Bhardwaj, Vinayak
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Screening for functional IRESes using α-complementation system of β-galactosidase in Pichia pastoris
Biotechnology for Biofuels, 2019 Background Pichia pastoris is becoming a promising chassis cell for metabolic engineering and synthetic biology after its whole genome and transcriptome sequenced. However, the current systems for multigene co-expression in P. pastoris are not efficient.
Yide Huang +5 more
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Microbial Cell Factories, 2005 The methylotrophic yeast Pichia pastoris is a popular heterologous expression host for the recombinant production of a variety of prokaryotic and eukaryotic proteins. The rapid emergence of P.
Gurkan Cemal, Ellar David J
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AMB Express, 2021 The negative effects of lignocellulose-derived inhibitors such as acetic acid and furaldehydes on microbial metabolism constitute a significant drawback to the usage of biomass feedstocks for the production of fuels and chemicals.
Barbara G. Paes +4 more
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Extracellular Production of the Taiwan-Native Norovirus P Domain Overexpressed in Pichia pastoris
Fermentation, 2023 Many efforts in norovirus vaccine development have focused on subunit or recombinant protein vaccines, such as subviral P particles formed by the protruding (P) domain of VP1. P particles are immunogenic and have a region with a human histo-blood group antigen binding site, an interaction critical for infecting the host. In the past, only intracellular
Chien, Man-Ling +2 more
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Microbial Cell Factories, 2004 Background Pichia pastoris is a well established yeast host for heterologous protein expression, however, the physiological and genetic information about this yeast remains scanty.
Porro Danilo +6 more
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Screening and evaluation of the strong endogenous promoters in Pichia pastoris
Microbial Cell Factories, 2021 Background Due to its ability to perform fast and high-density fermentation, Pichia pastoris is not only used as an excellent host for heterologous protein expression but also exhibits good potential for efficient biosynthesis of small-molecule compounds.
Weiwang Dou +4 more
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Methanol-based biosynthesis of p-coumaric acid by engineered Pichia pastoris. [PDF]
Bioresour BioprocessAbstract p -Coumaric acid (p-CA) is a key aromatic precursor for the biosynthesis of flavonoids, stilbenoids, and other high-value phenylpropanoids. While microbial production of p-CA typically relies on sugar-based substrates, methanol offers a sustainable and cost-effective alternative ...
Chen M +7 more
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Bioresources and Bioprocessing, 2017 Background Pichia pastoris is one of the most important cell factories for production of industrial enzymes and heterogenous proteins. The genome-scale metabolic model of high quality is crucial for comprehensive understanding of the P.
Rui Ye +7 more
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Microbial Cell Factories, 2012 Background Yeast mating provides an efficient means for strain and library construction. However, biotechnological applications of mating in the methylotrophic yeast Pichia pastoris have been hampered because of concerns about strain stability of P ...
Chen Ming-Tang +5 more
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