Results 121 to 130 of about 212,746 (279)

Transoral Robotic Surgery (TORS) for Head and Neck Cancer in the Elderly Population: Functional Outcomes, Survival, and Complications

Head &Neck, EarlyView.
ABSTRACT Objective To compare functional and oncologic outcomes in elderly (≥ 70 years) and nonelderly (< 70 years) patients after transoral robotic surgery (TORS). Methods A retrospective chart review was conducted on 114 patients who underwent TORS for head and neck squamous cell carcinoma between 2012 and 2022.
Erim Pamuk, Avinash Beharry, Karma Lambercy, Margaux Dalla‐Vale, Nina Wahler, Şefik Hoşal, Christian Simon   +6 more
wiley   +1 more source

Risk of Occult Contralateral Neck Metastasis in Early‐Stage HPV‐Related Lateralized Cancer of the Base of the Tongue

Head &Neck, EarlyView.
ABSTRACT Objectives (1) To determine the incidence of occult contralateral cervical lymph node metastasis in patients with early‐stage HPV‐associated base‐of‐tongue (BOT) oropharyngeal squamous cell carcinoma (OPSCC) treated with primary surgery; and (2) to compare survival and recurrence in patients who did and did not undergo contralateral neck ...
Tyler R. Halle, Austin C. Cao, Anusha G. Naik, Gregory S. Weinstein, Jake J. Lee, Theodore A. Gobillot, Erin R. Kaye, Robert M. Brody, Devraj Basu, Bert W. O'Malley Jr, D. Gregory Farwell, Steven B. Cannady, Alexander Lin, John Lukens, Michelle Gentile, Jason G. Newman, Ara A. Chalian, Christopher H. Rasskeh, Karthik Rajasekaran   +18 more
wiley   +1 more source

Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios Predict Improved Survival and Response to Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Larynx

Head &Neck, EarlyView.
ABSTRACT Background University of Michigan Cancer Center (UMCC) protocol 9520 treated stage III/IV locally advanced squamous cell carcinoma of the larynx (LASCCL) with cisplatin and 5‐fluorouracil to select for definitive therapy based on response.
Zachary Risch, Emily Bellile, Moneb S. Bughrara, Paul L. Swiecicki, Keith Casper, Kelly Malloy, Norman Hogikyan, Matthew Spector, Andrew Shuman, Chaz Stucken, Steven Chinn, Douglas C. Chepeha, Shruti Jolly, Michelle Mierzwa, Carol Bradford, Avraham Eisbruch, Thomas Carey, Mark Prince, Gregory T. Wolf, Francis P. Worden   +19 more
wiley   +1 more source

Efficacy of Multimodal Work‐Up of Head and Neck Squamous Cell Carcinoma Lymph Node Metastasis of Unknown Primary

Head &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) often presents with cervical lymph node metastasis, with 1%–4% of cases presenting as cancer of unknown primary (CUP). CUP poses diagnostic and therapeutic challenges and is linked to poorer survival outcomes.
Robin W. Jansen, Roland M. Martens, Obaida Abdulrahman, Laura Peferoen, C. René Leemans, Gerben J. C. Zwezerijnen, Jan‐Jaap Hendrickx, Pim de Graaf   +7 more
wiley   +1 more source

Prognostic analysis of inconsistent combinations of HPV and p16 in a Chinese/Asian oropharyngeal squamous cell carcinoma population

Infectious Agents and Cancer
Background The aim of this study was to investigate the effect of inconsistent expression of p16 and HPV on the prognosis of patients with Oropharyngeal squamous cell carcinoma (OPSCC) in Chinese/Asian populations. Methods The study included 130 patients.
Jieying Li, Kai Zhou, Xiaohong Zhan, Haijun Lu, Dapeng Hao, Kai Song, Shuangyi Wang, Yuanyong Feng, Haoyue Xu, Zongxuan He, Xiaochen Yang, Wei Shang, Lin Wang   +12 more
doaj   +1 more source

p16 expression in oropharyngeal cancer: its impact on staging and prognosis compared with the conventional clinical staging parameters [PDF]

, 2017
Background: Currently, staging of head neck squamous cell carcinoma (HNSCC) is on the basis of primary tumor extension (cT), lymph node involvement (cN) and distant metastasis (cM).
Fischer, C. A., Green, E., Kampmann, M., Lugli, A., Terracciano, L. M., Tornillo, L., Wolfensberger, M., Zlobec, I.   +7 more
core  

Intraoperative Molecular Imaging Can Detect Large Nerve Perineural Invasion: A Case Report

Head &Neck, EarlyView.
ABSTRACT Background Perineural invasion (PNI) in head and neck squamous cell carcinoma (SCC) results in worse overall survival. Diagnosis requires resection and microscopic evaluation. Methods A 63‐year‐old male with persistent cT4aN0 p16‐positive SCC of the left base of tongue following chemoradiotherapy underwent salvage total glossectomy ...
Carleigh R. Burns, Aviva S. Mattingly, Kim Ely, Andreja Radevic, Nicole Meeks, Sydea Maria Ahmad Zaidi, Brandee Brown, Georgii Vasiukov, Michael Topf, Eben Rosenthal   +9 more
wiley   +1 more source

Oncological Outcomes of Salvage Oropharyngectomy in Irradiated Neck for Recurrent or Metachronous Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate oncological outcomes and their predictors following salvage oropharyngectomy. Methods This single‐center retrospective study included patients who underwent a salvage oropharyngectomy in an irradiated neck for recurrent or metachronous oropharyngeal squamous cell carcinoma (OPSCC) between 2014 and 2023.
Jade Saykaly, Sébastien Vergez, Agnès Dupret‐Bories, Anouchka Modesto, Benjamin Vairel, Jérôme Sarini, Aurore Siegfried, Ana Cavillon, Emilien Chabrillac   +8 more
wiley   +1 more source

How Would You Treat? A Case‐Vignette Study of Provider Treatment Preferences in Human Papillomavirus‐Mediated Oropharyngeal Cancer

Head &Neck, EarlyView.
ABSTRACT Background Current guidelines recommend surgical resection, definitive radiotherapy (RT), or concurrent chemoradiotherapy (CRT) for human papillomavirus (HPV)‐associated oropharyngeal squamous cell carcinoma (OPSCC). This study aimed to provide insight into practice patterns of providers who treat HPV‐associated OPSCC.
Sindhura Sridhar, Michael R. Papazian, Michael C. Topf   +2 more
wiley   +1 more source

Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice. [PDF]

, 2008
ObjectiveThe aim of this study was to elucidate whether age plays a role in the expansion or regeneration of beta-cell mass.Research design and methodsWe analyzed the capacity of beta-cell expansion in 1.5- and 8-month-old mice in response to a high-fat ...
Bhushan, Anil, Dhawan, Sangeeta, Gurlo, Tatyana, Tschen, Shuen-Ing   +3 more
core   +1 more source