Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer. [PDF]
Chaudhary R +22 more
europepmc +1 more source
“It's just us”: Families' experiences with temporary tube feeding
Abstract Background Children with temporary feeding tubes are discharged home with increasing frequency, yet little is known about how families adapt and manage in their home environment. Whereas the physical side effects of temporary feeding tubes are well documented, the psychosocial impact on families remains underresearched. Understanding families'
Claire Reilly +4 more
wiley +1 more source
The Diagnostic and Prognostic Role of Combined p16 and MTAP Immunohistochemistry in Melanocytic Tumors of Uncertain Malignant Potential: A Comprehensive Review and Clinical Practice Analysis. [PDF]
Pepe L +8 more
europepmc +1 more source
ABSTRACT Objective Aging alters mesenchymal stromal cell (MSC) function, leading to dysregulated adipogenesis across tissues through biased lineage commitment. Fat redistribution from adipose depots to skeletal muscle and bone marrow is common in aging, but the underlying mechanisms remain unclear.
Xu Zhang +13 more
wiley +1 more source
Treatment Interruption and Outcomes in Head and Neck Cancer: A Secondary Analysis of 3 Randomized Clinical Trials. [PDF]
Gharzai LA +22 more
europepmc +1 more source
Abstract Objective The objective was to identify clinical variables associated with microscopic positive margins (PMs) during transoral robotic surgery (TORS) for oropharyngeal cancer (OPC) resection, and to explore the association of the receipt of adjuvant treatment with overall survival (OS) in this population.
Aaron Tucker, Craig A. Bollig
wiley +1 more source
Hypertension and age-related focal global glomerulosclerosis are associated with biomarkers for cellular senescence. [PDF]
Hughson MD +4 more
europepmc +1 more source
Evaluation der Häufigkeit von Halslymphknotenmetastasen bei P16+ vs. P16 - Oropharynxkarzinomen
Jadeed, R +3 more
openaire +2 more sources
Exploration of Therapeutic Targets Using CDK4 Inhibitors for Head and Neck Mucosal Melanoma
Abstract Objective Mucosal melanoma (MM) is an extremely aggressive malignant tumor in the head and neck region associated with a poor prognosis. In the present study, we conducted cell proliferation assay and western blotting using cell lines derived from MM and the immunohistochemical analysis of pathological MM tissues to identify novel therapeutic ...
Takayoshi Hattori +14 more
wiley +1 more source
Cellular Senescence in the Ascending Aorta and Complexity of Coronary Atherosclerosis. [PDF]
Abanus H +5 more
europepmc +1 more source

