Abstract Objective Dysphagia is a major toxicity of chemoradiation (CRT) for oropharyngeal squamous cell carcinoma (OPSCC). Elective upper‐neck irradiation (UNI), omitting the low neck, may reduce esophageal inlet muscle (EIM) dose and improve swallowing outcomes compared to elective whole‐neck irradiation (WNI).
Rex H. Lee +7 more
wiley +1 more source
Menopausal timing and senescent-immune coupling in age-related lobular involution of the human breast: a longitudinal cohort study. [PDF]
Lue JC +13 more
europepmc +1 more source
Synthesis of Poly(Itaconate)s With High Monomer Conversion Applying Emulsion Polymerization
Itaconic acid and its derivatives are a promising and bio‐based substitute for oil‐based polymers such as acrylates. In this study, the optimization of polymerization of itaconic acid esters is described by applying emulsion polymerization leading to high reaction conversions and low residual monomer contents. ABSTRACT Itaconic acid and its derivatives
S. Charlotte Fischer von Mollard +5 more
wiley +1 more source
Microsatellite instability in penile cancer: comparative analysis of primary tumors and metastases. [PDF]
Araujo HS +6 more
europepmc +1 more source
Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley +1 more source
[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer. [PDF]
Hong L +7 more
europepmc +1 more source
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley +1 more source
Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi +5 more
wiley +1 more source
The impact of physiological oxidants on triggering amyloid formation of the cell cycle regulator protein p16<sup>INK4A</sup>. [PDF]
Smith BR +6 more
europepmc +1 more source

