Results 1 to 10 of about 217,248 (344)

Molecular Characterisation of NKR-P1 receptor in peripheral blood of Pig [PDF]

Veterinary World, 2008
Characterization of natural killer receptor-p1 (NKR-P1) in the leukocytes from peripheral blood of pig revealed three different clones of NKR-P1, 1,2 and 3. The RT-PCR product of human NKR-P1 gene was 573 base pair (bp).
Banshi Sharma, Marc Goaverts, Prof. Bruno Godderris   +2 more
doaj   +2 more sources

Systematic analyses of the sequence conservation and ligand interaction patterns of purinergic P1 and P2Y receptors provide a structural basis for receptor selectivity

Computational and Structural Biotechnology Journal, 2023
Purinergic receptors are membrane proteins that regulate numerous cellular functions by catalyzing reactions involving purine nucleotides or nucleosides.
Ri Han, Hongryul Yoon, Jiho Yoo, Yoonji Lee   +3 more
doaj   +2 more sources

Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival [PDF]

Frontiers in Cellular Neuroscience, 2019
Purinergic signaling regulates important physiological processes and the homeostatic response to stress in the cochlea via extracellular nucleosides (adenosine) and nucleotides (ATP, UTP).
Shelly C. Y. Lin, Peter R. Thorne, Gary D. Housley, Srdjan M. Vlajkovic   +3 more
doaj   +2 more sources

Nuclear Respiratory Factor 1 Negatively Regulates the P1 Promoter of the Peroxisome Proliferator-Activated Receptor-γ Gene and Inhibits Chicken Adipogenesis

Frontiers in Physiology, 2018
Peroxisome proliferator-activated receptor-γ (PPARγ) is a master regulator of adipogenesis, and alterations in its function are associated with various pathological processes related to metabolic syndrome.
Tingting Cui, Tingting Cui, Tingting Cui, Tingting Cui, Tianyu Xing, Tianyu Xing, Tianyu Xing, Jiaxin Huang, Jiaxin Huang, Jiaxin Huang, Fang Mu, Fang Mu, Fang Mu, Yanfei Jin, Yanfei Jin, Yanfei Jin, Xin You, Xin You, Xin You, Yankai Chu, Yankai Chu, Yankai Chu, Hui Li, Hui Li, Hui Li, Ning Wang, Ning Wang, Ning Wang   +27 more
doaj   +2 more sources

Neuropeptide F regulates courtship in Drosophila through a male-specific neuronal circuit [PDF]

eLife, 2019
Male courtship is provoked by perception of a potential mate. In addition, the likelihood and intensity of courtship are influenced by recent mating experience, which affects sexual drive.
Weiwei Liu, Anindya Ganguly, Jia Huang, Yijin Wang, Jinfei D Ni, Adishthi S Gurav, Morris A Aguilar, Craig Montell   +7 more
doaj   +3 more sources

Adenosine receptors as emerging therapeutic targets for diabetic kidney disease [PDF]

Kidney Research and Clinical Practice, 2022
Diabetic kidney disease (DKD) is now a pandemic worldwide, and novel therapeutic options are urgently required. Adenosine, an adenosine triphosphate metabolite, plays a role in kidney homeostasis through interacting with four types of adenosine receptors
Eun Seon Pak, Jin Joo Cha, Dae Ryong Cha, Keizo Kanasaki, Hunjoo Ha   +4 more
doaj   +1 more source

Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): Intracerebral hemorrhage (ICH) occurs mostly in the striatum. In ICH, blood prolactin level increases 3-fold. The effects of intracerebroventricular injection (ICV) of prolactin on motor disorders will be investigated. Materials and Methods:
Shiba Yousefvand, Mousa-al-Reza Hadjzadeh, Zakieh Keshavarzi, Hamid Dolatshad, Farzaneh Vafaei, Maryam Mahmoudabady, Zahra Gholamzadeh Virany   +6 more
doaj   +1 more source

Role of purinergic signalling in obesity-associated end-organ damage: focus on the effects of natural plant extracts

Frontiers in Endocrinology, 2023
Obesity has become one of the major public health problems in both the developing and developed countries. Recent studies have suggested that the purinergic signalling is involved in obesity-associated end-organ damage through purine P1 and P2 receptors.
Hangxiu Che, Hangxiu Che, Yaqun Wang, Jinhui Lao, Yixin Deng, Chirui Xu, Hanxiao Yin, Zheng Tang, Yonghong Huang, Hong Xu   +9 more
doaj   +1 more source

Analysis of the HNF4A isoform-regulated transcriptome identifies CCL15 as a downstream target in gastric carcinogenesis

Cancer Biology & Medicine, 2021
Objective: Hepatocyte nuclear factor 4α (HNF4A) has been demonstrated to be an oncogene in gastric cancer (GC). However, the roles of different HNF4A isoforms derived from the 2 different promoters (P1 and P2) and the underlying mechanisms remain obscure.
Zhen Ni, Wenquan Lu, Qi Li, Chuan Han, Ting Yuan, Nina Sun, Yongquan Shi   +6 more
doaj   +1 more source

Targeting ErbB3 Receptor in Cancer with Inhibitory Antibodies from Llama

Biomedicines, 2021
The human ErbB3 receptor confers resistance to the pharmacological inhibition of EGFR and HER2 receptor tyrosine kinases in cancer, which makes it an important therapeutic target.
Igor E. Eliseev, Valeria M. Ukrainskaya, Anna N. Yudenko, Anna D. Mikushina, Stanislav V. Shmakov, Anastasiya I. Afremova, Viktoria M. Ekimova, Anna A. Vronskaia, Nickolay A. Knyazev, Olga V. Shamova   +9 more
doaj   +1 more source