Results 101 to 110 of about 126,105 (250)

Experimental Line Parameters of the b^(1)Σ^(+)_g ← X^(3)Σ^(-)_g Band of Oxygen Isotopologues at 760 nm Using Frequency-Stabilized Cavity Ring-Down Spectroscopy [PDF]

, 2009
Positions, intensities, self-broadened widths, and collisional narrowing coefficients of the oxygen isotopologues ^(16)O^(18)O, ^(16)O^(17)O, ^(17)O^(18)O, and ^(18)O^(18)O have been measured for the b^(1)Σg + ← X^(3)Σg − (0,0) band using frequency ...
Brown, Linda R., Havey, Daniel K., Hodges, Joseph T., Long, David A., Miller, Charles E., Okumura, Mitchio, Robichaud, David J., Yeung, Laurence Y.   +7 more
core  

Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation [PDF]

, 2007
MicroRNAs (miRNAs) are potent post-transcriptional regulators of protein coding genes. Patterns of misexpression of miRNAs in cancer suggest key functions of miRNAs in tumorigenesis.
Carlos le Sage, Remco Nagel, David A Egan, Mariette Schrier, Elly Mesman, Annunziato Mangiola, Corrado Anile, Giulio Maira, Neri Mercatelli, Silvia Anna Ciafrè, Maria Giulia Farace, Reuven Agami, Alessandrini A, Bagga S, Brummelkamp TR, Calin GA, Chilosi M, Chu I, Ciafre SA, Esquela-Kerscher A, Fero ML, Giraldez AJ, Grimmler M, He H, He L, Hengst L, Hershko DD, Kaldis P, Kardinal C, Kedde M, Kent OA, Kloosterman WP, Koff A, Krutzfeldt J, Le XF, Lee EJ, Loda M, Lu CD, Lu J, Mayr C, Migita T, Millard SS, Mineta H, Pallante P, Ponce-Castaneda MV, Porter PL, Voorhoeve PM, Wu L   +47 more
core   +4 more sources

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol, Ana Martínez‐Vacas, David García‐Bernal, Manuel Vidal‐Sanz, María Paz Villegas‐Pérez, Diego García‐Ayuso, Johnny Di Pierdomenico   +6 more
wiley   +1 more source

Translational Oncogenomics and Human Cancer Interactome Networks [PDF]

, 2011
An overview of translational, human oncogenomics, transcriptomics and cancer interactomic networks is presented together with basic concepts and potential, new applications to Oncology and Integrative Cancer Biology.
I. C. Baianu
core   +1 more source

Nexrutine Inhibits Cancer Cell Growth as a Consequence of Mitochondrial Damage and Mitophagy

Cellular Physiology and Biochemistry, 2015
Background/Aims: Nexrutine is an herbal extract of Phellodendron amurense and has been used as nutrient supplement in China as well as America. Potential protection effect of Nexrutine has been reported. Methods: To investigate the mechanism of Nexrutine,
Xiang Wu, Shao-ming Zhou, Yi-Ling Ding, Ying-ping Gong, Weiqi Zeng, Yi Cui   +5 more
doaj   +1 more source

Rethinking the role of HIF in hepatocellular carcinoma

The FEBS Journal, EarlyView.
Tumor hypoxia is a hallmark of cancer driving disease, in part through activation of hypoxia‐inducible factors (HIFs). While HIF‐1α is classically understood as a hypoxia‐responsive transcription factor, its role under normoxic conditions in cells is less clear.
Niall S. Kenneth, Michael Batie, Sonia Rocha   +2 more
wiley   +1 more source

Assessing inconsistencies in the FITradeoff method: a comparison of two preference modeling paradigms

International Transactions in Operational Research, EarlyView.
Abstract Many decision‐making processes are susceptible to errors and inconsistencies introduced by decision‐makers (DMs). The development of decision support systems (DSS) has brought about a way to guide DMs through complex decision scenarios. However, due to the complexity of the process, inconsistencies may still arise.
Evanielle Barbosa Ferreira, Lucia Reis Peixoto Roselli, Adiel Teixeira de Almeida   +2 more
wiley   +1 more source

Higgs-regularized three-loop four-gluon amplitude in N=4 SYM: exponentiation and Regge limits

, 2010
We compute the three-loop contribution to the N=4 supersymmetric Yang-Mills planar four-gluon amplitude using the recently-proposed Higgs IR regulator of Alday, Henn, Plefka, and Schuster.
Henn, Johannes M., Naculich, Stephen G., Schnitzer, Howard J., Spradlin, Marcus   +3 more
core   +1 more source

Curcumin inhibits 3T3-L1 preadipocyte proliferation by mechanisms involving post-transcriptional p27 regulation

Biochemistry and Biophysics Reports, 2016
Previous reports from our lab have shown that Skp2 is necessary for p27 degradation and cell cycle progression during adipocyte differentiation. Data presented here demonstrate that the anti-inflammatory, anti-obesity phytochemical curcumin blocked Skp2 ...
Bradley S. Ferguson, Heesun Nam, Ron F. Morrison   +2 more
doaj   +1 more source